SEARCH

SEARCH BY CITATION

References

  • 1
    Block GD, Locker J, Bowen WC, Petersen BE, Katyal S, Strom SC, et al. Population expansion, clonal growth, and specific differentiation patterns in primary cultures of hepatocytes induced by HGF/SF, EGF and TGF alpha in a chemically defined (HGM) medium. J Cell Biol 1996; 132: 11331149.
  • 2
    Pinkse GGM, Voorhoeve MP, Noteborn M, Terpstra OT, Bruijn JA, De Heer E. Hepatocyte survival depends on beta1-integrin-mediated attachment of hepatocytes to hepatic extracellular matrix. Liver Int 2004; 24: 218226.
  • 3
    Kumaran V, Joseph B, Benten D, Gupta S. Integrin and extracellular matrix interactions regulate engraftment of transplanted hepatocytes in the rat liver. Gastroenterology 2005; 129: 16431653.
  • 4
    Otsu K, Ito K, Kuzumaki T, Iuchi Y. Differential regulation of liver-specific and ubiquitously-expressed genes in primary rat hepatocytes by the extracellular matrix. Cell Phys Biochem 2001; 11: 3340.
  • 5
    Kleinman H, McGarvey ML, Hassell JR, Star VL, Cannon FB, Laurie GW, et al. Basement membrane complexes with biological activity. Biochemistry 1986; 25: 312318.
  • 6
    Kim TH, Bowen WC, Stolz DB, Runge D, Mars WM, Michalopoulos GK. Differential expression and distribution of focal adhesion and cell adhesion molecules in rat hepatocyte differentiation. Exp Cell Res 1998; 244: 93104.
  • 7
    Kim TH, Mars WM, Stolz DB, Petersen BE, Michalopoulos GK. Extracellular matrix remodeling at the early stages of liver regeneration in the rat. HEPATOLOGY 1997; 26: 896904.
  • 8
    Michalopoulos GK, DeFrances MC. Liver regeneration. Science 1997; 276: 6066.
  • 9
    Mohammed F, Khokha R. Thinking outside the cell: proteases regulate hepatocyte division. Trends Cell Biol 2005; 15: 555563.
  • 10
    Hynes RO. Integrins: bidirectional, allosteric signaling machines. Cell 2002; 110: 673687.
  • 11
    Friedrich EB, Liu E, Sinha S, Cook S, Milstone DS, MacRae CA, et al. Integrin-linked kinase regulates endothelial cell survival and vascular development. Mol Cell Biol 2004; 24: 81348144.
  • 12
    Huang Y, Li J, Zhang Y, Wu C. The roles of integrin-linked kinase in the regulation of myogenic differentiation. J Cell Biol 2000; 150: 861872.
  • 13
    Tan C, Cruet-Hennequart S, Troussard A, Fazli L, Costello P, Sutton K, et al. Regulation of tumor angiogenesis by integrin-linked kinase (ILK). Cancer Cell 2004; 5: 7990.
  • 14
    Terpstra L, Prud'homme J, Arabian A, Takeda S, Karsenty G, Dedhar S, St-Arnaud R. Reduced chondrocyte proliferation and chondrodysplasia in mice lacking the integrin-linked kinase in chondrocytes. J Cell Biol 2003; 162: 139148.
  • 15
    Hannigan GE, Leung-Hagesteijn C, Fitz-Gibbon L, Coppolino MG, Radeva G, Filmus J, et al. Regulation of cell adhesion and anchorage-dependent growth by a new beta 1-integrin-linked protein kinase. Nature 1996; 379: 9196.
  • 16
    Radeva G, Petrocelli T, Behrend E, Leung-Hagesteijn C, Filmus J, Slingerland J, et al. Overexpression of the integrin-linked kinase promotes anchorage-independent cell cycle progression. J Biol Chem 1997; 272: 1393713944.
  • 17
    Yoganathan N, Yee A, Zhang Z, Leung D, Yan J, Fazli L, et al. Integrin-linked kinase, a promising cancer therapeutic target: biochemical and biological properties. Pharmacol Ther 2002; 93: 233242.
  • 18
    Persad S, Attwell S, Gray V, Delcommenne M, Troussard A, Sanghera J, et al. Inhibition of integrin-linked kinase (ILK) suppresses activation of protein kinase B/Akt and induces cell cycle arrest and apoptosis of PTEN-mutant prostate cancer cells. Proc Natl Acad Sci U S A 2000; 97: 32073212.
  • 19
    Troussard AA, Mawji NM, Ong C, Mui A, St.-Arnaud R, Dedhar S. Conditional knock-out of integrin-linked kinase demonstrates an essential role in protein kinase B/Akt activation. J Biol Chem 2003; 278: 2237422378.
  • 20
    Wu C, Dedhar S. Integrin linked kinase (ILK) and its interactors: a new paradigm for the coupling of extracellular matrix to actin cytoskeleton and signaling complexes. J Cell Biol 2001; 155: 505510.
  • 21
    Delcommenne M, Tan C, Gray V, Rue L, Woodgett J, Dedhar S. Phosphoinositide-3-OH kinase-dependent regulation of glycogen synthase kinase 3 and protein kinase B/AKT by the integrin-linked kinase. Proc Natl Acad Sci U S A 1998; 95: 1121111216.
  • 22
    Tan C, Costello P, Sanghera J, Dominguez D, Baulida J, de Herreros AG, et al. Inhibition of integrin linked kinase (ILK) suppresses beta-catenin- Lef/Tcf-dependent transcription and expression of the E-cadherin repressor, snail, in APC-/- human colon carcinoma cells. Oncogene 2001; 20: 133140.
  • 23
    Wu C. ILK interactions. J Cell Sci 2001; 114: 25492550.
  • 24
    Wu C. The PINCH-ILK-parvin complexes: assembly, functions and regulation. Biochim Biophys Acta 2004; 1692: 5562.
  • 25
    Li F, Zhang Y, Wu C. Integrin-linked kinase is localized to cell-matrix focal adhesions but not cell-cell adhesion sites and the focal adhesion localization of integrin-linked kinase is regulated by the PINCH-binding ANK repeats. J Cell Sci 1999; 112: 45894599.
  • 26
    Tu Y, Li F, Goicoechea S, Wu C. The LIM-only protein PINCH directly interacts with integrin-linked kinase and is recruited to integrin-rich sites in spreading cells. Mol Cell Biol 1999; 19: 24252434.
  • 27
    Fukuda T, Chen K, Shi X, Wu C. PINCH-1 is an obligate partner of integrin-linked kinase (ILK) functioning in cell shape modulation, motility, and survival. J Biol Chem 2003; 278: 5132451333.
  • 28
    Tu Y, Huang Y, Zhang Y, Hua Y, Wu C. A new focal adhesion protein that interacts with integrin-linked kinase and regulates cell adhesion and spreading. J Cell Biol 2001; 153: 585598.
  • 29
    Zhang Y, Guo L, Chen K, Wu C. A critical role of the PINCH-integrin-linked kinase interaction in the regulation of cell shape change and migration. J Biol Chem 2002; 277: 318326.
  • 30
    Zhang Y, Chen K, Tu Y, Velyvis A, Yang Y, Qin J, et al. Assembly of the PINCH-ILK-CH-ILKBP complex precedes and is essential for localization of each component to cell-matrix adhesion sites. J Cell Sci 2002; 115: 47774786.
  • 31
    Fukuda T, Guo L, Shi X, Wu C. CH-ILKBP regulates cell survival by facilitating the membrane translocation of protein kinase B/Akt. J Cell Biol 2003; 160: 10011008.
  • 32
    Pinkse GGM, Jiawan-Lalai R, Bruijn JA, de Heer E. RGD peptides confer survival to hepatocytes via the beta1-integrin-ILK-pAkt pathway. J Hepatol 2005; 42: 8793.
  • 33
    Su J, Wang LY, Liang YL, Zha XL. Role of cell adhesion signal molecules in hepatocellular carcinoma cell apoptosis. World J Gastroenterol 2005; 11: 46674673.
  • 34
    Tu Y, Wu S, Shi X, Chen K, Wu C. Migfilin and Mig-2 link focal adhesions to filamin and the actin cytoskeleton and function in cell shape modulation. Cell 2003; 113: 3747.
  • 35
    Graham F, Prevec L. Methods in molecular biology. Clifton, NJ: Humana, 1991: pp. 109128.
  • 36
    Kolls J, Peppel K, Silva M, Beutler B. Prolonged and effective blockade of tumor necrosis factor activity through adenovirus-mediated gene transfer. Proc Natl Acad Sci U S A 1994; 91: 215219.
  • 37
    Zhang Y, Guo L, Chen K, Wu C. A critical role of the PINCH-integrin-linked kinase interaction in the regulation of cell shape change and migration. J Biol Chem 2002; 277: 318326.
  • 38
    Mackinnon AC, Qadota H, Norman KR, Moerman DG, Williams BD. C. elegans PAT-4/ILK Functions as an Adaptor Protein within Integrin Adhesion Complexes. Curr Biol 2002; 12: 787797.
  • 39
    Herrmann J, Abriss B, van de Leur E, Weiskirchen S, Gressner AM, Weskirchen R. Comparative analysis of adenoviral transgene delivery via tail vein or portal vein into rat liver. Arch Virol 2004; 149: 16111617.
  • 40
    Michalopoulos GK, Bowen WC, Zajac VF, Beer-Stolz D, Watkins S, Kostrubsky V, et al. Morphogenetic events in mixed cultures of rat hepatocytes and nonparenchymal cells maintained in biological matrices in the presence of hepatocyte growth factor and epidermal growth factor. HEPATOLOGY 1999; 29: 90100.
  • 41
    Ohashi K, Kay MA. Extracellular matrix component cotransplantation prolongs survival of heterotopically transplanted human hepatocytes in mice. Trans Proc 2004; 36: 24692470.
  • 42
    Clark KA, McGrail M, Beckerle MC. Analysis of PINCH function in Drosophila demonstrates its requirement in integrin-dependent cellular processes. Development 2003; 130: 26112621.
  • 43
    Legate KR, Montanez E, Kudlacek O, Fassler R. ILK, PINCH and parvin: the tIPP of integrin signalling. Nat Rev Mol Cell Biol 2006; 7: 2031.
  • 44
    Hannigan G, Troussard A, Dedhar S. Integrin-linked kinase: a cancer therapeutic target unique among its ILK. Nat Rev Cancer 2005; 5: 5163.
  • 45
    Wu C. PINCH, N(i)ck and the ILK: network wiring at cell-matrix adhesions. Trends Cell Biol 2005; 15: 460466.
  • 46
    Persad S, Attwell S, Gray V, Mawji N, Deng JT, Leung D, et al. Regulation of protein kinase B/ Akt-serine-473 phosphorylation by integrin linked kinase (ILK): critical roles for kinase activity and amino acids arginine-211 and serine-343. J Biol Chem 2001; 19: 19.
  • 47
    Sakai T, Li S, Docheva D, Grashoff C, Sakai K, Kostka G, et al. Integrin-linked kinase (ILK) is required for polarizing the epiblast, cell adhesion, and controlling actin accumulation. Genes Dev 2003; 17: 926940.
  • 48
    Wang Y, Krushel LA, Edelman GM. Targeted DNA recombination in vivo using an adenovirus carrying the cre recombinase gene. Proc Natl Acad Sci U S A 1996; 93: 39323936.
  • 49
    Shayakhmetov D, Li ZY, Ni S, Lieber A. Analysis of adenovirus sequestration in the liver, transduction of hepatic cells, and innate toxicity after injection of fiber-modified vectors. J Virol 2004; 78: 53685381.
  • 50
    Shafiei M, Rockey DC. The role of integrin linked kinase in liver wound healing. J Biol Chem 2006; 281: 2486324872.