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Abstract

Because of its importance as an indication for liver transplantation, the epidemiology of chronic hepatitis B disease is presented. Current knowledge relative to the pathobiological mechanisms of hepatitis B virus—related liver disease are presented, followed by a discussion of the treatment modalities currently available for use in hepatitis B virus—related liver disease. This is followed by an examination of their use in both potential transplant recipients and those who have been given liver transplants for hepatitis B virus disease. Finally, a summary of the current status of hepatitis B virus disease and liver transplantation is presented. (Hepatology 1994;20:20S–23S.)