Incidence of parenchymal liver diseases in Denmark, 1981 to 1985: Analysis of hospitalization registry data


  • Thomas P. Almdal,

    1. Department of Medicine A, Division of Hepatology, Rigshospitalet, DK 2100 Copenhagen, Denmark
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  • Professor Thorkild I. A. Sørensen

    Corresponding author
    1. Department of Medicine, Division of Hepatology, Hvidovre University Hospital, DK 2650 Copenhagen, Denmark
    • Department of Medicine 259, Division of Hepatology, Hvidovre Hospital, DK 2650 Copenhagen, Denmark
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The sex-specific and age-specific incidence rates of the major parenchymal liver diseases in a North European population were estimated using a computerized registry of all admissions to somatic hospitals in Denmark.

The incidence was calculated by counting all incident cases of these diseases reported to the registry in the 5-yr period 1981 to 1985 and dividing the number of cases by the number of person-years at risk in this period.

The incidence rates (per million person-years) were for men and women, respectively: infectious hepatitis, 109 and 71; toxic hepatitis, 19 and 22; chronic hepatitis, 27 and 29; alcoholic cirrhosis, 190 and 85; nonalcoholic nonbiliary cirrhosis, 110 and 82; primary biliary cirrhosis, 4 and 14. The pattern of the age-specific incidence rates was similar in men and women in infectious hepatitis, alcoholic cirrhosis, nonalcoholic nonbiliary cirrhosis and primary biliary cirrhosis. Toxic and chronic hepatitis had a higher incidence in women than in men only in older age groups. The incidence of idiopathic hemochromatosis, Wilson's disease, secondary biliary cirrhosis, portal vein thrombosis and Budd-Chiari's syndrome were less than four in both sexes. (HEPATOLOGY 1991;13:650–655.)