Acute non-B hepatitis in the Israel defence forces: Comparison of some epidemiologic features before and after the usage of preexposure immune serum globulin prophylaxis

Authors

  • Haim Matzkin

    Corresponding author
    1. Epidemiology, Army Health Branch, Medical Corps, Israel Defence Force, Tel Aviv, Israel
    Current affiliation:
    1. Urology Ward, Tel Aviv Medical Center, Ichilov Hospital, 6 Weitzman Street, Tel Aviv, Israel
    • Epidemiology, Army Health Branch, Medical Corps, Israel Defence Force, Tel Aviv, Israel
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Abstract

Large-scale epidemics of non-B (HBsAg-negative) hepatitis have occurred in the Israel Defense Forces prior to post- and preexposure immune serum globulin administration. Presently, hepatitis morbidity rates have stabilized around 1 to 2 per 1,000. Several years after vaccine initiation, a comparison of epidemiological features was made in order to redefine risk groups. Seasonal morbidity, sex, ethnic origin and educational status (as a representative of socioeconomic level) were not different after the preexposure immunization compared to the preimmunization era. Therefore, a more selective immunization is proposed.

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