Supplementary material for this article can be found on the H EPATOLOGY website ( ).

jws-hep.21180.fig1.ppt293K Supplemental Fig. 1.Example of astrocyte resembling type II astrocytes (arrow) in stratum radiatum of field CA1 after bile duct ligation plus hyperammonemic diet. The brain was immersion fixed in formalin and stained with thionin. Note the swollen, pale appearance of the astrocyte, as well as chromatin dispersion and peripheral location of the nucleolus. The scale bar equals 10 μm.
jws-hep.21180.fig2.ppt243K Supplemental Fig. 2.Histograms showing the density of GFAP immunoreactive astrocytes both in parietal and frontal cortical areas of control, BDL, HD and BDL+HD rats.

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