Carcinosarcoma (malignant mixed tumor) of the parotid: Report of a case with a pure rhabdomyosarcoma component
Article first published online: 18 JUL 2006
Copyright © 1994 Wiley Periodicals, Inc., A Wiley Company
Head & Neck
Volume 16, Issue 4, pages 379–382, July/August 1994
How to Cite
Gandour-Edwards, R. F., Donald, P. J., Vogt, P. J., Munn, R. and Min, K.-W. (1994), Carcinosarcoma (malignant mixed tumor) of the parotid: Report of a case with a pure rhabdomyosarcoma component. Head Neck, 16: 379–382. doi: 10.1002/hed.2880160414
- Issue published online: 18 JUL 2006
- Article first published online: 18 JUL 2006
- Manuscript Accepted: 26 OCT 1993
Background. Carcinosarcoma or true malignant mixed tumor of the parotid gland is extremely rare, accounting for <1% of all salivary gland malignancies.
Methods. A 63-year-old woman presented with a 5-cm right parotid mass which was resected with a radical parotidectomy and infratemporal fossa dissection.
Results. The tumor contained two distinctive histologic patterns, that of a poorly differentiated ductal carcinoma and a pleomorphic rhabdomyosarcoma. Additionally, a residual focus of pleomorphic adenoma was present peripherally, Immunohistochemical and electron microscopic studies confirmed the skeletal muscle differentiation.
Conclusions. The pattern of combined rhabdomyosarcoma and ductal carcinoma has not been previously reported and adds further evidence to the myoepithelial derivation of these tumors. © 1994 John Wiley & Sons, Inc.