A population study on the prevalence of gallstone disease: The sirmione study

Authors

  • Luigi Barbara,

    1. Clinica Medica I, Universitá di Bologna, Bologna, Italy and Divisione di Medicina Generale, Ospedale di Desenzano, Desenzano, Italy
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  • Claudia Sama M.D.,

    Corresponding author
    1. Clinica Medica I, Universitá di Bologna, Bologna, Italy and Divisione di Medicina Generale, Ospedale di Desenzano, Desenzano, Italy
    • Clinica Medica I, Policlinico S. Orsola, v. G. Massarenti 9, I-40138 Bologna, Italy
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  • Antonio Maria Morselli Labate,

    1. Clinica Medica I, Universitá di Bologna, Bologna, Italy and Divisione di Medicina Generale, Ospedale di Desenzano, Desenzano, Italy
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  • Francesco Taroni,

    1. Clinica Medica I, Universitá di Bologna, Bologna, Italy and Divisione di Medicina Generale, Ospedale di Desenzano, Desenzano, Italy
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  • Anna Giulia Rusticali,

    1. Clinica Medica I, Universitá di Bologna, Bologna, Italy and Divisione di Medicina Generale, Ospedale di Desenzano, Desenzano, Italy
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  • Davide Festi,

    1. Clinica Medica I, Universitá di Bologna, Bologna, Italy and Divisione di Medicina Generale, Ospedale di Desenzano, Desenzano, Italy
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  • Carlo Sapio,

    1. Clinica Medica I, Universitá di Bologna, Bologna, Italy and Divisione di Medicina Generale, Ospedale di Desenzano, Desenzano, Italy
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  • Enrico Roda,

    1. Clinica Medica I, Universitá di Bologna, Bologna, Italy and Divisione di Medicina Generale, Ospedale di Desenzano, Desenzano, Italy
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  • Claudio Banterle,

    1. Clinica Medica I, Universitá di Bologna, Bologna, Italy and Divisione di Medicina Generale, Ospedale di Desenzano, Desenzano, Italy
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  • Armando Puci,

    1. Clinica Medica I, Universitá di Bologna, Bologna, Italy and Divisione di Medicina Generale, Ospedale di Desenzano, Desenzano, Italy
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  • Franco Formentini,

    1. Clinica Medica I, Universitá di Bologna, Bologna, Italy and Divisione di Medicina Generale, Ospedale di Desenzano, Desenzano, Italy
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  • Silvia Colasanti,

    1. Clinica Medica I, Universitá di Bologna, Bologna, Italy and Divisione di Medicina Generale, Ospedale di Desenzano, Desenzano, Italy
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  • Francesco Nardin

    1. Clinica Medica I, Universitá di Bologna, Bologna, Italy and Divisione di Medicina Generale, Ospedale di Desenzano, Desenzano, Italy
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Abstract

The prevalence of gallstone disease (cholelithiasis and previous cholecystectomy for gallstones) in the population of the town of Sirmione, Italy, examined by ultrasonography, was 6.7% in men and 14.6% in women, ranging from 18 to 65 yr of age (overall prevalence = 11%). The prevalence of cholelithiasis in the same age span was 6.9% (4.5% in men and 8.9% in women). Prevalence of cholelithiasis increased with age in both sexes.

Twenty-two percent of gallstone subjects suffered from biliary pain vs. 2% of subjects without gallstones. No difference was observed in the frequency of nonspecific symptoms between subjects with and without gallstones. Of the 132 gallstone subjects, 108 (82%) were not aware of having gallstones prior to the study.

Prevalence of gallstone disease was found to be higher in obese and hypertriglyceridemic subjects and to increase with the number of pregnancies.

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