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References

  • 1
    Borst P, Oude Elferink R. Mammalian ABC transporters in health and disease. Annu Rev Biochem 2002; 71: 537592.
  • 2
    Zelcer N, van de Wetering K, Smith A, Scheffer A, Marschall H-U, Wielinga P, et al. Mice lacking Mrp3 (Abcc3) have normal bile acid transport, but display altered hepatic transport of endogenous glucuronides. J Hepatol 2005 (in press).
  • 3
    Scheffer GL, Kool M, de Haas M, de Vree JM, Pijnenborg AC, Bosman DK, et al. Tissue distribution and induction of human multidrug resistant protein 3. Lab Invest 2002; 82: 193201.
  • 4
    Hirohashi T, Suzuki H, Sugiyama Y. Characterization of the transport properties of cloned rat multidrug resistance-associated protein 3 (MRP3). J Biol Chem 1999; 274: 1518115185.
  • 5
    Zelcer N, Saeki T, Bot I, Kuil A, Borst P. Transport of bile acids in multidrug-resistance-protein 3-overexpressing cells co-transfected with the ileal Na+-dependent bile-acid transporter. Biochem J 2003; 369: 2330.
  • 6
    Davidson DGD, Eastham WN. Acute liver necrosis following overdose with paracetamol. Br Med J 1966; 2: 497499.
  • 7
    Clark R, Thompson RPH, Borirakchanyavat V, Widdop B, Davidson AR, Williams R Hepatic damage and death from overdose of paracetamol. Lancet 1973; i: 6670.
  • 8
    Hjelle J, Klaassen CD. Glucuronidation and biliary excretion of acetaminophen in rats. J Pharm Pharmacol 1984; 228: 407413.
  • 9
    Gregus Z, Madhu C, Klaassen CD. Species variation in toxication and detoxification of acetaminophen in vivo: a comparative study of biliary and urinary excretion of acetaminophen metabolites. J Pharmacol Exp Ther 1988; 244: 9199.
  • 10
    Manautou JE, Tveit A, Hoivik DJ, Khairallah EA, Cohen SD. Protection by clofibrate against acetaminophen hepatotoxicity in male CD-1 mice is associated with an early increase in biliary concentration of APAP-GSH adducts. Toxicol Appl Pharmacol 1996; 140: 3038.
  • 11
    Chen C, Hennig GE, Manautou JE. Hepatobiliary excretion of acetaminophen glutathione conjugate and its derivatives in transport-deficient (TR-) hyperbilirubinemic rats. Drug Metab Dispos 2003; 31: 798804.
  • 12
    Xiong H, Turner C, Ward ES, Jansen PLM, Brouwer KLR. Altered hepatobiliary disposition of acetaminophen glucuronide in isolated perfused livers from multidrug resistance-associated protein 2-deficient TR- rats. J Pharmacol Exp Ther 2000; 295: 512518.
  • 13
    Ogawa K, Suzuki H, Hirohashi T, Ishikawa T, Meier PJ, Hirose K, et al. Characterization of inducible nature of MRP3 in rat liver. Am J Physiol 2000; 278: G438G446.
  • 14
    Xiong H, Suzuki H, Sugiyama Y, Meier PJ, Pollack GM, Brouwer KLR. Mechanism of impaired biliary excretion of acetaminophen glucuronide after acute phenobarbital treatment or phenobarbital pretreatment. Drug Metab Dispos 2002; 30: 962969.
  • 15
    Slitt AL, Cherrington NJ, Maher JM, Klaassen CD. Induction of multidrug resistance protein 3 in rat liver is associated with altered vectorial excretion of acetaminophen metabolites. Drug Metab Dispos 2003; 31: 11761186.
  • 16
    Zelcer N, Huisman MT, Reid G, Wielinga P, Breedveld P, Kuil A, et al. Evidence for two interacting ligand binding sites in human multidrug resistance protein 2 (ATP binding cassette C2). J Biol Chem 2003; 278: 2353823544.
  • 17
    Chu XY, Huskey SE, Braun MP, Sarkadi B, Evans DC, Evers R. Transport of ethinylestradiol glucuronide and ethinylestradiol sulfate by the multidrug resistance proteins MRP1, MRP2, and MRP3. J Pharmacol Exp Ther 2004; 309: 156164.
  • 18
    Groen AK, Van Wijland MJ, Frederiks WM, Smit JJ, Schinkel AH, Oude Elferink RP. Regulation of protein secretion into bile: studies in mice with a disrupted mdr2 p-glycoprotein gene. Gastroenterology 1995; 109: 19972006.
  • 19
    Oliveira EJ, Watson GD, Morton NS. A simple microanalytical technique for the determination of paracetamol and its main metabolites in blood spots. J Pharm Biomed Anal 2002; 29: 803809.
  • 20
    Howie D, Adriaenssens PI, Prescott LF. Paracetamol metabolism following overdosage: application of high performance liquid chromatography. J Pharm Pharmacol 1977; 29: 235237.
  • 21
    Tietze F. Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues. Anal Biochem 1969; 27: 502522.
  • 22
    Manautou JE, Hoivik DJ, Tveit A, Emeigh Hart SG, Khairallah EA, Cohen SD. Clofibrate pretreatment diminishes acetaminophen's selective covalent binding and hepatotoxicity. Toxicol Appl Pharmacol 1994; 129: 252263.
  • 23
    Manautou JE, Silva VM, Hennig GE, Whiteley HE. Repeated dosing with the peroxisome proliferator clofibrate decreases the toxicity of model hepatotoxic agents in male mice. Toxicology 1998; 172: 110.
  • 24
    Madhu C, Gregus Z, Klaassen CD. Biliary excretion of acetaminophen-glutathione as an index of toxic activation of acetaminophen: effect of chemicals that alter acetaminophen hepatotoxicity. J Pharmacol Exp Ther 1989; 248: 10691077.
  • 25
    Gonzalez FJ. The study of xenobiotic-metabolizing enzymes and their role in toxicity in vivo using targeted gene disruption. Toxicol Lett 1998; 102–103: 161166.
  • 26
    Brouwer KL, Jones JA. Altered hepatobiliary disposition of acetaminophen metabolites after phenobarbital pretreatment and renal ligation: evidence for impaired biliary excretion and a diffusional barrier. J Pharmacol Exp Ther 1990; 252: 657664.
  • 27
    Soroka CJ, Lee JM, Azzaroli F, Boyer JL. Cellular localization and up-regulation of multidrug resistance-associated protein 3 in hepatocytes and cholangiocytes during obstructive cholestasis in rat liver. HEPATOLOGY 2001; 33: 783791.
  • 28
    Donner MG, Keppler D. Up-regulation of basolateral multidrug resistance protein 3 (Mrp3) in cholestatic rat liver. HEPATOLOGY 2001; 34: 351359.
  • 29
    Day RM, Suzuki Y, Lum JM, White AC, Fanburg BL. Bleomycin upregulates expression of γ-glutamylcysteine synthetase in pulmonary artery endothelial cells. Am J Physiol 2002; 282: L1349L1357.