Landmarks in Hepatology

You have full text access to this OnlineOpen article

Not too little, not too much, but just right

  1. Adrian Reuben M.B.B.S., F.R.C.P.

Article first published online: 7 MAR 2007

DOI: 10.1002/hep.1840360636

Issue

Hepatology

Hepatology

Volume 36, Issue 6, pages 1555–1558, December 2002

Additional Information

How to Cite

Reuben, A. (2002), Not too little, not too much, but just right. Hepatology, 36: 1555–1558. doi: 10.1002/hep.1840360636

Author Information

  1. Professor of Medicine Division of Gastroenterology and Hepatology Department of Medicine Medical University of South Carolina Charleston, SC

Publication History

  1. Issue published online: 7 MAR 2007
  2. Article first published online: 7 MAR 2007

SEARCH

SEARCH BY CITATION

ARTICLE TOOLS

Get PDF (486K)

Reference

  • 1
    Twedt DC, Sternlieb I, Gilberson S. Clinical, morphologic and chemical studies on copper toxicosis of Bedlington terriers. J Amer Vet Med Assoc 1979; 175: 265–275.
  • 2
    Li Y. Abnormal hepatic copper accumulation and its significance in LEC rats developing spontaneous hepatitis and hepatoma. Hokkaido Igaku Zasshi 1991; 66: 658–664.
  • 3
    Molnar JJ. Copper storage in the liver of the wild mute swan (Cynus olor). Arch Pathol Lab Med 1983; 107: 629–632.
  • 4
    Goldfischer S, Schiller B, Sternlieb I. Copper in hepatocyte lysosomes of the toad Bufo marinus L. Nature 1970; 228: 172–173.
  • 5
    Biempica L, Rauch H. Quintana N, Sternlieb I. Morphologic and chemical studies on a murine mutation (toxic Milk Mice) resulting in copper toxicosis. Lab Invest 1988; 59: 500–508.
  • 6
    Wilson SAK. Progressive lenticular degeneration: A familial nervous disease associated with cirrhosis of the liver. Brain 1912; 34: 295–509.
  • 7
    Hoogenraad T. In: Major Problems in Neurology: (30) Wilson's Disease. Chapter 4. Pathology. London: Saunders, 1996: 45–70.
  • 8
    Haymaker W. Kinnier Wilson. In: HaymakerW, SchillerF, eds. The Founders of Neurology. 2nd edition. Springfield, IL: Charles C. Thomas, 1970: 535–539.
  • 9
    Hall HC. La Dégénérescence Hépato-lenticulaire. Maladie de Wilson-Pseudosclérose. Paris: Masson et Cie, 1921.
  • 10
    Bearn AG. A genetical analysis of thirty families with Wilson's disease (hepatolenticular degeneration). Ann Hum Genet 1960; 24: 33–43.
    Direct Link:
  • 11
    Spielmeyer W. Die histopathologische zusammengehörigkeit der Wilsonschen Krankheit und der pseudosklerose. Z Ges Neurol Psychiat 1920; 57: 812–351.
  • 12
    Kayser B. Über einen fall von angeborener grünlicher verfärbung der cornea. Klin Monatsbl Augenh 1902; 40: 22–25.
  • 13
    Fleischer B. Die periphere braun-grunliche horn haurverfärbung, als symptom einer eigenartigen allgemeinerkrankung. Münch Med Wochenschr 1909; 56: 1120–1123.
  • 14
    Wiebers DO, Hollenhorst RW, Goldstein ND. The ophthalmologic manifestations of Wilson's diease. Mayo Clin Proc 1977; 52: 409–416.
  • 15
    Rumpel A. Ueber das Wesen und die Bedeutung der Leberveränderungen und der Pigmentierungen bei den damit verbundenen Fällen von Pseudosklerose, Zugleich ein Beitrag zur Lehre von der Pseudosklerose (Westphal-Strumpell). Dtsch Z Nervenheilk 1913; 49: 54–73.
  • 16
    Cummings JN. The copper and iron content of brain and liver in the normal and in hepatolenticular degeneration. Brain 1948; 71: 410–415.
  • 17
    Policard A, Bonner P, Bonamour G. Etude histospectrographique de l'anneau cornéen de Kayser-Fleischer. CR Soc Biol (Paris) 1936; 122: 1120–1122.
  • 18
    Mandelbrote BM, Stanier MW, Thompson RHS, Thruston MN. Studies on copper metabolism in demyelinating diseases of the central nervous system. Brain 1948; 71: 212–228.
  • 19
    Cummings JN. The effects of B.A.L. in hepatolenticular degeneration. Brain 1951; 74: 10–22.
  • 20
    Walshe, JM. Penicillamine. A new oral therapy for Wilson's disease. Am J Med 1956; 21: 487–495.
  • 21
    Ferenci P. Wilson's disease. Clin Liver Dis 1998; 2: 31–49.
  • 22
    Schilsky ML. Wilson's disease. Clin Persp Gastroenterol 2002; July/August: 234–243.
  • 23
    Gaubius HD. Luna fixata Ludemanni. In: Adversorium varii argumenti. Leiden: Luchtmans, 1771.
  • 24
    Schouwink G. De hepatocerebrale degeneratie, met een onderzoek naar de zinkstofwisseling. University of Amsterdam: MD Thesis 1961.
  • 25
    Yuzbasiyan—Gunkan V, Brewer GJ, Abrams GD, Main B, Glacherio D. Treatment of Wilson's disease with zinc. V. Changes in serum levels of lipase, amylase, and alkaline phosphatase in Wilson's disease patients. J Lab Clin Med 1989; 114: 520–526.
  • 26
    Editor's Choice: Wilson's disease. N Engl J Med 1968; 278: 392–393.
  • 27
    Scheinberg H, Gitlin D. Deficiency of ceruloplasmin in patients with hepatolenticular degeneration (Wilson's disease). Science 1952; 116: 484–485.
  • 28
    Loudianos G, Gitlin JD. Wilson's Disease. Semin Liver Dis 2000; 20: 353–364.
  • 29
    Bull PC, Thomas GR, Rommens JM, Forbes JR, Cox DW. The Wilson's disease gene is a putative copper transporting P-type ATPase similar to the Menkes gene. Nat Genet 1993; 5: 327–337.
  • 30
    Tanzi RE, Petrukhin K, Chernov I, Pellequer JL, Wasco W, et al. The Wilson's disease gene is a copper transporting ATPase with homology to the Menkes disease gene. Nat Genet 1993; 5: 344–350.
  • 31
    Yamaguchi Y, Heiny ME, Gitlin JD. Isolation and characterization of a human liver cDNA as a candidate gene for Wilson's disease. Biochem Biophys Res Commun 1993; 197: 271–277.
  • 32
    Riordan SM, Williams R. The Wilson's diséase gene and phenotype diversity. J Hepatol 2001; 34: 165–171.
  • 33
    Theophilos MB, Cox DW, Mercer JF. The toxic milk mouse is a murine model of Wilson disease. Hum Mol Genet 1996; 5: 1619–1624.
  • 34
    Wu J, Forbes JR, Chen HS, Cox DW. The LEC rat has a deletion in the copper transporting ATPase gene homologous to the Wilson disease gene. Nat Genet 1994; 7: 541–545.
  • 35
    Haywood S. Fuentealba IC, Kemp SJ, Trafford J. Copper toxicosis in the Bedlington terrier: a diagnostic diemma. J Small Anim Pract 2001; 42: 181–185.
    Direct Link:
  • 36
    Fredericq L. Recherches Sur la physiologie du Pouple commun (Octopus vulgaris). Arch Zool Exp Gen 1878; 7: 535–583.
  • 37
    Menkes JH, Alter M, Steigleder GK, Weakley DR, Sung JH. A sex-linked recessive disorder with retardation of growth, peculiar hair and focal cerebral and cerebellar degeneration. Pediatrics 1962; 29: 764–779.
  • 38
    Yarze JC, Martin P, Munoz S, Friedman LS. Wilson's disease: current status. Am J Med 1992; 92: 643–654.
  • 39
    Linder MC. Other trace elements and the liver. Semin Liver Dis 1984; 4: 264–276.
  • 40
    Walshe JM. Copper: not too little, not too much but just right. J R Coll Physicians 1995; 20: 280–288.
  • 41
    McGee HJ, Long SR, Briggs WR. Why whip egg whites in copper bowls. Nature 1984; 308: 667–668.
Get PDF (486K)