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Article
Hemodynamic Changes in Patients with Portal Venous Obstruction
Article first published online: 21 SEP 2007
DOI: 10.1002/hep.1840030412
Copyright © 1983 American Association for the Study of Liver Diseases
1527-3350/asset/cover.gif?v=1&s=3cd983af6575c8dbfd6b47a63ffa95415ace15f8 "Hepatology")
Additional Information
How to Cite
Lebrec, D., Bataille, C., Bercoff, E. and Valla, D. (1983), Hemodynamic Changes in Patients with Portal Venous Obstruction. Hepatology, 3: 550–553. doi: 10.1002/hep.1840030412
Publication History
- Issue published online: 21 SEP 2007
- Article first published online: 21 SEP 2007
- Manuscript Accepted: 18 MAR 1983
- Manuscript Received: 27 DEC 1982
- Abstract
- References
- Cited By
Abstract
Splanchnic and systemic hemodynamics were evaluated in five adult patients with portal hypertension due to portal venous obstruction and were compared with those of patients with cirrhosis and those of a control group. In patients with portal venous obstruction, the gradient between wedged and free hepatic venous pressures ranged from 2 to 3 mm Hg, as in the control group, and was significantly lower than in patients with cirrhosis. Hepatic blood flow averaged 0.521 ± 0.127 liter per min per m2 (mean ± S.D.) and was significantly lower than that measured in cirrhotic and normal patients. Cardiac index averaged 3.788 ± 0.629 liters per min per m2; this high value for cardiac index was not significantly different from that measured in cirrhotic patients, but was significantly higher than in patients of the control group.
It is suggested that a hyperkinetic circulatory state may result from the development of portal-systemic venous collateral circulation in patients with portal venous obstruction having normal liver and hepatic venous pressures