Additional supporting information may be found in the online version of this article.

HEP_23134_sm_SuppFig1.tif874KSupporting Figure 1 Panel A, outline map of Thailand to indicate the provinces; panel B, map of Khon Kaen province, North-East Thailand, with box showing the location of the study site villages; panel C, remote sensing image of the region of Khon Kaen where the seven villages addressed in the present study are located. The specific location of the seven study villages in relation to the Chi River, which flows from south west to north east are indicated with the yellow colored stars, as follows: 1, Nongnangkwan; 2, Nongmuang; 3, Loopka; 4, Nongkham; 5, Nongno; 6, Lawa; 7, Chikokor. Panel C modified from Digital Thailand image at
HEP_23134_sm_SuppTabs.doc63KSupporting Table 1. Liver function tests in relationship by case and control status. Supporting Table 2. Median and range concentration in picogram per milliliters of cytokines to Opisthorchis viverrini excretory/secretory products by cases and controls. Supporting Table 3. Median and range of optical density (OD) values, determined by ELISA, for antibody response to Opisthorchis viverrini excretory/secretory products by case and control.

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