Supplementary material for this article can be found on the H EPATOLOGY Web site ( ).

jws-hep.21560.pdf154KSupplementary Fig. 1: Representative photographs of the livers in the rats with multifocal liver tumors treated with adenoviruses. Animals bearing multifocal liver tumors were treated as described in the legend to Fig. 1C. Liver pictures were taken from animals treated with Ad/GFP (A), Ad/GM-CSF (B), Ad/IL-12 (C), or Ad/combined (D). Arrows indicate the presence of tumors. Significantly fewer pr smaller tumor nodules were observed in the livers of the animals receiving Ad/IL-12 or Ad/combined therapy.

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