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Supplementary material for this article can be found on the H EPATOLOGY Web site ( http://interscience.wiley.com/jpages/0270-9139/suppmat/index.html ).

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hep22252-SupplementaryFigure1.tif8229KSupplementary Fig. 1. Growth curve, cumulative weight gain, and liver weight of female AR +/+ , H-AR /+ and H-AR / mice on HFD. Mice were fed HFD for 8 weeks starting when they were 8 weeks old. (A) Growth curves of animals fed normal chow. (B) Growth curves of animals fed HFD. (C) There were no significant genotype-dependent differences in liver weight between female mice fed normal chow and those fed an HFD.
hep22252-SupplementaryFigure2.tif8228KSupplementary Fig. 2. Fasted glucose level in female AR +/+ , H-AR /+ , and H-AR / mice on an HFD. There were no significant genotype-dependent differences in fasted glucose level in female mice fed normal chow or a HFD.
hep22252-SupplementaryFigure3.tif8228KSupplementary Fig. 3. Expression of Ptp1b and genes involved in lipogenesis determined by QPCR. Hepatic expression of lipogenic genes showed no significant genotype differences in female AR +/+ , H-AR /+ , and H-AR / mice on HFD, but expression of PTP1B was lower in H-AR / mice fed HFD. Data are means ± SEMs of 3 independent experiments (*P < 0.05 AR +/+ (HFD) versus H-AR / (HFD).

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