Liver Injury and Regeneration

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Expansion of liver cancer stem cells during aging in methionine adenosyltransferase 1A–deficient mice†

  1. C. Bart Rountree1,2,3,‡,*,
  2. Shantha Senadheera2,
  3. Jose M. Mato4,
  4. Gay M. Crooks2,
  5. Shelly C. Lu5,§,*

Article first published online: 31 DEC 2007

DOI: 10.1002/hep.22141

Issue

Hepatology

Hepatology

Volume 47, Issue 4, pages 1288–1297, April 2008

Additional Information

How to Cite

Rountree, C. B., Senadheera, S., Mato, J. M., Crooks, G. M. and Lu, S. C. (2008), Expansion of liver cancer stem cells during aging in methionine adenosyltransferase 1A–deficient mice. Hepatology, 47: 1288–1297. doi: 10.1002/hep.22141

Author Information

  1. 1

    Division of Gastroenterology, Children's Hospital, Los Angeles, Los Angeles, CA

  2. 2

    Gene, Immunology, and Stem Cell Program, Children's Hospital, Los Angeles, Los Angeles, CA

  3. 3

    Division of Pediatric Gastroenterology, Penn State Children's Hospital, Hershey, PA

  4. 4

    CIC bioGUNE, CIBERehd, Technology Park of Bizkaia, Bizkaia, Spain

  5. 5

    Division of Gastrointestinal and Liver Diseases, USC Research Center for Liver Diseases, USC-UCLA Research Center for Alcoholic Liver and Pancreatic Diseases, Keck School of Medicine, USC, Los Angeles, CA

  1. ‡

    fax: 717-531-0653

  2. §

    fax: 323-442-3234

*Division of Pediatric Gastroenterology, Penn State Children's Hospital, H0850, 500 University Drive, P.O. Box 850, Hershey, PA 17033-0850

  1. †

    Potential conflict of interest: Nothing to report.

  2. ‡

    fax: 717-531-0653

  3. §

    fax: 323-442-3234

Publication History

  1. Issue published online: 25 MAR 2008
  2. Article first published online: 31 DEC 2007
  3. Manuscript Accepted: 8 NOV 2007
  4. Manuscript Received: 13 AUG 2007

Funded by

  • AGA/AstraZeneca Fellow/Faculty Transition Award
  • NICHD Fellow of the Pediatric Scientist Development Program (NICHD Grant Award). Grant Number: K12-HD00850
  • USC Research Center for Liver Diseases Pilot Feasibility. Grant Number: DK48522
  • NIH. Grant Numbers: grants DK51719, AA12677, AA13847, AT1576
  • Plan Nacional of I+D SAF 2005-00855
  • HEPADIP-EULSHM-CT-205

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