These authors contributed equally to this work.
Histological changes in HCV antibody–positive, HCV RNA–negative subjects suggest persistent virus infection†
Article first published online: 19 JUN 2008
Copyright © 2008 American Association for the Study of Liver Diseases
Volume 48, Issue 6, pages 1737–1745, December 2008
How to Cite
Hoare, M., Gelson, W. T. H., Rushbrook, S. M., Curran, M. D., Woodall, T., Coleman, N., Davies, S. E. and Alexander, G. J. M. (2008), Histological changes in HCV antibody–positive, HCV RNA–negative subjects suggest persistent virus infection. Hepatology, 48: 1737–1745. doi: 10.1002/hep.22484
Potential conflict of interest: As a transplant centre, we state explicitly that no donor organs are or have been obtained from executed prisoners or other institutionalized persons.
- Issue published online: 24 NOV 2008
- Article first published online: 19 JUN 2008
- Accepted manuscript online: 19 JUN 2008 12:00AM EST
- Manuscript Accepted: 9 JUN 2008
- Manuscript Received: 30 APR 2008
- Clinical research training fellowship from the Wellcome Trust
- British Transplantation Society
Additional Supporting Information may be found in the online version of this article.
|HEP_22484_sm_SupplementaryFigure1.tif||4128K||CD4 expression in liver. (A): a subject with viraemia and (B): a non-viraemic subject. There is strong sinusoidal lining cell CD4 expression in the viraemic patient. There is strong lymphocytic expression in the portal tracts in both the viraemic and non-viraemic patients. Scale bars (100μm).|
|HEP_22484_sm_SupplementaryFigure2.tif||66K||Proliferative activity of the inflammatory infiltrate by MCM-2 expression. (A): Mcm-2 expression within portal tracts and (B): Mcm-2 expression within hepatic lobules in non-viraemic subjects (n = 12), viraemic HCV (n = 13) and healthy controls (n = 18). Results were analysed with Kruskal-Wallis test with Dunn's multiple comparison test.|
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