Liver Injury and Regeneration

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Diacylglycerol acyltranferase 1 anti-sense oligonucleotides reduce hepatic fibrosis in mice with nonalcoholic steatohepatitis†

  1. Kanji Yamaguchi1,
  2. Liu Yang1,
  3. Shannon McCall2,
  4. Jiawen Huang1,
  5. Xing Xian Yu3,
  6. Sanjay K. Pandey3,
  7. Sanjay Bhanot3,
  8. Brett P. Monia3,
  9. Yin-Xiong Li1,
  10. Anna Mae Diehl1,‡,*

Article first published online: 13 NOV 2007

DOI: 10.1002/hep.21988

Issue

Hepatology

Hepatology

Volume 47, Issue 2, pages 625–635, February 2008

Additional Information

How to Cite

Yamaguchi, K., Yang, L., McCall, S., Huang, J., Yu, X. X., Pandey, S. K., Bhanot, S., Monia, B. P., Li, Y.-X. and Diehl, A. M. (2008), Diacylglycerol acyltranferase 1 anti-sense oligonucleotides reduce hepatic fibrosis in mice with nonalcoholic steatohepatitis. Hepatology, 47: 625–635. doi: 10.1002/hep.21988

Author Information

  1. 1

    Division of Gastroenterology, Duke University Medical Center, Durham, NC

  2. 2

    Department of Pathology, Duke University Medical Center, Durham, NC

  3. 3

    Department of Antisense Drug Discovery, Isis Pharmaceuticals, Inc., Carlsbad, CA

  1. ‡

    fax: 919-684-4183

*Duke University, Division of Gastroenterology, Ste 1073, GSRB #1 595 LaSalle Street, Durham, NC 27710

  1. †

    Potential conflict of interest: Drs. Monia, Bhanot, and Yu own stock in Isis Pharmaceuticals.

Publication History

  1. Issue published online: 26 JAN 2008
  2. Article first published online: 13 NOV 2007
  3. Manuscript Accepted: 13 AUG 2007
  4. Manuscript Received: 8 MAY 2007

Funded by

  • NIH/NIDDK. Grant Number: RO1DK53792

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