fax: +33(0)5 55 05 67 67.
Viral Hepatitis
You have full text access to this OnlineOpen article
Ribavirin exposure after the first dose is predictive of sustained virological response in chronic hepatitis C†
Article first published online: 14 JAN 2008
DOI: 10.1002/hep.22217
Copyright © 2008 American Association for the Study of Liver Diseases
Additional Information
How to Cite
Loustaud-Ratti, V., Alain, S., Rousseau, A., Hubert, I. F., Sauvage, F. L., Marquet, P., Denis, F., Lunel, F., Calès, P., Lefebvre, A., Fauchais, A.-L., Liozon, E. and Vidal, E. (2008), Ribavirin exposure after the first dose is predictive of sustained virological response in chronic hepatitis C. Hepatology, 47: 1453–1461. doi: 10.1002/hep.22217
- †
Potential conflict of interest: Nothing to report.
Publication History
- Issue published online: 24 APR 2008
- Article first published online: 14 JAN 2008
- Accepted manuscript online: 14 JAN 2008 12:00AM EST
- Manuscript Accepted: 20 DEC 2007
- Manuscript Received: 11 JUL 2007
Funded by
- Centre Hospitalier Universitaire de Limoges
- Roche, France
- Abstract
- Article
- References
- Cited By
Cited in:
- CrossRef
This article has been cited by:
- 1, , A Pharmacological Profile of Ribavirin and Monitoring of its Plasma Concentration in Chronic Hepatitis C Infection, Journal of Clinical and Experimental Hepatology, 2012, 2, 1, 42
- 2, , , , , , , , , , Critical review of the use of erythropoietin in the treatment of anaemia during therapy for chronic hepatitis C, Journal of Viral Hepatitis, 2012, 19, 2Direct Link:
- 3, , , , , , , , , , , , , , , , Inosine Triphosphatase Polymorphisms and Ribavirin Pharmacokinetics as Determinants of Ribavirin-Associate Anemia in Patients Receiving Standard Anti-HCV Treatment, Therapeutic Drug Monitoring, 2012, 34, 2, 165
- 4, , , , , , , , , , , , , Plasma Ribavirin Trough Concentrations During Treatment of Chronic Hepatitis C in Genotype-1 Patients, Journal of Clinical Gastroenterology, 2012, 46, 4, 328
- 5, , , , , Population Pharmacokinetics and Pharmacodynamics of Ribavirin in Patients with Chronic Hepatitis C Genotype 1 Infection, The AAPS Journal, 2012,
- 6, , Traitements personnalisés du virus de lâhépatite C, La Presse Médicale, 2012, 41, 2, 146
- 7, , , , , , , , , , , , , , , Treatment extension may benefit female genotype 1 chronic hepatitis C patients with complete early virological response to peginterferon-alpha-2b and ribavirin combination therapy, Hepatology Research, 2012, 42, 6Direct Link:
- You have free access to this content8, , , , , , , , , , , , , , , , , Anti-viral therapy in haemodialysed HCV patients: efficacy, tolerance and treatment strategy, Alimentary Pharmacology & Therapeutics, 2011, 34, 4Direct Link:
- 9, , , , , , , , , , Effectiveness of treatment with pegylated interferon and ribavirin in an unselected population of patients with chronic hepatitis C: A Danish nationwide cohort study, BMC Infectious Diseases, 2011, 11, 1, 177
- 10, , , , , , , , , , , , , , , , , , , , , , Influence of HCV genotype 1 subtypes on the virus response to PEG interferon alpha-2a plus ribavirin therapy, Journal of Medical Virology, 2011, 83, 3Direct Link:
- 11, , , , Niveau de preuve du suivi therapeutique pharmacologique de la ribavirine, Thérapie, 2011, 66, 3, 221
- 12, , , , , , , , , , , , Pharmacokinetic and safety profile of raltegravir and ribavirin, when dosed separately and together, in healthy volunteers, Journal of Antimicrobial Chemotherapy, 2011, 66, 6, 1340
- 13, , , , , , , , , , , , , , , Pharmacological exposure to ribavirin: A key player in the complex network of factors implicated in virological response and anaemia in hepatitis C treatment, Digestive and Liver Disease, 2011, 43, 11, 850
- 14, , , , , , , , , , Ribavirin concentration in the later stages of 48 week pegylated interferon-Â 2b plus ribavirin therapy for chronic hepatitis C is useful for predicting virological response, Journal of Antimicrobial Chemotherapy, 2011, 66, 5, 1127
- 15, , , , , , , , , , , Ribavirin plasma concentration is a predictor of sustained virological response in patients treated for chronic hepatitis C virus genotype 2/3 infection, Journal of Viral Hepatitis, 2011, 18, 4Direct Link:
- 16, , , , , , , , Ribavirin Plasma Concentration Measurements in Patients With Hepatitis C: Early Ribavirin Concentrations Predict Steady-State Concentrations, Therapeutic Drug Monitoring, 2011, 33, 1, 40
- 17, , , , , , , , , , , , , Efficacy and tolerability of peginterferon alfa-2a or alfa-2b plus ribavirin in the daily routine treatment of patients with chronic hepatitis C in Germany: The PRACTICE Study, Journal of Viral Hepatitis, 2010, 17, 7Direct Link:
- 18, , , , , , , , , , , , , , , , Hepatitis C Virus Treatment-Related Anemia Is Associated With Higher Sustained Virologic Response Rate, Gastroenterology, 2010, 139, 5, 1602
- 19, , , , , Ribavirin therapeutic drug monitoring: why, when and how?, Fundamental & Clinical Pharmacology, 2010, 24, 4Direct Link:
- 20, , Role of ribavirin in HCV treatment response: now and in the future, Expert Opinion on Pharmacotherapy, 2010, 11, 4, 673
- 21, , , , , , Stability of Ribavirin Concentrations Depending on the Type of Blood Collection Tube and Preanalytical Conditions, Therapeutic Drug Monitoring, 2010, 1
- 22, , , Unraveling the genetic predisposition of ribavirin-induced anaemia, Journal of Hepatology, 2010, 53, 5, 971
- 23, Another ten stories in antiviral drug discovery (part C): “Old” and “new” antivirals, strategies, and perspectives, Medicinal Research Reviews, 2009, 29, 4Direct Link:
- 24, , , , , , Feasibility of Ribavirin Therapeutic Drug Monitoring in Hepatitis C, Therapeutic Drug Monitoring, 2009, 31, 3, 374
- 25, , , , , , , , , Impact of ribavirin plasma level on sustained virological response in patients treated with pegylated interferon and ribavirin for chronic hepatitis C, Alimentary Pharmacology & Therapeutics, 2009, 30, 5Direct Link:
- 26, , , , , , , Optimizing ribavirin dosage: A new challenge to improve treatment efficacy in genotype 1 hepatitis C patients, Gastroentérologie Clinique et Biologique, 2009, 33, 6-7, 580
- 27, , , , , Optimizing the treatment of chronic viral hepatitis C, Expert Review of Gastroenterology & Hepatology, 2009, 3, 6, 607
- 28, , , , , Ribavirin in chronic hepatitis C: past and future, Expert Review of Anti-infective Therapy, 2009, 7, 3, 249
- 29, , , , , , , , , , , Ribavirin Plasma Concentration Predicts Sustained Virological Response to Peginterferon Alfa 2a Plus Ribavirin in Previously Treated HCV-HIV-Coinfected Patients, JAIDS Journal of Acquired Immune Deficiency Syndromes, 2009, 52, 3, 428
- 30
- 31, , , , , Rapid virological response in hepatitis C virus genotype 1 and early ribavirin exposure, Hepatology, 2008, 48, 2Direct Link:
- 32, , , , Rapid virological response to peginterferon and ribavirin for hepatitis C genotype 1: The role of weight-based ribavirin exposure, Hepatology, 2008, 48, 3Direct Link:
- 33, , , , Ribavirin mode of action in chronic hepatitis C: from clinical use back to molecular mechanisms, Liver International, 2008, 28, 10Direct Link:
- 34, , , , Usefulness of monitoring ribavirin plasma concentrations to improve treatment response in patients with chronic hepatitis C, Journal of Antimicrobial Chemotherapy, 2008, 62, 6, 1174

1527-3350/asset/olbannerleft.gif?v=1&s=4b2409f9534ed500d3c8da1940a23842e2b9932d)
1527-3350/asset/olbannerright.gif?v=1&s=141b9a8485298533c3e2016e937b0404f7d933e1)
