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In the article titled “Hepatitis C Virus JFH-1 Strain Infection in Chimpanzees Is Associated with Low Pathogenicity and Emergence of an Adaptive Mutation” (HEPATOLOGY 2008;48:732-740; DOI: 10.1002/hep.22422), there is an error in the labeling of Fig. 4B. The units for the label “HCV core Ag in medium” should be fmol/mL instead of copies/mL. There is also an error in Table 2, where “Specific Intracellular Infectivity” and “Infectious Virus Secretion” were presented incorrectly. The revised table is shown below and does not change the conclusion of the results.

Table 2. Specific Infectivity and Virus Secretion in Huh7-25 Cells
CloneIntracellular HCV RNA (copies/well)Intracellular Infectivity* (FFU/well)Specific Intracellular Infectivity* (FFU/copies)Extracellular HCV RNA* (copies/well)Extracellular Infectivity* (FFU/well)Specific Extracellular Infectivity (FFU/copies)Infectious Virus Secretion (extra/intra)
  • The data are from day 3 after HCV RNA transfection of the Huh7-25 cells.

  • *

    P < 0.05 comparing JFH-1 WT and G838R.

JFH-1 WT4.40 × 107 ± 1.58 × 1072.27 × 102 ± 5.17 × 1015.45 × 10−6 ± 1.29 × 10−61.83 × 107 ± 1.95 × 1066.17 × 103 ± 9.61 × 1023.37 × 10−4 ± 1.38 × 10−528.8 ± 11.3
JFH-1 G838R2.19 × 107 ± 1.11 × 1069.89 × 102 ± 5.02 × 1014.53 × 10−5 ± 1.38 × 10−65.14 × 107 ± 3.48 × 1062.69 × 104 ± 6.96 × 1035.33 × 10−4 ± 1.83 × 10−427.5 ± 8.3