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References

  • 1
    Repa JJ, Mangelsdorf DJ. The liver X receptor gene team: potential new players in atherosclerosis. Nat Med 2002; 8: 12431248.
  • 2
    Sugden MC, Watts DI, Marshall CE. Regulation of hepatic lipogenesis in starved and diabetic animals by thyroid hormone. Biosci Rep 1981; 1: 757764.
  • 3
    Joseph SB, Laffitte BA, Patel PH, Watson MA, Matsukuma KE, Walczak R, et al. Direct and indirect mechanisms for regulation of fatty acid synthase gene expression by liver X receptors. J Biol Chem 2002; 277: 1101911025.
  • 4
    Laffitte BA, Chao LC, Li J, Walczak R, Hummasti S, Joseph SB, et al. Activation of liver X receptor improves glucose tolerance through coordinate regulation of glucose metabolism in liver and adipose tissue. Proc Natl Acad Sci U S A 2003; 100: 54195424.
  • 5
    Repa JJ, Liang G, Ou J, Bashmakov Y, Lobaccaro JM, Shimomura I, et al. Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta. Genes Dev 2000; 14: 28192830.
  • 6
    Feng X, Jiang Y, Meltzer P, Yen PM. Thyroid hormone regulation of hepatic genes in vivo detected by complementary DNA microarray. Mol Endocrinol 2000; 14: 947955.
  • 7
    Jiang W, Miyamoto T, Kakizawa T, Sakuma T, Nishio S, Takeda T, et al. Expression of thyroid hormone receptor alpha in 3T3–L1 adipocytes; triiodothyronine increases the expression of lipogenic enzyme and triglyceride accumulation. J Endocrinol 2004; 182: 295302.
  • 8
    Willson TM, Kliewer SA. PXR, CAR and drug metabolism. Nat Rev Drug Discov 2002; 1: 259266.
  • 9
    Nakamura K, Moore R, Negishi M, Sueyoshi T. Nuclear pregnane X receptor cross-talk with FoxA2 to mediate drug-induced regulation of lipid metabolism in fasting mouse liver. J Biol Chem 2007; 282: 97689776.
  • 10
    Zhou J, Zhai Y, Mu Y, Gong H, Uppal H, Toma D, et al. A novel pregnane X receptor-mediated and sterol regulatory element-binding protein-independent lipogenic pathway. J Biol Chem 2006; 281: 1501315020.
  • 11
    Pascussi JM, Gerbal-Chaloin S, Duret C, Daujat-Chavanieu M, Vilarem MJ, Maurel P. The tangle of nuclear receptors that controls xenobiotic metabolism and transport: crosstalk and consequences. Annu Rev Pharmacol Toxicol 2007.
  • 12
    Kliewer SA, Goodwin B, Willson TM. The nuclear pregnane X receptor: a key regulator of xenobiotic metabolism. Endocr Rev 2002; 23: 687702.
  • 13
    McGarry JD, Brown NF. The mitochondrial carnitine palmitoyltransferase system: from concept to molecular analysis. Eur J Biochem 1997; 244: 114.
  • 14
    Louet JF, Hayhurst G, Gonzalez FJ, Girard J, Decaux JF. The coactivator PGC-1 is involved in the regulation of the liver carnitine palmitoyltransferase I gene expression by cAMP in combination with HNF4 alpha and cAMP-response element-binding protein (CREB). J Biol Chem 2002; 277: 3799138000.
  • 15
    Bhalla S, Ozalp C, Fang S, Xiang L, Kemper JK. Ligand-activated pregnane X receptor interferes with HNF-4 signaling by targeting a common coactivator PGC-1alpha: functional implications in hepatic cholesterol and glucose metabolism. J Biol Chem 2004; 279: 4513945147.
  • 16
    Li T, Chiang JY. Mechanism of rifampicin and pregnane X receptor inhibition of human cholesterol 7 alpha-hydroxylase gene transcription. Am J Physiol Gastrointest Liver Physiol 2005; 288: G74G84.
  • 17
    LaFave LT, Augustin LB, Mariash CN. S14: insights from knockout mice. Endocrinology 2006; 147: 40444047.
  • 18
    Campbell MC, Anderson GW, Mariash CN. Human spot 14 glucose and thyroid hormone response: characterization and thyroid hormone response element identification. Endocrinology 2003; 144: 52425248.
  • 19
    Oppenheimer JH, Kinlaw WB, Wong NC, Schwartz HL, Mariash CN. Regulation of gene S-14 by triiodothyronine in liver. Horm Metab Res Suppl 1987; 17: 15.
  • 20
    Kinlaw WB, Church JL, Harmon J, Mariash CN. Direct evidence for a role of the “spot 14” protein in the regulation of lipid synthesis. J Biol Chem 1995; 270: 1661516618.
  • 21
    Sanchez-Rodriguez J, Kaninda-Tshilumbu JP, Santos A, Perez-Castillo A. The spot 14 protein inhibits growth and induces differentiation and cell death of human MCF-7 breast cancer cells. Biochem J 2005; 390: 5765.
  • 22
    Zhu Q, Anderson GW, Mucha GT, Parks EJ, Metkowski JK, Mariash CN. The Spot 14 protein is required for de novo lipid synthesis in the lactating mammary gland. Endocrinology 2005; 146: 33433350.
  • 23
    Chou WY, Cheng YS, Ho CL, Liu ST, Liu PY, Kuo CC, et al. Human spot 14 protein interacts physically and functionally with the thyroid receptor. Biochem Biophys Res Commun 2007; 357: 133138.
  • 24
    Roth A, Looser R, Kaufmann M, Blattler SM, Rencurel F, Huang W, et al. Regulatory cross-talk between drug metabolism and lipid homeostasis: constitutive androstane receptor and pregnane X receptor increase Insig-1 expression. Mol Pharmacol 2008; 73: 12821289.
  • 25
    Pichard L, Fabre I, Fabre G, Domergue J, Saint Aubert B, Mourad G, et al. Cyclosporin A drug interactions: screening for inducers and inhibitors of cytochrome P-450 (cyclosporin A oxidase) in primary cultures of human hepatocytes and in liver microsomes. Drug Metab Dispos 1990; 18: 595606.
  • 26
    Pascussi JM, Robert A, Moreau A, Ramos J, Bioulac-Sage P, Navarro F, et al. Differential regulation of constitutive androstane receptor expression by hepatocyte nuclear factor4alpha isoforms. HEPATOLOGY 2007; 45: 11461153.
  • 27
    Drocourt L, Ourlin JC, Pascussi JM, Maurel P, Vilarem MJ. Expression of CYP3A4, CYP2B6, and CYP2C9 is regulated by the vitamin D receptor pathway in primary human hepatocytes. J Biol Chem 2002; 277: 2512525132.
  • 28
    Qin XF, An DS, Chen IS, Baltimore D. Inhibiting HIV-1 infection in human T cells by lentiviral-mediated delivery of small interfering RNA against CCR5. Proc Natl Acad Sci U S A 2003; 100: 183188.
  • 29
    Pascussi JM, Busson-Le Coniat M, Maurel P, Vilarem MJ. Transcriptional analysis of the orphan nuclear receptor constitutive androstane receptor (NR1I3) gene promoter: identification of a distal glucocorticoid response element. Mol Endocrinol 2003; 17: 4255.
  • 30
    Diraison F, Pachiaudi C, Beylot M. Measuring lipogenesis and cholesterol synthesis in humans with deuterated water: use of simple gas chromatographic/mass spectrometric techniques. J Mass Spectrom 1997; 32: 8186.
  • 31
    Folch J, Lees M, Sloane Stanley GH. A simple method for the isolation and purification of total lipides from animal tissues. J Biol Chem 1957; 226: 497509.
  • 32
    Morrison WR, Smith LM. Preparation of fatty acid methyl esters and dimethylacetals from lipids with boron fluoride–methanol. J Lipid Res 1964; 5: 600608.
  • 33
    Guillouzo A, Corlu A, Aninat C, Glaise D, Morel F, Guguen-Guillouzo C. The human hepatoma HepaRG cells: a highly differentiated model for studies of liver metabolism and toxicity of xenobiotics. Chem Biol Interact 2007; 168: 6673.
  • 34
    Mitro N, Vargas L, Romeo R, Koder A, Saez E. T0901317 is a potent PXR ligand: implications for the biology ascribed to LXR. FEBS Lett 2007; 581: 17211726.
  • 35
    Jump DB, Narayan P, Towle H, Oppenheimer JH. Rapid effects of triiodothyronine on hepatic gene expression: hybridization analysis of tissue-specific triiodothyronine regulation of mRNAS14. J Biol Chem 1984; 259: 27892797.
  • 36
    Pawar A, Botolin D, Mangelsdorf DJ, Jump DB. The role of liver X receptor-alpha in the fatty acid regulation of hepatic gene expression. J Biol Chem 2003; 278: 4073640743.
  • 37
    Bramlett KS, Houck KA, Borchert KM, Dowless MS, Kulanthaivel P, Zhang Y, et al. A natural product ligand of the oxysterol receptor, liver X receptor. J Pharmacol Exp Ther 2003; 307: 291296.
  • 38
    Zhou C, Poulton EJ, Grun F, Bammler TK, Blumberg B, Thummel KE, et al. The dietary isothiocyanate sulforaphane is an antagonist of the human steroid and xenobiotic nuclear receptor. Mol Pharmacol 2007; 71: 220229.
  • 39
    Aninat C, Piton A, Glaise D, Le Charpentier T, Langouet S, Morel F, et al. Expression of cytochromes P450, conjugating enzymes and nuclear receptors in human hepatoma HepaRG cells. Drug Metab Dispos 2006; 34: 7583.
  • 40
    Dentin R, Pegorier JP, Benhamed F, Foufelle F, Ferre P, Fauveau V, et al. Hepatic glucokinase is required for the synergistic action of ChREBP and SREBP-1c on glycolytic and lipogenic gene expression. J Biol Chem 2004; 279: 2031420326.
  • 41
    Ishii S, Iizuka K, Miller BC, Uyeda K. Carbohydrate response element binding protein directly promotes lipogenic enzyme gene transcription. Proc Natl Acad Sci U S A 2004; 101: 1559715602.
  • 42
    Zhou J, Febbraio M, Wada T, Zhai Y, Kuruba R, He J, et al. Hepatic fatty acid transporter Cd36 is a common target of LXR, PXR, and PPARgamma in promoting steatosis. Gastroenterology 2008; 134: 556567.
  • 43
    Morere P, Nouvet G, Stain JP, Paillot B, Metayer J, Hemet J. Information obtained by liver biopsy in 100 tuberculous patients [in French]. Sem Hop 1975; 51: 20952102.
  • 44
    Drocourt L, Pascussi JM, Assenat E, Fabre JM, Maurel P, Vilarem MJ. Calcium channel modulators of the dihydropyridine family are human pregnane X receptor activators and inducers of CYP3A, CYP2B, and CYP2C in human hepatocytes. Drug Metab Dispos 2001; 29: 13251331.
  • 45
    Luo G, Cunningham M, Kim S, Burn T, Lin J, Sinz M, et al. CYP3A4 induction by drugs: correlation between a pregnane X receptor reporter gene assay and CYP3A4 expression in human hepatocytes. Drug Metab Dispos 2002; 30: 795804.
  • 46
    Babany G, Uzzan F, Larrey D, Degott C, Bourgeois P, Rene E, et al. Alcoholic-like liver lesions induced by nifedipine. J Hepatol 1989; 9: 252255.
  • 47
    Grieco A, Forgione A, Miele L, Vero V, Greco AV, Gasbarrini A, et al. Fatty liver and drugs. Eur Rev Med Pharmacol Sci 2005; 9: 261263.