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Statins potentiate the in vitro anti-hepatitis C virus activity of selective hepatitis C virus inhibitors and delay or prevent resistance development†
Article first published online: 18 FEB 2009
DOI: 10.1002/hep.22916
Copyright © 2009 American Association for the Study of Liver Diseases
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How to Cite
Delang, L., Paeshuyse, J., Vliegen, I., Leyssen, P., Obeid, S., Durantel, D., Zoulim, F., Op de Beeck, A. and Neyts, J. (2009), Statins potentiate the in vitro anti-hepatitis C virus activity of selective hepatitis C virus inhibitors and delay or prevent resistance development. Hepatology, 50: 6–16. doi: 10.1002/hep.22916
- †
Potential conflict of interest: Nothing to report.
Publication History
- Issue published online: 23 JUN 2009
- Article first published online: 18 FEB 2009
- Accepted manuscript online: 18 FEB 2009 12:00AM EST
- Manuscript Accepted: 11 FEB 2009
- Manuscript Received: 12 SEP 2008
Funded by
- Fonds voor Wetenschappelijk Onderzoek (FWO) Vlaanderen and FWO
- VIRGIL
- European Network of Excellence on Antiviral Drug Resistance (Priority 1 Life Sciences, Genomics and Biotechnology). Grant Number: LSHM-CT-2004-503359
- Fonds National de la Recherche Scientifique. Grant Number: No.3.4.545.06.F
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- 4, , , SKI-1/S1P inhibition: A promising surrogate to statins to block Hepatitis C virus replication, Antiviral Research, 2012,
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- 13, , , , , , , , , , , , , , Open-label, ascending dose, prospective cohort study evaluating the antiviral efficacy of Rosuvastatin therapy in serum and lipid fractions in patients with chronic hepatitis C, Journal of Viral Hepatitis, 2011, 18, 5Direct Link:
- 14, , Statin Therapy Improves Sustained Virologic Response Among Diabetic Patients With Chronic Hepatitis C, Gastroenterology, 2011, 140, 1, 144
- 15, , , The role of insulin resistance in HIV/hepatitis C virus-coinfected patients, Current Opinion in HIV and AIDS, 2011, 6, 6, 553
- 16, , , , , , Triple combinations of neuraminidase inhibitors, statins and fibrates benefit the survival of patients with lethal avian influenza pandemic, Medical Hypotheses, 2011, 77, 6, 1054
- 17, , , , , , , Cholesterol depletion affects infectivity and stability of pseudorabies virus, Virus Research, 2010, 152, 1-2, 180
- 18, , , , , , , , , , , , , , , , Expression profile of lipid metabolism-associated genes in hepatitis C virus-infected human liver, Hepatology Research, 2010, 40, 9Direct Link:
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