Aberrant methylation of multiple tumor suppressor genes in aging liver, chronic hepatitis, and hepatocellular carcinoma†
Article first published online: 26 DEC 2007
Copyright © 2007 American Association for the Study of Liver Diseases
Volume 47, Issue 3, pages 908–918, March 2008
How to Cite
Nishida, N., Nagasaka, T., Nishimura, T., Ikai, I., Boland, C. R. and Goel, A. (2008), Aberrant methylation of multiple tumor suppressor genes in aging liver, chronic hepatitis, and hepatocellular carcinoma. Hepatology, 47: 908–918. doi: 10.1002/hep.22110
Potential conflict of interest: Nothing to report.
- Issue published online: 26 FEB 2008
- Article first published online: 26 DEC 2007
- Manuscript Accepted: 24 OCT 2007
- Manuscript Received: 6 AUG 2007
- National Cancer Institute, National Institutes of Health. Grant Numbers: R01 CA72851, R01 CA98572
- Baylor Research Institute
Supplementary material for this article can be found on the H EPATOLOGY Web site ( http://interscience.wiley.com/jpages/0270-9139/suppmat/index.html ).
|hep22110-SupplTable1.pdf||9K||Supplemental Table 1:Comparison of methylation status between normal liver at age ≥65 yo and those <65 years of age|
|hep22110-SupplTable2.pdf||10K||Supplemental Table 2:Comparison of methylation status between normal liver and HBV-positive non-cancerous liver of HCC patients|
|hep22110-SupplTable3.pdf||11K||Supplemental Table 3:Differences in methylation levels at each locus between HCC and corresponding non-cancerous tissues in Group-A and Group-B HCC|
|hep22110-SupplTable4.pdf||13K||Supplemental table 4:Comparison of methylation status between HBV-related HCC and virus-negative HCC|
|hep22110-SupplementalFig.1.pdf||413K||Suppl Fig 1: Comparison of methylation densities|
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