• 1
    Rousselot LM., Gilbertson FE, Panke WF. Severe hemorrhage from esophagogastric varices: its emergency management with particular reference to portacaval anastomosis. N Engl J Med 1960; 262: 269276.
  • 2
    Sengstaken RW, Blakemore AH. Balloon tamponade for the control of hemorrhage form esophageal varices. Ann Surg 1950; 131: 781789.
  • 3
    Bosch J. Abraldes JG. Management of gastrointestinal bleeding in patients with cirrhosis of the liver. Semin Hematol 2004; 41(1 Suppl. 1 ): 812.
  • 4
    Klupp J, Kohler S, Pascher A, Neuhaus P. Liver transplantation as an ultimate tool to treat portal hypertension. Dig Dis 2005; 23: 6571.
  • 5
    de Franchis R. Evolving consensus in portal hypertension: report of the Baveno IV Consensus Workshop on the methodology of diagnosis and therapy in portal hypertension. J Hepatol 2005; 43: 167176.
  • 6
    Flink H. Yearbook of Health and Medical Care 2002. Accessed October 8, 2005.
  • 7
    D'Amico G, Lucas A. Natural history. Clinical-hemodynamic correlations. Prediction of the risk of bleeding. Baillieres Clin Gastroenterol 1997; 11: 243256.
  • 8
    Graham DY, Lacey Smith J. The course of patients after variceal hemorrhage. Gastroenterology 1981; 80: 800809.
  • 9
    Iouannou G, Doust J, Rockey DC. Terlipressin for acute esophageal variceal hemorrhage, Cochrane Database of Systemic Reviews, Volume 4, 2004.
  • 10
    Wung S, Sung JJ. Update on treatment of variceal hemorrhage. Dig Dis 2002; 20: 134144.
  • 11
    Patch D, Sabin CA, Goulis J, Gerunda G, Greenslade L, Merkel C, et al. A randomized, controlled trial of medical therapy versus endoscopic ligation for the prevention of variceal rebleeding in patients with cirrhosis (comment). Gastroenterology 2002; 123: 10131019.
  • 12
    Carbonell N, Pauwels A, Serfaty L, Fourdan O, Levy VG, Poupon R. Improved survival after variceal bleeding in patients with cirrhosis over the past two decades. HEPATOLOGY 2004; 40: 652659.
  • 13
    McCormick PA, O'Keefe C. Improving prognosis following a first variceal hemorrhage over four decades. Gut 2001; 49: 682685.
  • 14
    El-Serag HB, Everheart JE. Improving prognosis after variceal hemorrhage over an 11-year period in the Department of Veterans Affairs. Am J Gastroenterol 2000; 95: 35663573.
    Direct Link:
  • 15
    Chalasani N, Kahi C, Francois F, Pinto A, Marathe A, Bini EJ, et al. Improved patient survival after acute variceal bleeding: a multicenter cohort study. Am J Gastroenterol 2003; 98: 653659
    Direct Link:
  • 16
    Rosen M. Welcome to the Centre for Epidemiology at the National Board of Health and Welfare December 2004. Available at: Accessed September 3, 2005.
  • 17
    International Classification of diseases Eight Version, WHO, 1966.
  • 18
    International Classification of diseases Ninth Version, WHO, 1987.
  • 19
    International Classification of diseases, Tenth Version, WHO, 1997.
  • 20
    Cox DR. Regression models and life tables. J R Stat Soc B 1972; 34: 187220.
  • 21
    Merkel C, Marin R, Angeli P, Zanella P, Felder M, Bernardinello E, et al. Gruppo Triveneto per l'Ipertensione Portale. A placebo-controlled clinical trial of nadolol in the prophylaxis of growth of small esophageal varices in cirrhosis. Gastroenterology 2004; 127: 476484.
  • 22
    Schepke M, Kleber G, Nurnberg D, Willert J, Koch L, Veltzke-Schlieker W, et al. German Study Group for the Primary Prophylaxis of Variceal Bleeding: ligation versus propanolol for the primary prophylaxis of variceal bleeding in cirrhosis. HEPATOLOGY 2004; 40: 6572.
  • 23
    Averginos A, Armonis A, Manolakopoulos S, Rekoumis G, Argiakis G, Viazis N, et al. Endoscopic sclerotherapy plus propanolol versus propanolol alone in the primary prevention of bleeding in high-risk cirrhotic patients with esophageal varices: a prospective randomized trial. Gastrointest Endosc 2000; 51: 652658.
  • 24
    Imperiale TF, Chalasani N. A meta-analysis of endoscopic variceal ligation for primary prophylaxis of esophageal variceal bleeding. HEPATOLOGY 2001; 33: 802807.
  • 25
    Stokkeland K, Brandt L, Ekbom A, Ösby U, Hultcrantz R. Morbidity and mortality in liver diseases in Sweden 1969–2001 in relation to alcohol consumption. Scand J Gastroenterol. In press.
  • 26
    Odelowo OO, Smoot DT, Kim K. Upper gastrointestinal bleeding in patients with liver cirrhosis. J Natl Med Assoc 2002; 94: 712715.
  • 27
    Barnstorm I, Peterson W: The Swedish Association of Local authorities and Regions (SALAR) 2005,, Accessed September 3, 2005.
  • 28
    Poynard T, Ratziu V, Charlotte F, Goodman Z, McHutchinson J, Albrcht J. Rates and risk factors for fibrosis progression in patients with chronic hepatitis C. J Hepatol 2001; 34: 730739.