These authors contributed equally to this study.
Viral Hepatitis
Sustained virological response to interferon plus ribavirin reduces liver-related complications and mortality in patients coinfected with human immunodeficiency virus and hepatitis C virus†
Article first published online: 2 JUL 2009
DOI: 10.1002/hep.23020
Copyright © 2009 American Association for the Study of Liver Diseases
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How to Cite
Berenguer, J., Álvarez-Pellicer, J., Martín, P. M., López-Aldeguer, J., Von-Wichmann, M. A., Quereda, C., Mallolas, J., Sanz, J., Tural, C., Bellón, J. M., González-García, J. and The GESIDA3603/5607 Study Group (2009), Sustained virological response to interferon plus ribavirin reduces liver-related complications and mortality in patients coinfected with human immunodeficiency virus and hepatitis C virus. Hepatology, 50: 407–413. doi: 10.1002/hep.23020
- †
Potential conflict of interest: Dr. Tural advises Abbott and GlaxoSmithKline. She is on the speakers' bureau of Gilead.
Publication History
- Issue published online: 29 JUL 2009
- Article first published online: 2 JUL 2009
- Manuscript Accepted: 6 APR 2009
- Manuscript Received: 9 NOV 2008
Funded by
- Fundación para la Investigación y la Prevención del SIDA en España (FIPSE). Grant Number: Ref. 36443/03 and 36702/07
- Fondo de Investigación de la Seguridad Social en España (FIS) [Spanish Social Security Foundation for Research]. Grant Numbers: Ref. EC07/90734, Ref RD07/0006/2007
- Red de Investigación en SIDA [AIDS Research Network] (RIS)
- FIS. Grant Number: Ref. PI080928
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- 1, , ¿Podemos adelantar el diagnóstico de la respuesta virológica sostenida a las 12 semanas tras finalizar el tratamiento frente al VHC?, Enfermedades Infecciosas y MicrobiologÃa ClÃnica, 2012, 30, 1, 1
- 2, , , , , , , , , , , , , , , APASL consensus statements and management algorithms for hepatitis C virus infection, Hepatology International, 2012, 6, 2, 409
- 3, , , , , , , Beneficial effect of successful HCV treatment in patients with inherited bleeding disorders, assessed by liver stiffness measurements, Haemophilia, 2012, 18, 3Direct Link:
- 4, , , , , , , , Change in Fibrosis Score as a Predictor of Mortality Among HIV-Infected Patients with Viral Hepatitis, AIDS Patient Care and STDs, 2012, 26, 2, 73
- 5, , , , , Cost-effective Screening for Acute Hepatitis C Virus Infection in HIV-Infected Men Who Have Sex With Men, Clinical Infectious Diseases, 2012,
- 6, , , , , , , , , , , , Effect of Liver Fibrosis on Long-Term Mortality in HIV/Hepatitis C Virus-Coinfected Individuals Who Are Evaluated to Receive Interferon Therapies in the Highly Active Antiretroviral Therapy Era, AIDS Research and Human Retroviruses, 2012, 120420065605003
- 7, , , , , , , , , Factors Associated With Discordance Between Absolute CD4 Cell Count and CD4 Cell Percentage in Patients Coinfected With HIV and Hepatitis C Virus, Clinical Infectious Diseases, 2012, 54, 12, 1798
- 8, , HCV In At Risk Populations: Who Can be Treated and How?, Current Hepatitis Reports, 2012, 11, 1, 1
- 9, , , Impact of erythropoietin on sustained virological response to peginterferon and ribavirin therapy for HCV infection: a systematic review and meta-analysis, Journal of Viral Hepatitis, 2012, 19, 2Direct Link:
- 10, , , , , , , , , , , , , Lack of short-term increase in serum mediators of fibrogenesis and in non-invasive markers of liver fibrosis in HIV/hepatitis C virus-coinfected patients starting maraviroc-based antiretroviral therapy, European Journal of Clinical Microbiology & Infectious Diseases, 2012,
- 11, , Management of Patients Coinfected With HCV and HIV: A Close Look at the Role for Direct-Acting Antivirals, Gastroenterology, 2012, 142, 6, 1324
- 12, , , , , , , , , , , , , , Prediction of response to pegylated interferon plus ribavirin in HIV/hepatitis C virus (HCV)-coinfected patients using HCV genotype, IL28B variations, and HCV-RNA load, Journal of Hepatology, 2012, 56, 4, 788
- 13
- 14, , , , , , , , Acute Hepatitis C Virus in an HIV Clinic: A Screening Strategy, Risk Factors, and Perception of Risk, AIDS Patient Care and STDs, 2011, 25, 10, 571
- 15, , Can We Use the âCâ Word With Confidence? Cure for Chronic Hepatitis C, Gastroenterology, 2011, 140, 3, 766
- 16, , , , , Cross-sectional epidemiology of hepatitis C virus detection and treatment in HIV-infected patients, European Journal of Internal Medicine, 2011, 22, 1, 66
- 17, Current Therapies for Chronic Hepatitis C, Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 2011, 31, 1Direct Link:
- 18, Current treatment for chronic hepatitis C virus/HIV-infected individuals, Current Opinion in HIV and AIDS, 2011, 6, 6, 483
- 19, Direct-acting antivirals for hepatitis C virus infections in patients co-infected with human immunodeficiency virus, Clinics and Research in Hepatology and Gastroenterology, 2011, 35, S75
- 20, Durability of a sustained virologic response in patients with chronic hepatitis C treated with peginterferon and ribavirin, The Korean Journal of Hepatology, 2011, 17, 1, 84
- 21, , , , , , , , , , , , , Durability of a sustained virological response in chronic hepatitis C patients treated with pegylated interferon alfa and ribavirin, The Korean Journal of Hepatology, 2011, 17, 3, 183
- 22, , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Effect of accompanying antiretroviral drugs on virological response to pegylated interferon and ribavirin in patients co-infected with HIV and hepatitis C virus, Journal of Antimicrobial Chemotherapy, 2011, 66, 12, 2843
- 23, , , , , , , , Eligibility and Feasibility of the Treatment of Chronic Hepatitis C in a Cohort of Italian HIV-Positive Patients at a Single HIV Reference Center, AIDS Patient Care and STDs, 2011, 25, 5, 295
- 24
- 25, Hepatic Steatosis in HIV/HCVâCoinfected Patients: Time to Reevaluate!, Gastroenterology, 2011, 140, 3, 772
- 26, , , , Hepatocellular carcinoma in HIV hepatitis C virus, Current Opinion in HIV and AIDS, 2011, 6, 6, 534
- 27, , , , , , , , , Incident Hepatitis C Virus Infection among US HIV-Infected Men Enrolled in Clinical Trials, Clinical Infectious Diseases, 2011, 52, 6, 812
- 28, , , , , Increasing burden of liver disease in patients with HIV infection, The Lancet, 2011, 377, 9772, 1198
- 29, , , , , , , , , , , Insulin resistance predicts re-treatment failure in an efficacy study of peginterferon-α-2a and ribavirin in HIV/HCV co-infected patients, Journal of Hepatology, 2011, 54, 1, 41
- 30, , , , , , , Liver transplantation for patients with human immunodeficiency virus and hepatitis C virus coinfection with special reference to hemophiliac recipients in Japan, Surgery Today, 2011, 41, 10, 1325
- 31, Management of end-stage liver disease in HIV/hepatitis C virus co-infection, Current Opinion in HIV and AIDS, 2011, 6, 6, 527
- 32, , , Peginterferon Alfa-2a Is Superior to Peginterferon Alfa-2b in the Treatment of Naïve Patients with Hepatitis C Virus Infection: Meta-Analysis of Randomized Controlled Trials, Digestive Diseases and Sciences, 2011, 56, 8, 2221
- 33, , Sustained Virologic Response to Antiviral Therapy for Chronic Hepatitis C Virus Infection: A Cure and So Much More, Clinical Infectious Diseases, 2011, 52, 7, 889
- 34, , The HIV/HCV-Coinfected Patient and New Treatment Options, Clinics in Liver Disease, 2011, 15, 3, 585
- 35, , , , , , , , , , , The impact of HIV/HCV co-infection on health care utilization and disability: results of the ACTG Longitudinal Linked Randomized Trials (ALLRT) Cohort, Journal of Viral Hepatitis, 2011, 18, 7Direct Link:
- You have free access to this content36, , , The impact of human immunodeficiency virus on viral hepatitis, Liver International, 2011, 31,Direct Link:
- 37, , , , , , , , , , , The natural history of liver cirrhosis in HIVâhepatitis C virus-coinfected patients, AIDS, 2011, 25, 7, 899
- 38, , , , , , , , Treatment for hepatitis C virus genotype 1 infection in HIV-infected individuals on methadone maintenance therapy, Drug and Alcohol Dependence, 2011, 116, 1-3, 233
- 39, , , , , , , , Treatment of chronic hepatitis C in HIV-infected patients with compensated liver cirrhosis, Journal of Viral Hepatitis, 2011, 18, 8Direct Link:
- 40, , , , , , , , , , , , A Sustained Virologic Response Is Durable in Patients With Chronic Hepatitis C Treated With Peginterferon Alfa-2a and Ribavirin, Gastroenterology, 2010, 139, 5, 1593
- 41, , , , , , , , , , , Care of hepatitis C virus infection in human immunodeficiency virus-infected patients: Modifications in three consecutive large surveys between 2004 and 2009, Journal of Hepatology, 2010, 53, 2, 230
- 42, , , , , , , , , , , , Changes in liver stiffness in patients with chronic hepatitis C with and without HIV co-infection treated with pegylated interferon plus ribavirin, Journal of Antimicrobial Chemotherapy, 2010, 65, 10, 2204
- 43, , , Comparative efficacy and overall safety of different doses of consensus interferon for treatment of chronic HCV infection: a systematic review and meta-analysis, European Journal of Clinical Pharmacology, 2010, 66, 11, 1071
- 44, Evolving challenges in hepatic fibrosis, Nature Reviews Gastroenterology & Hepatology, 2010, 7, 8, 425
- 45, , HIV and HCV Coinfection: Where Are We in 2010?, Current Hepatitis Reports, 2010, 9, 3, 155
- 46, Infección por Virus de Hepatitis C en pacientes coinfectados por el VIH, Revista ClÃnica Española, 2010, 210, 7, 338
- 47, , , , , , , , , , Insulin Resistance Impairs Response to Interferon Plus Ribavirin in Patients Coinfected With HIV and Hepatitis C Virus, JAIDS Journal of Acquired Immune Deficiency Syndromes, 2010, 55, 2, 176
- 48, , , , , , , , , , , Low dose ribavirin for treatment of HCV infected thalassemia major patients: New indications for combination therapy<!â Doctopic: VH â>, Journal of Hepatology, 2010,
- 49, , , , , Manifestations of Chronic Hepatitis C Virus Infection Beyond the Liver, Clinical Gastroenterology and Hepatology, 2010, 8, 12, 1017
- 50, , , , , , , Peginterferon α-2a and ribavirin treatment of patients with haemophilia and hepatitis C virus infection: a single-centre study of 367 cases, Liver International, 2010, 30, 8Direct Link:
- 51, , , , , Prevalence and Challenges of Liver Diseases in Patients With Chronic Hepatitis C Virus Infection, Clinical Gastroenterology and Hepatology, 2010, 8, 11, 924
- 52, , , , , , , , , , Safe co-administration of raltegravir, pegylated-interferon and, ribavirin in HIV individuals with hepatitis C virus-related liver damage, AIDS, 2010, 24, 8, 1231
- 53, , Treating hepatitis C in patients with cirrhosis: The effort is worth it, Journal of Hepatology, 2010, 52, 5, 624
- 54, , , , , Treatment of medical, psychiatric, and substance-use comorbidities in people infected with HIV who use drugs, The Lancet, 2010, 376, 9738, 367
- 55, , , Utilization and Antiviral Therapy in Patients with Chronic Hepatitis C: Analysis of Ambulatory Care Visits in the US, Digestive Diseases and Sciences, 2010, 55, 6, 1744
- 56, , , Hepatobiliary Manifestations of Human Immunodeficiency Virus,Direct Link:
- 57, , HIV and Hepatitis C Co-Infection,Direct Link:

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