SEARCH

SEARCH BY CITATION

Cited in:

CrossRef

This article has been cited by:

  1. 1
    M Biffen, H Matsui, S Edwards, AJ Leishman, K Eiho, E Holness, G Satterthwaite, I Doyle, H Wada, NJ Fraser, SL Hawkins, M Aoki, H Tomizawa, AD Benjamin, H Takaku, T McInally, CM Murray, Biological characterization of a novel class of toll-like receptor 7 agonists designed to have reduced systemic activity, British Journal of Pharmacology, 2012, 166, 2
  2. 2
    Megan Crane, Kumar Visvanathan, Sharon R. Lewin, HIV Infection and TLR Signalling in the Liver, Gastroenterology Research and Practice, 2012, 2012, 1

    CrossRef

  3. 3
    D. N. Nguyen, K. P. Mahon, G. Chikh, P. Kim, H. Chung, A. P. Vicari, K. T. Love, M. Goldberg, S. Chen, A. M. Krieg, J. Chen, R. Langer, D. G. Anderson, PNAS Plus: Lipid-derived nanoparticles for immunostimulatory RNA adjuvant delivery, Proceedings of the National Academy of Sciences, 2012, 109, 14, E797

    CrossRef

  4. 4
    Xiaoyong Zhang, Anke Kraft, Ruth Broering, Joerg F Schlaak, Ulf Dittmer, Mengji Lu, Preclinical development of TLR ligands as drugs for the treatment of chronic viral infections, Expert Opinion on Drug Discovery, 2012, 1

    CrossRef

  5. 5
    Mona Hedayat, Kiyoshi Takeda, Nima Rezaei, Prophylactic and therapeutic implications of toll-like receptor ligands, Medicinal Research Reviews, 2012, 32, 2
  6. 6
    Christina Schlecker, Alfred Ultsch, Gerd Geisslinger, Jörn Lötsch, The pharmacogenetic background of hepatitis C treatment, Mutation Research/Reviews in Mutation Research, 2012,

    CrossRef

  7. 7
    Giel R. Gaajetaan, Cathrien A. Bruggeman, Frank R Stassen, The type I interferon response during viral infections: a “SWOT” analysis, Reviews in Medical Virology, 2012, 22, 2
  8. 8
    Hannah Perkins, Tansi Khodai, Houria Mechiche, Peter Colman, Frances Burden, Carl Laxton, Nigel Horscroft, Tom Corey, Deborah Rodrigues, Jaiessh Rawal, Jonathan Heyen, Mark Fidock, Mike Westby, Helen Bright, Therapy with TLR7 Agonists Induces Lymphopenia: Correlating Pharmacology to Mechanism in a Mouse Model, Journal of Clinical Immunology, 2012,

    CrossRef

  9. 9
    Hannah M. Jones, Phylinda L. S. Chan, Piet H. van der Graaf, Robert Webster, Use of modelling and simulation techniques to support decision making on the progression of PF-04878691, a TLR7 agonist being developed for hepatitis C, British Journal of Clinical Pharmacology, 2012, 73, 1
  10. 10
    Peter Jones, David C. Pryde, Thien-Duc Tran, Fiona M. Adam, Gerwyn Bish, Frederick Calo, Guiseppe Ciaramella, Rachel Dixon, Jonathan Duckworth, David N.A. Fox, Duncan A. Hay, James Hitchin, Nigel Horscroft, Martin Howard, Carl Laxton, Tanya Parkinson, Gemma Parsons, Katie Proctor, Mya C. Smith, Nicholas Smith, Amy Thomas, Discovery of a highly potent series of TLR7 agonists, Bioorganic & Medicinal Chemistry Letters, 2011, 21, 19, 5939

    CrossRef

  11. 11
    Joseph Ahn, Steven L. Flamm, Hepatitis C Therapy: Other Players in the Game, Clinics in Liver Disease, 2011, 15, 3, 641

    CrossRef

  12. 12
    Michael A. Gelman, Jeffrey S. Glenn, Mixing the right hepatitis C inhibitor cocktail, Trends in Molecular Medicine, 2011, 17, 1, 34

    CrossRef

  13. 13
    J. F. Bergmann, J. de Bruijne, D. M. Hotho, R. J. de Knegt, A. Boonstra, C. J. Weegink, A. A. van Vliet, J. van de Wetering, S. P. Fletcher, L. A. Bauman, M. Rahimy, J. R. Appleman, J. L. Freddo, H. L. A. Janssen, H. W. Reesink, Randomised clinical trial: anti-viral activity of ANA773, an oral inducer of endogenous interferons acting via TLR7, in chronic HCV, Alimentary Pharmacology & Therapeutics, 2011, 34, 4
  14. 14
    Ruth Broering, Mengji Lu, Joerg F. Schlaak, Role of Toll-like receptors in liver health and disease, Clinical Science, 2011, 121, 10, 415

    CrossRef

  15. 15
    Mona Hedayat, Mihai G Netea, Nima Rezaei, Targeting of Toll-like receptors: a decade of progress in combating infectious diseases, The Lancet Infectious Diseases, 2011, 11, 9, 702

    CrossRef

  16. 16
    M D Fidock, B E Souberbielle, C Laxton, J Rawal, O Delpuech-Adams, T P Corey, P Colman, V Kumar, J B Cheng, K Wright, S Srinivasan, K Rana, C Craig, N Horscroft, M Perros, M Westby, R Webster, E van der Ryst, The Innate Immune Response, Clinical Outcomes, and Ex Vivo HCV Antiviral Efficacy of a TLR7 Agonist (PF-4878691), Clinical Pharmacology & Therapeutics, 2011, 89, 6, 821

    CrossRef

  17. 17
    Yongyan Chen, Rui Sun, Toll-like receptors in acute liver injury and regeneration, International Immunopharmacology, 2011, 11, 10, 1433

    CrossRef

  18. 18
    Yasuteru Kondo, Yoshiyuki Ueno, Tooru Shimosegawa, Toll-Like Receptors Signaling Contributes to Immunopathogenesis of HBV Infection, Gastroenterology Research and Practice, 2011, 2011, 1

    CrossRef

  19. 19
    Kai Lin, Development of novel antiviral therapies for hepatitis C virus, Virologica Sinica, 2010, 25, 4, 246

    CrossRef

  20. You have free access to this content20
    Erin F. Nicholls, Laurence Madera, Robert E. W. Hancock, Immunomodulators as adjuvants for vaccines and antimicrobial therapy, Annals of the New York Academy of Sciences, 2010, 1213, 1
  21. 21
    Serena Chang, Karen Kodys, Gyongyi Szabo, Impaired expression and function of toll-like receptor 7 in hepatitis C virus infection in human hepatoma cells, Hepatology, 2010, 51, 1
  22. 22
    Ivan Hirsch, Christophe Caux, Uzma Hasan, Nathalie Bendriss-Vermare, Daniel Olive, Impaired Toll-like receptor 7 and 9 signaling: from chronic viral infections to cancer, Trends in Immunology, 2010, 31, 10, 391

    CrossRef

  23. 23
    Veronica D. Gonzalez, Alan L. Landay, Johan K. Sandberg, Innate immunity and chronic immune activation in HCV/HIV-1 co-infection, Clinical Immunology, 2010, 135, 1, 12

    CrossRef

  24. 24
    Vincent Mallet, Anaïs Vallet-Pichard, Stanislas Pol, New trends in hepatitis C management, La Presse Médicale, 2010, 39, 4, 446

    CrossRef

  25. 25
    Andreas Storek, Olfert Landt, Carola Fleischer, Konstantin Baumann, Ulrich Lass, Ralf R. Schumann, Djin-Ye Oh, Quadruplex Genotyping of TLR-8 Polymorphisms in a Single Reaction, Analytical Letters, 2010, 43, 6, 1066

    CrossRef

  26. 26
    Mohamed L. Salem, Maha EL-Demellawy, Abdel Raouf Abou El-Azm, The potential use of Toll-like receptor agonists to restore the dysfunctional immunity induced by hepatitis C virus, Cellular Immunology, 2010, 262, 2, 96

    CrossRef

  27. 27
    Jan Petrasek, Pranoti Mandrekar, Gyongyi Szabo, Toll-Like Receptors in the Pathogenesis of Alcoholic Liver Disease, Gastroenterology Research and Practice, 2010, 2010, 1

    CrossRef

  28. 28
    Eva Askar, Giuliano Ramadori, Sabine Mihm, Toll-like receptor 7 rs179008/Gln11Leu gene variants in chronic hepatitis C virus infection, Journal of Medical Virology, 2010, 82, 11
  29. 29
    STUART C. RAY, DAVID L. THOMAS, Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases, 2010,

    CrossRef

  30. 30
    Sarah Clarke, Carl Laxton, Nigel Horscroft, Virgile Richard, Amy Thomas, Tanya Parkinson, Comparison of Rat and Human Responses to Toll-Like Receptor 7 Activation, Journal of Interferon & Cytokine Research, 2009, 29, 2, 113

    CrossRef

  31. 31
    Daniel P Webster, Paul Klenerman, Jane Collier, Katie JM Jeffery, Development of novel treatments for hepatitis C, The Lancet Infectious Diseases, 2009, 9, 2, 108

    CrossRef

  32. 32
    Kimberly A. Forde, K. Rajender Reddy, Hepatitis C Virus Infection and Immunomodulatory Therapies, Clinics in Liver Disease, 2009, 13, 3, 391

    CrossRef

  33. 33
    Yi-Liang Zhang, Ying-Jun Guo, Bin Li, Shu-Han Sun, Hepatitis C virus single-stranded RNA induces innate immunity via Toll-like receptor 7, Journal of Hepatology, 2009, 51, 1, 29

    CrossRef

  34. 34
    Yasuteru Kondo, Yoshiyuki Ueno, Tooru Shimosegawa, Immunopathogenesis of hepatitis B persistent infection: implications for immunotherapeutic strategies, Clinical Journal of Gastroenterology, 2009, 2, 2, 71

    CrossRef

  35. You have free access to this content35
    J. De Bruijne, C. J. Weegink, P. L. M. Jansen, H. W. Reesink, New developments in the antiviral treatment of hepatitis C, Vox Sanguinis, 2009, 97, 1
  36. 36
    Naoya Sakamoto, Mamoru Watanabe, New therapeutic approaches to hepatitis C virus, Journal of Gastroenterology, 2009, 44, 7, 643

    CrossRef

  37. 37
    Ilan S. Weisberg, Samuel H. Sigal, Ira M. Jacobson, New treatments for hepatitis C: Life cycle lessons, Current Hepatitis Reports, 2009, 6, 2, 75

    CrossRef

  38. 38
    Naoya Sakamoto, George Y Wu, Prospects for future therapy of HCV infection, Future Virology, 2009, 4, 5, 453

    CrossRef

  39. 39
    Bo Wang, Martin Trippler, Rongjuan Pei, Mengji Lu, Ruth Broering, Guido Gerken, Joerg F. Schlaak, Toll-like receptor activated human and murine hepatic stellate cells are potent regulators of hepatitis C virus replication, Journal of Hepatology, 2009, 51, 6, 1037

    CrossRef

  40. 40
    E. G. Rhee, D. H. Barouch, Translational Mini-Review Series on Vaccines for HIV: Harnessing innate immunity for HIV vaccine development, Clinical & Experimental Immunology, 2009, 157, 2
  41. 41
    E. Schott, H. Witt, K. Neumann, A. Bergk, J. Halangk, V. Weich, T. Müller, G. Puhl, B. Wiedenmann, T. Berg, Association of TLR7 single nucleotide polymorphisms with chronic HCV-infection and response to interferon-a-based therapy, Journal of Viral Hepatitis, 2008, 15, 1
  42. 42
    Thomas Meyer, Eggert Stockfleth, Clinical investigations of Toll-like receptor agonists, Expert Opinion on Investigational Drugs, 2008, 17, 7, 1051

    CrossRef

  43. 43
    Rudolf E Stauber, Harald H Kessler, Drugs in Development for Hepatitis C, Drugs, 2008, 68, 10, 1347

    CrossRef

  44. 44
    Ellen M. Tedaldi, Emerging Therapies for Hepatitis C and HIV in Drug Abusers, Journal of Addictive Diseases, 2008, 27, 2, 83

    CrossRef

  45. 45
    Gyongyi Szabo, Angela Dolganiuc, Hepatitis C and Innate Immunity: Recent Advances, Clinics in Liver Disease, 2008, 12, 3, 675

    CrossRef

  46. 46
    M. Irshad, I. Khushboo, Shiwani Singh, Sukhbir Singh, Hepatitis C Virus (HCV): A Review of Immunological Aspects, International Reviews of Immunology, 2008, 27, 6, 497

    CrossRef

  47. 47
    Krystle Lang, David B Weiner, Immunotherapy for HCV infection: next steps, Expert Review of Vaccines, 2008, 7, 7, 915

    CrossRef

  48. 48
    Dirk G Brockstedt, Thomas W Dubensky, Promises and challenges for the development ofListeria monocytogenes-based immunotherapies, Expert Review of Vaccines, 2008, 7, 7, 1069

    CrossRef

  49. 49
    E. CHOLONGITAS, G. V. PAPATHEODORIDIS, Review article: novel therapeutic options for chronic hepatitis C, Alimentary Pharmacology & Therapeutics, 2008, 27, 10
  50. 50
    Athanasios Katsargyris, Chris Klonaris, Elias Bastounis, Stamatios Theocharis, Toll-like receptor modulation: A novel therapeutic strategy in cardiovascular disease?, Expert Opinion on Therapeutic Targets, 2008, 12, 11, 1329

    CrossRef

  51. 51
    Ekihiro Seki, David A. Brenner, Toll-like receptors and adaptor molecules in liver disease: Update, Hepatology, 2008, 48, 1
  52. 52
    Eckart Schott, Heiko Witt, Konrad Neumann, Stefan Taube, Djin-Ye Oh, Eckart Schreier, Sandra Vierich, Gero Puhl, Alexandra Bergk, Juliane Halangk, Viola Weich, Bertram Wiedenmann, Thomas Berg, A Toll-like receptor 7 single nucleotide polymorphism protects from advanced inflammation and fibrosis in male patients with chronic HCV-infection, Journal of Hepatology, 2007, 47, 2, 203

    CrossRef

  53. 53
    Gyongyi Szabo, Serena Chang, Angela Dolganiuc, Altered innate immunity in chronic hepatitis C infection: Cause or effect?, Hepatology, 2007, 46, 4
  54. 54
    E. Jenny Heathcote, Antiviral therapy: chronic hepatitis C, Journal of Viral Hepatitis, 2007, 14,
  55. 55
    Albert J. Eid, Robert A. Brown, Carlos V. Paya, Raymund R. Razonable, Association Between Toll-Like Receptor Polymorphisms and the Outcome of Liver Transplantation for Chronic Hepatitis C Virus, Transplantation, 2007, 84, 4, 511

    CrossRef

  56. 56
    Dominique Guyader, Comment traiter les malades non répondeurs à la bithérapie antivirale C ?, Gastroentérologie Clinique et Biologique, 2007, 31, 3, 317

    CrossRef

  57. 57
    Francois Romagne, Current and future drugs targeting one class of innate immunity receptors: the Toll-like receptors, Drug Discovery Today, 2007, 12, 1-2, 80

    CrossRef

  58. 58
    Roberto J. Firpi, David R. Nelson, Current and Future Hepatitis C Therapies, Archives of Medical Research, 2007, 38, 6, 678

    CrossRef

  59. 59
    Alan X. Xiang, Stephen E. Webber, Bradley M. Kerr, Erik J. Rueden, Joseph R. Lennox, Gregory J. Haley, Tingmin Wang, John S. Ng, Mark R. Herbert, David L. Clark, Virginia N. Banh, Wei Li, Simon P. Fletcher, Kevin R. Steffy, Darian M. Bartkowski, Leonid I. Kirkovsky, Lisa A. Bauman, Devron R. Averett, Discovery of ANA975: An Oral Prodrug of the TLR-7 Agonist Isatoribine, Nucleosides, Nucleotides and Nucleic Acids, 2007, 26, 6-7, 635

    CrossRef

  60. 60
    Yupeng He, Wei Duan, Seng-Lai Tan, Emerging host cell targets for hepatitis C therapy, Drug Discovery Today, 2007, 12, 5-6, 209

    CrossRef

  61. 61
    Paul J. Pockros, Dominque Guyader, Heather Patton, Myron J. Tong, Terry Wright, John G. McHutchison, Tze-Chiang Meng, Oral resiquimod in chronic HCV infection: Safety and efficacy in 2 placebo-controlled, double-blind phase IIa studies, Journal of Hepatology, 2007, 47, 2, 174

    CrossRef

  62. 62
    Mark A Tomai, Richard L Miller, Kenneth E Lipson, William C Kieper, Isidro E Zarraga, John P Vasilakos, Resiquimod and other immune response modifiers as vaccine adjuvants, Expert Review of Vaccines, 2007, 6, 5, 835

    CrossRef

  63. 63
    Johannes G. Bode, Erwin D. Brenndörfer, Dieter Häussinger, Subversion of innate host antiviral strategies by the hepatitis C virus, Archives of Biochemistry and Biophysics, 2007, 462, 2, 254

    CrossRef

  64. 64
    Seng-Lai Tan, Gopinath Ganji, Bryan Paeper, Sean Proll, Michael G Katze, Systems biology and the host response to viral infection, Nature Biotechnology, 2007, 25, 12, 1383

    CrossRef

  65. 65
    Philip T. Liu, Stephan R. Krutzik, Robert L. Modlin, Therapeutic implications of the TLR and VDR partnership, Trends in Molecular Medicine, 2007, 13, 3, 117

    CrossRef

  66. 66
    Michael Schultheiß, Robert Thimme, Toll like receptor 7 and hepatitis C virus infection, Journal of Hepatology, 2007, 47, 2, 165

    CrossRef

  67. 67
    Ken J. Ishii, Shizuo Akira, Toll or Toll-Free Adjuvant Path Toward the Optimal Vaccine Development, Journal of Clinical Immunology, 2007, 27, 4, 363

    CrossRef

  68. 68
    Angela Meier, Marcus Altfeld, Toll-like receptor signaling in HIV-1 infection: a potential target for therapy?, Expert Review of Anti-infective Therapy, 2007, 5, 3, 323

    CrossRef

  69. 69
    Alex J V Thompson, Stephen A Locarnini, Toll-like receptors, RIG-I-like RNA helicases and the antiviral innate immune response, Immunology and Cell Biology, 2007, 85, 6, 435

    CrossRef

  70. 70
    G. Inchauspé, M. L. Michel, Vaccines and immunotherapies against hepatitis B and hepatitis C viruses, Journal of Viral Hepatitis, 2007, 14,
  71. 71
    Pierluigi Toniutto, Carlo Fabris, Mario Pirisi, Antiviral treatment of hepatitis C, Expert Opinion on Pharmacotherapy, 2006, 7, 15, 2025

    CrossRef

  72. 72
    Asim S. Khokhar, Valerie Byrnes, Nezam H. Afdhal, Future therapies for hepatitis C, Current Hepatitis Reports, 2006, 5, 3, 121

    CrossRef

  73. 73
    Guangyi Jin, Christina C. N. Wu, Dennis A. Carson, Howard B. Cottam, Guanosine analog in the pyrido[2,3-d]pyrimidine ring system As a potential Toll-like receptor agonist, Nucleosides, Nucleotides and Nucleic Acids, 2006, 25, 12, 1391

    CrossRef

  74. 74
    Mark A. Tomai, Richard L. Miller, Kenneth E. Lipson, John P. Vasilakos, Susan L. Woulfe, Immune response modifiers: Imiquimod and future drugs for modulating the immune response, Drug Discovery Today: Therapeutic Strategies, 2006, 3, 3, 343

    CrossRef

  75. 75
    Mouldy Sioud, Innate sensing of self and non-self RNAs by Toll-like receptors, Trends in Molecular Medicine, 2006, 12, 4, 167

    CrossRef

  76. 76
    Laura Waters, Mark Nelson, New therapeutic options for hepatitis C, Current Opinion in Infectious Diseases, 2006, 19, 6, 615

    CrossRef

  77. 77
    Jean-Michel Pawlotsky, Nouvelles stratégies thérapeutiques dans l‘hépatite chronique C, Gastroentérologie Clinique et Biologique, 2006, 30, 8-9, 1009

    CrossRef

  78. 78
    Rudolf E. Stauber, Vanessa Stadlbauer, Novel approaches for therapy of chronic hepatitis C, Journal of Clinical Virology, 2006, 36, 2, 87

    CrossRef

  79. 79
    Lucía Gil-Guerrero, Pablo Sarobe, Jesús Prieto, Nuevos tratamientos para la hepatitis C, Medicina Clínica, 2006, 127, 3, 104

    CrossRef

  80. 80
    Gyongyi Szabo, Angela Dolganiuc, Pranoti Mandrekar, Pattern recognition receptors: A contemporary view on liver diseases, Hepatology, 2006, 44, 2
  81. 81
    P. P. C. Boor, H. J. Metselaar, S. Mancham, H. W. Tilanus, J. G. Kusters, J. Kwekkeboom, Prednisolone Suppresses the Function and Promotes Apoptosis of Plasmacytoid Dendritic Cells, American Journal of Transplantation, 2006, 6, 10
  82. 82
    Stephen J Polyak, Resistance of hepatitis C virus to the host antiviral response, Future Virology, 2006, 1, 1, 89

    CrossRef

  83. 83
    V. V. Sumbayev, I. M. Yasinska, Role of MAP Kinase-Dependent Apoptotic Pathway in Innate Immune Responses and Viral Infection, Scandinavian Journal of Immunology, 2006, 63, 6
  84. 84
    Daniel Yerly, Loriana Di Giammarino, Florian Bihl, Andreas Cerny, Targets of emerging therapies for viral hepatitis B and C, Expert Opinion on Therapeutic Targets, 2006, 10, 6, 833

    CrossRef

  85. 85
    John G. McHutchison, Ralf Bartenschlager, Keyur Patel, Jean-Michel Pawlotsky, The face of future hepatitis C antiviral drug development: Recent biological and virologic advances and their translation to drug development and clinical practice, Journal of Hepatology, 2006, 44, 2, 411

    CrossRef

  86. 86
    Gábor Földes, Stephan von Haehling, Stefan D Anker, Toll-like receptor modulation in cardiovascular disease: a target for intervention?, Expert Opinion on Investigational Drugs, 2006, 15, 8, 857

    CrossRef

  87. 87
    Robert F. Schwabe, Ekihiro Seki, David A. Brenner, Toll-Like Receptor Signaling in the Liver, Gastroenterology, 2006, 130, 6, 1886

    CrossRef