fax: 416-340-5019
Liver Failure and Disease
You have full text access to this OnlineOpen article
The effect of single oral low-dose losartan on posture-related sodium handling in post-TIPS ascites-free cirrhosis†
Article first published online: 29 AUG 2006
DOI: 10.1002/hep.21309
Copyright © 2006 American Association for the Study of Liver Diseases
Additional Information
How to Cite
Therapondos, G., Hol, L., Benjaminov, F. and Wong, F. (2006), The effect of single oral low-dose losartan on posture-related sodium handling in post-TIPS ascites-free cirrhosis. Hepatology, 44: 640–649. doi: 10.1002/hep.21309
- †
Potential conflict of interest: Nothing to report.
- ‡
fax: 416-340-5019
Publication History
- Issue published online: 29 AUG 2006
- Article first published online: 29 AUG 2006
- Manuscript Accepted: 19 JUN 2006
- Manuscript Received: 25 AUG 2005
References
- 1, , , , , , et al. The management of ascites in cirrhosis: report on the consensus conference of the International Ascites Club. HEPATOLOGY 2003; 38: 258–266.
- 2, , . The controversy over the pathophysiology of ascites formation in cirrhosis. J Gastroenterol Hepatol 1997; 12: 437–444.
- 3, , , , , , et al. Is sinusoidal portal hypertension a necessary factor for the development of hepatic ascites? J Hepatol 1992; 16: 249–250.
- 4, , , , , , et al. Transjugular intrahepatic portosystemic shunting versus paracentesis plus albumin for refractory ascites in cirrhosis. Gastroenterology 2002; 123: 1839–1847.
- 5, , , , , , et al. Transjugular intrahepatic portosystemic shunts: comparison with paracentesis in patients with cirrhosis and refractory ascites: a randomized trial. French Group of Clinicians and a Group of Biologists. J Hepatol 1996; 12: 437–444.
- 6, , , , , , et al. A comparison of paracentesis and transjugular intrahepatic portosystemic shunting in patients with ascites. N Engl J Med 2000; 342: 1701–1707.
- 7, , , , , , et al. The North American study for the treatment of refractory ascites. Gastroenterology 2003; 124: 634–641.
- 8, , , , , , et al. Randomized controlled study of TIPS versus paracentesis plus albumin in cirrhosis with severe ascites. HEPATOLOGY 2004; 40: 629–635.
- 9, , , . Long-term renal sodium handling in patients with cirrhosis treated with transjugular intrahepatic portosystemic shunts for refractory ascites. Am J Med 1999; 106: 315–322.
- 10, , , , , . Peripheral arterial vasodilation hypothesis: a proposal for the initiation of renal sodium and water retention in cirrhosis. HEPATOLOGY 1988; 8: 1151–1157.
- 11, , , , , . The response of atrial natriuretic factor and sodium excretion to dietary sodium challenges in patients with chronic liver disease. HEPATOLOGY 1990; 12: 460–466.
- 12, , , . Pattern of sodium handling and its consequences in patients with preascitic cirrhosis. Gastroenterology 1995; 108: 1820–1827.
- 13, , , , . Central blood volume in cirrhosis: measurement with radionuclide angiography. HEPATOLOGY 1994; 19: 312–321.
- 14, , , . The effect of posture on central blood volume in patients with preascitic cirrhosis on a sodium-restricted diet. HEPATOLOGY 1996; 23: 1141–1147.
- 15, , , , , , et al. Renal sodium retention during upright posture in preascitic cirrhosis. Gastroenterology 1993; 105: 188–193.
- 16, , , , , , et al. Hyperdynamic circulation of advanced cirrhosis: a re-appraisal based on posture-induced changes in hemodynamics. J Hepatol 1995; 22: 309–318.
- 17, , . The mechanism of improved sodium homeostasis of low-dose losartan in preascitic cirrhosis. Hepatology 2002; 35: 1449–1458.
- 18, , , , . Haemodynamic, renal sodium handling, and neurohormonal effects of acute administration of low dose losartan, an angiotensin II receptor antagonist, in preascitic cirrhosis. Gut 2000; 46: 114–120.
- 19, , , , , . Transjugular intrahepatic portosystemic stent shunt: effects on hemodynamics and sodium homeostasis in cirrhosis and refractory ascites. Ann Intern Med 1995; 122: 816–822.
- 20, , . Evaluation of lithium clearance as a marker of proximal tubule sodium handling. Kidney Int 1989; 36: 2–12.
- 21. A rapid method for the determination of para-aminohippuric acid in kidney function tests. J Lab Clin Med 1951; 37: 955–958.
- 22, , . The renal clearance of alkali-stable inulin. J Clin Invest 1955; 34: 1520–1523.
- 23, , , , , , et al. Impaired cardiopulmonary response to exercise in moderate hypertension. Can J Cardiol 1992; 8: 363–371.
- 24, . Determination of catecholamines in rat heart tissue and plasma samples by liquid chromatography with electrochemical detection. J Chromatogr 1982; 228: 143–154.
- 25, , . The renal sympathetic and renin-angiotensin response to lower body negative pressure in well-compensated cirrhosis. Gastroenterology 1998; 115: 397–405.
- 26, , . The onset of sodium retention in experimental cirrhosis in rats is related to a critical threshold of liver function. HEPATOLOGY 1990; 11: 779–786.
- 27, , , , . Urinary sodium balance in patients with cirrhosis: relationship to quantitative parameters of liver function. HEPATOLOGY 1997; 26: 1149–1155.
- 28, , . Renal physiology. In: JohnsonRJ, FeehallyJ, eds. Comprehensive Clinical Nephrology. 2nd edition. Edinburgh: Mosby, 2003: 13–26.
- 29, , Endogenous angiotensin concentrations in specific intrarenal fluid compartments of the rat. J Clin Invest 1990; 86: 1352–1357.
- 30, . Hormonal interactions with the proximal Na(+)-H+ exchanger. Am J Physiol 1990; 258(3 Pt 2): F514–F521.
- 31, , , , , . Mechanisms of angiotensin II natriuresis and antinatriuresis. Am J Physiol 1985; 249(2 Pt 2): F299–F307.
- 32. Neural control of the kidney: functionally specific renal sympathetic nerve fibers. Am J Physiol 2000; 279: R1517–R1524.
- 33. Regulation by adrenal corticosteroids of sodium and potassium transport in loop of Henle and distal tubule of rat kidney. J Clin Invest 1986; 78: 1612–1620.
- 34, , , , , . Vasopressin increases Na-K-2Cl cotransporter expression in thick ascending limb of Henle's loop. Am J Physiol 1999; 276: F96–F103.
- 35. Effect of luminal atrial natriuretic peptide on chloride reabsorption in mouse cortical thick ascending limb: inhibition by endothelin. J Am Soc Nephrol 2000; 11: 1791–1797.
- 36, . Luminal and basolateral endothelin inhibit chloride reabsorption in the mouse thick ascending limb via a Ca2+-independent pathway. J Physiol 1997; 505: 749–758.Direct Link:

1527-3350/asset/olbannerleft.gif?v=1&s=4b2409f9534ed500d3c8da1940a23842e2b9932d)
1527-3350/asset/olbannerright.gif?v=1&s=141b9a8485298533c3e2016e937b0404f7d933e1)
1527-3350/asset/cover.gif?v=1&s=3cd983af6575c8dbfd6b47a63ffa95415ace15f8)