Primary carcinoma involving the petrous temporal bone

Authors

  • Dr. Fei-Fei Liu MD, FRCPC,

    Corresponding author
    1. Department of Radiation Oncology, Princess Margaret Hospital/Ontario Cancer Institute, Toronto, Ontario, Canada
    • Department of Radiation Oncology, Princess Margaret Hospital/Ontario Cancer Institute, 500 Sherbourne Street, Toronto, Ontario M4X 1Kg, Canada
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  • Thomas J. Keane MB, MRCPI, FRCPC,

    1. Department of Radiation Oncology, Princess Margaret Hospital/Ontario Cancer Institute, Toronto, Ontario, Canada
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  • Jean Davidson MD, FRCSC

    1. Department of Otolaryngology, St. Michael's Hospital, Toronto, Ontario, Canada
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Abstract

Between 1975 and 1985, 29 patients with the diagnosis of carcinoma of the petrous temporal bone were seen at the Princess Margaret Hospital. Twenty-seven carcinomas were graded: 13 were well-differentiated; the remaining 14 were either moderately or poorly differentiated tumors. Fifteen patients were managed with a combination of surgery and radiotherapy, 13 were treated with radiotherapy only, and one patient was treated by surgery alone. Median follow-up time was 6.1 years, and the 5-year actuarial local control and cause-specific survival rates for the entire group were 40% and 50%, respectively. Age greater than 60 years, poor grade of tumor, and involvement of the facial nerve were three significant variables associated with poor outcome. A superior 5-year actuarial local control was achieved with surgery plus postoperative radiotherapy (54%) compared to other treatment approaches. Based on the results from this review, we would continue to recommend a combined modality approach of surgery followed by postoperative radiotherapy in the management of this rare, but life-threatening disease.

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