Liver Biology and Pathobiology
The liver X-receptor alpha controls hepatic expression of the human bile acid–glucuronidating UGT1A3 enzyme in human cells and transgenic mice†
Article first published online: 26 JUL 2006
Copyright © 2006 American Association for the Study of Liver Diseases
Volume 44, Issue 2, pages 368–378, August 2006
How to Cite
Verreault, M., Senekeo-Effenberger, K., Trottier, J., Bonzo, J. A., Bélanger, J., Kaeding, J., Staels, B., Caron, P., Tukey, R. H. and Barbier, O. (2006), The liver X-receptor alpha controls hepatic expression of the human bile acid–glucuronidating UGT1A3 enzyme in human cells and transgenic mice. Hepatology, 44: 368–378. doi: 10.1002/hep.21259
Potential conflict of interest: Nothing to report.
- Issue published online: 26 JUL 2006
- Article first published online: 26 JUL 2006
- Manuscript Accepted: 8 MAY 2006
- Manuscript Received: 20 JAN 2006
- CIHR. Grant Number: MOP 118446
- USPHS. Grant Number: GM49135
- faculty of pharmacy, Laval university (FER)
- Health Research Foundation of Rx&D-CIHR
Supplementary material for this article can be found on the H EPATOLOGY website ( http://interscience.wiley.com/jpages/0270-9139/suppmat/index.html ).
|jws-hep.21259.doc||146K||Suppl Fig. LXRa activates the A3LXRE response element, but fails to activate the DR4 sequence at position -6930 bp of the UGT1A3 promoter.|
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