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References

  • 1
    Tominaga K, Kurata JH, Chen YK, Fujimoto E, Miyagawa S, Abe I, et al. prevalence of fatty liver in Japanese children and relationship to obesity. An epidemiological ultrasonographic survey. Dig Dis Sci 1995; 40: 20022009.
  • 2
    Franzese A, Vajro P, Argenziano A, Puzziello A, Iannucci MP, Saviano MC, et al. Liver involvement in obese children. Ultrasonography and liver enzymes levels at diagnosis and during follow-up in an Italian population. Dig Dis Sci 1997; 42: 14281432.
  • 3
    Schwimmer JB, Deutsch R, Kahen T, Lavine JE, Stanley C, Behling C. Prevalence of fatty liver in children and adolescents. Pediatrics 2006; 118: 13881393.
  • 4
    Chan DF, Li AM, Chu WC, Lavine JE, Stanley C, Behling C. Hepatic steatosis in obese Chinese children. Int J Obes Relat Metab Disord 2004; 28: 12571263.
  • 5
    Kinugasa A, Tsunamoto K, Furukawa N, Sawada T, Kusunoki T, Shimada N. Fatty liver and its fibrous changes found in simple obesity of children. J Pediatr Gatroenterol Nutr 1984; 3: 408414.
  • 6
    Molleston JP, White F, Teckman J, Fitzgerald JF. Obese children with steatohepatitis can develop cirrhosis in childhood. Am J Gastroenterol 2002; 97: 24602462.
    Direct Link:
  • 7
    Adams LA, Feldstein A, Lindor KD, Angulo P. Nonalcoholic fatty liver disease among patients with hypothalamic and pituitary dysfunction. HEPATOLOGY 2004; 39: 909914.
  • 8
    Suzuki D, Hashimoto E, Kaneda K, Tokushige K, Shiratori K. Liver failure caused by non-alcoholic steatohepatitis in an obese young male. J Gastroenterol Hepatol 2005; 20: 327329.
  • 9
    Manton ND, Lipsett J, Moore DJ, Davidson GP, Bourne AJ, Couper RT. Non-alcoholic steatohepatitis in children and adolescents. Med J Aust 2000; 173: 476479.
  • 10
    Vajro P, Fontanella A, Perna C, et al. Persistent hyperaminotransferasemia resolving after weight reduction in obese children. J Pediatr 1994; 125: 239241.
  • 11
    Koçak N, Yüce A, Gürakan F, Ozen H. Obesity: a cause of steatohepatitis in children. Am J Gastroenterol 2000; 95: 10991100.
  • 12
    Lavine JE. Vitamin E treatment of nonalcoholic steatohepatitis in children: a pilot study. J Pediatr 2000; 136: 734738.
  • 13
    Vajro P, Mandato C, Franzese A, Ciccimarra E, Lucariello S, Savoia M, et al. Vitamin E treatment in pediatric obesity-related liver disease: a randomized study. J Pediatr Gastroenterol Nutr 2004; 38: 4855.
  • 14
    Schwimmer JB, Middleton MS, Deutsch R, Lavine JE. A phase 2 clinical trial of metformin as a treatment for non-diabetic paediatric non-alcoholic steatohepatitis. Aliment Pharmacol Ther 2005; 21: 871879.
  • 15
    Nobili V, Manco M, Devito R, Ciampalini P, Piemonte F, Marcellini M. Effect of vitamin E on aminotransferase levels and insulin resistance in children with non-alcoholic fatty liver disease. Aliment Pharmacol Ther 2006; 24: 15531561.
  • 16
    Day CP. From fat to inflammation. Gastroenterology 2006; 130: 207210.
  • 17
    Paolisso G, Giugliano D. Oxidative stress and insulin action: is there a relationship? Diabetologia 1996; 39: 357363
  • 18
    Hill DB, Devalarajan R, Joshi-Barve S, Barve S, McClain CJ. Antioxidants attenuate nuclear factor-Kappa B activation and tumor necrosis factor-alpha production in alcohol hepatitis patient monocytes and rat kupffer cells, in vitro. Clin Biochem 1999; 32: 563570.
  • 19
    Lee KS, Buck M, Houglum K, Chojikier M. Activation of hepatic stellate cells by TGFα and collagen type I is mediated by oxidative stress through c-myb expression, J Clin Invest 1995; 96: 24612468.
  • 20
    Phung N, Farrel G, Robertson G. Vitamin E but not glutathione precursors inhibits hepatic fibrosis in experimental NASH exhibiting oxidative stress and mitochondrial abnormalities. HEPATOLOGY 2001; 34: 361A [Abstract].
  • 21
    Parola M, Muraca R, Dianzani I, Barrera G, Leonarduzzi G, Bendinelli P, et al. Vitamin E dietary supplementation inhibits transforming growth factor beta 1 gene expression in the rat liver. FEBS Lett 1992; 308: 267270.
  • 22
    Strauss RS Comparison of serum concentrations of alpha-tocopherol and beta-carotene in a cross-sectional sample of obese and nonobese children (NHANES III). National Health and Nutrition Examination Survey. J Pediatr 1999; 134: 160165.
  • 23
    Chan AC. Partners in defense, vitamin E and vitamin C. Can J Physiol Pharmacol 1993; 1: 2531.
  • 24
    Suzuki A, Lymp J, Sauver JS, Angulo P, Lindor K. Values and limitations of serum aminotransferases in clinical trials of nonalcoholic steatohepatitis. Liver Int 2006; 26: 12091216.
  • 25
    Cole TJ, Bellizzi MC, Flegal KM, Dietz WH. Establishing a standard definition for child overweight and obesity worldwide: international survey. BMJ 2000; 320: 16.
  • 26
    Centers for Disease Control. BMI Body Mass Index. About BMI for Children and Teens. Available at: http://www.cdc.gov/nccdphp/dnpa/bmi/childrens_BMI/about_childrens_BMI.htm. Accessed March 10, 2008.
  • 27
    The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Follow-up report on the diagnosis of diabetes mellitus. Diabetes Care 2003; 26: 31603167.
  • 28
    Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985; 28: 412419.
  • 29
    Matsuda M, De Fronzo RA. Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp. Diabetes Care 1999; 22: 14621470.
  • 30
    Nobili V, Manco M, Raponi M, Marcellini M. Case management applied to a multispecialist pediatric outpatients clinic for patients affected by nonalcholic fatty liver disease (NAFLD). J Paediatr Child Health 2007; 43: 427430.
  • 31
    Nobili V, Marcellini M, Devito R, Ciampalini P, Piemonte F, Comparcola D, et al. Nonalcoholic fatty liver disease in children: a prospective clinical-pathological study and effect of lifestyle advice. HEPATOLOGY 2006; 44: 458465.
  • 32
    Kleiner DE, Brunt EM, Van Natta M, Behling C, Contos MJ, Cummings OW, et al. Design and validation of a histological scoring system for nonalcoholic fatty liver disease. HEPATOLOGY 2005; 41: 13131321.
  • 33
    Harrison SA, Torgerson S, Hayashi P, Ward J, Schenker S. Vitamin E and vitamin C treatment improves fibrosis in patients with non-alcoholic steatohepatitis. Am J Gastroenterol 2003; 98: 24852490.
    Direct Link:
  • 34
    Adams LA, Angulo P. Vitamins E and C for the treatment of NASH: duplication of results but lack of demonstration of efficacy. Am J Gastroenterol 2003; 98: 23482350.
  • 35
    Bugianesi E, Gentilcore E, Manini R, Natale S, Vanni E, Villanova N, et al. A randomized controlled trial of metformin versus vitamin E or prescriptive diet in nonalcoholic fatty liver disease. Am J Gastroenterol 2005; 100: 10821090.
    Direct Link:
  • 36
    Guallar E, Hanley DF, Miller ER, 3rd. An editorial update: annus horribilis for vitamin E. Ann Intern Med 2005; 143: 143145.
  • 37
    Bjelakovic G, Kikolova D, Gludd LL, Simonetti RG, Gluud C. Mortality in randomized trials of antioxidant supplements for primary and secondary prevention. Systematic review and meta-analysis. JAMA 2007; 29: 842857.
  • 38
    Wilfrey D, Stein R, Saelens BE, Mockus D, Hayden-Wade H, Welch RR, et al. Efficacy of maintenance treatment approaches for childhood overweight. A randomized controlled trial. JAMA 2007; 298: 16611673.