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Concise Review in Mechanisms of Disease
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Bacterial translocation (BT) in cirrhosis†
Article first published online: 18 FEB 2005
DOI: 10.1002/hep.20632
Copyright © 2005 American Association for the Study of Liver Diseases
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Wiest, R. and Garcia-Tsao, G. (2005), Bacterial translocation (BT) in cirrhosis. Hepatology, 41: 422–433. doi: 10.1002/hep.20632
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Publication History
- Issue published online: 22 FEB 2005
- Article first published online: 18 FEB 2005
- Manuscript Accepted: 18 JAN 2005
- Manuscript Received: 30 SEP 2004
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- 1, , , , , , , , , , Acute phase proteins in the diagnosis and prediction of cirrhosis associated bacterial infections, Liver International, 2012, 32, 4Direct Link:
- 2, , , , , , , , , , , , Altered intestinal tight junctions’ expression in patients with liver cirrhosis: a pathogenetic mechanism of intestinal hyperpermeability, European Journal of Clinical Investigation, 2012, 42, 4Direct Link:
- 3, , , , , , , Bacterial infections in cirrhosis: role of proton pump inhibitors and intestinal permeability, European Journal of Clinical Investigation, 2012, 42, 6Direct Link:
- 4, , Bacterial resistance in cirrhotic patients: An emerging reality, Journal of Hepatology, 2012, 56, 4, 756
- 5, , , , , Bacterial translocation and changes in the intestinal microbiome in mouse models of liver disease, Journal of Hepatology, 2012, 56, 6, 1283
- 6, , Bases fisiopatológicas del uso de la albúmina humana en la cirrosis hepática, GastroenterologÃa y HepatologÃa, 2012, 35, 1, 42
- 7, , , , , , , Changes of gut bacteria and immune parameters in liver transplant recipients, Hepatobiliary & Pancreatic Diseases International, 2012, 11, 1, 40
- 8, , , , , , , , , Comparison of the Gut Microbe Profiles and Numbers Between Patients with Liver Cirrhosis and Healthy Individuals, Current Microbiology, 2012, 65, 1, 7
- 9, , , , , , , , , , , , , , Effects of pentoxifylline on intestinal bacterial overgrowth, bacterial translocation and spontaneous bacterial peritonitis in cirrhotic rats with ascites, Digestive and Liver Disease, 2012, 44, 3, 239
- 10, , , , Gut Bacterial Translocation Contributes to Microinflammation in Experimental Uremia, Digestive Diseases and Sciences, 2012,
- 11, , Gut microbiome and intestinal barrier failure – The “Achilles heel†in hepatology?, Journal of Hepatology, 2012, 56, 6, 1221
- 12
- 13, , Hepatorenal Syndrome: A Severe, but Treatable, Cause of Kidney Failure in Cirrhosis, American Journal of Kidney Diseases, 2012, 59, 6, 874
- 14, , , , Increased IgA and IgM responses against gut commensals in chronic depression: Further evidence for increased bacterial translocation or leaky gut, Journal of Affective Disorders, 2012,
- 15, , , , , , , , , Intestinal bacterial translocation in rats with cirrhosis is related to compromised paneth cell antimicrobial host defense, Hepatology, 2012, 55, 4Direct Link:
- 16
- 17, , Mechanistic explanations how cell-mediated immune activation, inflammation and oxidative and nitrosative stress pathways and their sequels and concomitants play a role in the pathophysiology of unipolar depression, Neuroscience & Biobehavioral Reviews, 2012, 36, 2, 764
- 18, , , , , Mycobacterial peritonitis: difference between non-tuberculous mycobacteria and Mycobacterium tuberculosis, Clinical Microbiology and Infection, 2012, 18, 3Direct Link:
- 19, , , , , , , Predictive Value of the Model of End-Stage Liver Disease in Cirrhotic Patients with and without Spontaneous Bacterial Peritonitis, Gastroenterology Research and Practice, 2012, 2012, 1
- 20, , , , , , , , , , , , , , , , Promotion of Hepatocellular Carcinoma by the Intestinal Microbiota and TLR4, Cancer Cell, 2012, 21, 4, 504
- 21, , , , Spontan bakterielle Peritonitis, Medizinische Klinik - Intensivmedizin und Notfallmedizin, 2012,
- 22, , Susceptibility to spontaneous bacterial peritonitis - are genetics the future?, Liver International, 2012, 32, 2Direct Link:
- 23
- 24
- 25, , , Bêtabloquants dans l’hypertension portale : des restrictions inattendues !, La Presse Médicale, 2011, 40, 3, 227
- 26, , , Bench-to-beside review: Acute-on-chronic liver failure - linking the gut, liver and systemic circulation, Critical Care, 2011, 15, 5, 233
- 27, , , , , , Circulating nitric oxide products do not solely reflect nitric oxide release in cirrhosis and portal hypertension, Liver International, 2011, 31, 9Direct Link:
- 28, , , , , , , , , , , Diagnostic accuracy of a 16S ribosomal DNA gene-based molecular technique (RT-PCR, microarray, and sequencing) for bacterial meningitis, early-onset neonatal sepsis, and spontaneous bacterial peritonitis, Diagnostic Microbiology and Infectious Disease, 2011, 69, 2, 153
- 29, , , , , , , Endotoxin and tumor necrosis factor-receptor levels in portal and hepatic vein of patients with alcoholic liver cirrhosis receiving elective transjugular intrahepatic portosystemic shunt, European Journal of Gastroenterology & Hepatology, 2011, 23, 12, 1218
- 30, , , , , , , , , , Enteric dysbiosis associated with a mouse model of alcoholic liver disease, Hepatology, 2011, 53, 1Direct Link:
- 31, , , , , , , , Fecal calprotectin is a useful screening parameter for hepatic encephalopathy and spontaneous bacterial peritonitis in cirrhosis, Liver International, 2011, 31, 9Direct Link:
- 32, , , , , , , , Gut microbiota and probiotics in chronic liver diseases, Digestive and Liver Disease, 2011, 43, 6, 431
- 33, , , Immune Dysfunction and Infections in Patients With Cirrhosis, Clinical Gastroenterology and Hepatology, 2011, 9, 9, 727
- 34
- 35, , , , , , , , Mechanical intestinal cleansing and antibiotic prophylaxis for preventing bacterial translocation during the pringle maneuver in rabbits, Surgery Today, 2011, 41, 6, 824
- 36, , , , , , , , , , , , , Phenotypic polymorphism of haptoglobin: A novel risk factor for the development of infection in liver cirrhosis, Human Immunology, 2011, 72, 4, 348
- 37, , , , , Probiotics as an emerging therapeutic strategy to treat NAFLD: focus on molecular and biochemical mechanisms, The Journal of Nutritional Biochemistry, 2011, 22, 8, 699
- 38, , , , , , , , Procalcitonin as a Biomarker for Bacterial Infections in Patients With Liver Cirrhosis in the Emergency Department, Academic Emergency Medicine, 2011, 18, 2Direct Link:
- 39, , , Serologic Antiglycan Antibodies in Inflammatory Bowel Disease, The American Journal of Gastroenterology, 2011, 106, 3, 406
- 40, , , , , The augmented neutrophil respiratory burst in response to Escherichia coli is reduced in liver cirrhosis during infection, Clinical & Experimental Immunology, 2011, 164, 3Direct Link:
- 41, , , , , , , , , , , , The transhepatic endotoxin gradient is present despite liver cirrhosis and is attenuated after transjugular portosystemic shunt (TIPS)., BMC Gastroenterology, 2011, 11, 1, 107
- 42, , , , , , , , , , , Toll-like receptor (TLR) 2 promoter and intron 2 polymorphisms are associated with increased risk for spontaneous bacterial peritonitis in liver cirrhosis, Journal of Hepatology, 2011, 55, 5, 1010
- 43
- 44, , , , , Alcohol takes the toll on immune function, Liver International, 2010, 30, 7Direct Link:
- 45, Ascites, Hepatorenal Syndrome and Spontaneous Bacterial Peritonitis in Patients with Portal Hypertension, The Korean Journal of Gastroenterology, 2010, 56, 3, 168
- 46, , , , , , , , , , , , , , Attenuation of toll-like receptor 2-mediated innate immune response in patients with alcoholic chronic liver disease, Liver International, 2010, 30, 7Direct Link:
- 47, , , , , , , , , , Bacterial Translocation in a Rat Model of Large Volume Hepatic Radiofrequency Ablation, Journal of Surgical Research, 2010, 161, 2, 250
- 48
- 49, , Insuficiencia hepática crónica: una entidad clÃnica necesitada de investigadores, GastroenterologÃa y HepatologÃa, 2010, 33, 9, 619
- 50, , , , , , , , Intestinal flora imbalance results in altered bacterial translocation and liver function in rats with experimental cirrhosis, European Journal of Gastroenterology & Hepatology, 2010, 1
- 51, , , , , , , , , Is detection of bacterial DNA in ascitic fluid of clinical relevance?, European Journal of Gastroenterology & Hepatology, 2010, 22, 12, 1487
- 52, , Management of Refractory Ascites and Hepatorenal Syndrome, Current Gastroenterology Reports, 2010, 13, 1, 17
- 53, , , , , , , , , , , , , , , Neutrophil Migration During Liver Injury Is Under Nucleotide-Binding Oligomerization Domain 1 Control, Gastroenterology, 2010, 138, 4, 1546
- 54, , , , , , Nucleotide-binding oligomerization domain containing 2 (NOD2) variants are genetic risk factors for death and spontaneous bacterial peritonitis in liver cirrhosis, Hepatology, 2010, 51, 4Direct Link:
- 55, , , , , , , Pringle Maneuver Deteriorates Gut Barrier Dysfunction Induced by Extended-Liver Radiofrequency Ablation, Digestive Diseases and Sciences, 2010, 56, 5, 1548
- 56, , , , Problemas actuales en la prevención y tratamiento de las infecciones en pacientes con cirrosis, GastroenterologÃa y HepatologÃa, 2010, 33, 10, 729
- 57, , , , , , , , , Proteomic evidence of bacterial peptide translocation in afebrile patients with cirrhosis and ascites, Journal of Molecular Medicine, 2010, 88, 5, 487
- 58, , Renal and circulatory dysfunction in cirrhosis: Current management and future perspectives, Journal of Hepatology, 2010, 53, 6, 1135
- 59, , Spontan bakterielle Peritonitis bei Leberzirrhose, Intensivmedizin und Notfallmedizin, 2010, 47, 8, 571
- 60, , , The impact of nutrition on cirrhotic patients awaiting liver transplantation, Current Opinion in Clinical Nutrition and Metabolic Care, 2010, 13, 5, 554
- 61, , , , The role of lipopolysaccharide/toll-like receptor 4 signaling in chronic liver diseases, Hepatology International, 2010, 4, 4, 659
- 62
- 63
- 64, , , , , , , , Association Between Small Intestinal Bacterial Overgrowth and Peripheral Bacterial DNA in Cirrhotic Patients, Digestive Diseases and Sciences, 2009, 55, 5, 1465
- 65, , , , , , , Clinical characteristics and outcomes of pneumococcal bacteremia in adult patients with liver cirrhosis, Diagnostic Microbiology and Infectious Disease, 2009, 63, 2, 160
- 66, , , , , , , , , , , , , , , , , Clinical Features and Prognosis of Spontaneous Bacterial Peritonitis in Korean Patients with Liver Cirrhosis: A Multicenter Retrospective Study, Gut and Liver, 2009, 3, 3, 197
- 67
- 68, , , , , , , , , , Impact of liver cirrhosis on mortality in patients with community-acquired bacteremia, Diagnostic Microbiology and Infectious Disease, 2009, 64, 2, 124
- 69, , , , , , , , , , Increased Plasma Carbon Monoxide in Patients With Viral Cirrhosis and Hyperdynamic Circulation, The American Journal of Gastroenterology, 2009, 104, 4, 891
- 70, , , , , , , , , , , , Intestinal Permeability in Cirrhotic Patients With and Without Spontaneous Bacterial Peritonitis: Is the Ring Closed?, The American Journal of Gastroenterology, 2009, 105, 2, 323
- 71, , , , , , , , , , Low serum concentration of apolipoprotein A-I is an indicator of poor prognosis in cirrhotic patients with severe sepsis, Journal of Hepatology, 2009, 50, 5, 906
- 72
- 73
- 74
- You have free access to this content75, , , Small-intestinal bacterial overgrowth in cirrhosis is related to the severity of liver disease, Alimentary Pharmacology & Therapeutics, 2009, 29, 12Direct Link:
- 76, , , , Störungen des angeborenen Immunsystems bei akuten und chronischen Lebererkrankungen, Wiener klinische Wochenschrift, 2009, 121, 23-24, 732
- 77
- 78, , , , , , , , A TLR4/MD2 fusion protein inhibits LPS-induced pro-inflammatory signaling in hepatic stellate cells, Biochemical and Biophysical Research Communications, 2008, 375, 2, 210
- 79, , , , , , , , , , Bacterial DNA in patients with cirrhosis and noninfected ascites mimics the soluble immune response established in patients with spontaneous bacterial peritonitis, Hepatology, 2008, 47, 3Direct Link:
- 80
- 81, , , , , , Effect of probiotic treatment on deranged neutrophil function and cytokine responses in patients with compensated alcoholic cirrhosis, Journal of Hepatology, 2008, 48, 6, 945
- 82, , Evaluation and Management of End-Stage Liver Disease in Children, Gastroenterology, 2008, 134, 6, 1741
- 83, Is bacterial DNA a surrogate marker of bacterial translocation in cirrhosis?, Journal of Hepatology, 2008, 49, 1, 145
- 84, , Nutrition in End-Stage Liver Disease: Principles and Practice, Gastroenterology, 2008, 134, 6, 1729
- 85, , , Pathogenetic background for treatment of ascites and hepatorenal syndrome, Hepatology International, 2008, 2, 4, 416
- 86
- 87, , Probiotics and Liver Disease, Journal of Clinical Gastroenterology, 2008, 42, Supplement 2, S80
- 88, , Probiotics: where are they going next? New and emerging areas of research, Nutrition Bulletin, 2008, 33, 4Direct Link:
- 89, , Toll-like receptors and adaptor molecules in liver disease: Update, Hepatology, 2008, 48, 1Direct Link:
- 90, , , , , , Uncoupling of sympathetic nervous system and hypothalamic-pituitary-adrenal axis in cirrhosis, Journal of Gastroenterology and Hepatology, 2008, 23, 12Direct Link:
- 91
- 92, , , , , , , , , , Bacterial DNA Induces the Complement System Activation in Serum and Ascitic Fluid from Patients with Advanced Cirrhosis, Journal of Clinical Immunology, 2007, 27, 4, 438
- 93, , , Bacterial Infection-Related Morbidity and Mortality in Cirrhosis, The American Journal of Gastroenterology, 2007, 102, 7, 1510
- 94
- 95, , , , , Endotoxemia during liver transplantation, Liver Transplantation, 2007, 13, 11Direct Link:
- 96, , , , , , , , , Epidemiology and outcome of primary community-acquired bacteremia in adult patients, European Journal of Clinical Microbiology & Infectious Diseases, 2007, 26, 7, 453
- 97, , , , INCREASED INTESTINAL ENDOTOXIN ABSORPTION DURING ENTERIC NEMATODE BUT NOT PROTOZOAL INFECTIONS THROUGH A MAST CELL-MEDIATED MECHANISM, Shock, 2007, 1
- 98, , , , Infection et rupture de varice œsophagienne au cours de la cirrhose, Gastroentérologie Clinique et Biologique, 2007, 31, 1, 27
- 99, , Infections in Patients With End-stage Liver Disease, Journal of Clinical Gastroenterology, 2007, 41, 4, 403
- 100, , , , , Intestinal barrier dysfunction in developing liver cirrhosis: An in vivo analysis of bacterial translocation, Hepatology Research, 2007, 37, 1Direct Link:
- 101, , Microbiological Characteristics of Spontaneous Bacterial Peritonitis in Korea, The Korean Journal of Hepatology, 2007, 13, 3, 304
- 102, Pathogenesis of hepatic encephalopathy: the tumour necrosis factor-α theory, European Journal of Clinical Investigation, 2007, 37, 4Direct Link:
- 103, , Probiotiques Et Autres Pathologies Digestives : Perspectives, Cahiers de Nutrition et de Diététique, 2007, 42, 60
- 104, Relationship between circulating levels of tumour necrosis factor-α and Child–Pugh scores in liver cirrhosis, International Journal of Clinical Practice, 2007, 61, 3Direct Link:
- 105
- 106, , , , , , , , , , Adrenal insufficiency in patients with cirrhosis, severe sepsis and septic shock, Hepatology, 2006, 43, 4Direct Link:
- 107, , , , Endogenous opioids and liver disease, Scandinavian Journal of Gastroenterology, 2006, 41, 1, 1
- 108, , , , , Hypertonic saline enhances host defense to bacterial challenge by augmenting Toll-like receptors*, Critical Care Medicine, 2006, 34, 6, 1758
- 109
- 110, , , , , , , , , , , , , The detection of bacterial DNA in blood of rats with CCl4-induced cirrhosis with ascites represents episodes of bacterial translocation, Hepatology, 2006, 44, 3Direct Link:
- 111, , The intestinal flora and bacterial infection in cirrhosis, Journal of Hepatology, 2006, 45, 5, 744
- 112, , The management of severe alcoholic liver disease and variceal bleeding in the intensive care unit, Current Opinion in Internal Medicine, 2006, 5, 3, 276
- 113
- 114, , Bacterial Infections in Patients with Cirrhosis, Journal of the Chinese Medical Association, 2005, 68, 10, 447