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References

  • 1
    Elsharkawy AM, Mann DA. Nuclear factor-κB and the hepatic inflammation-fibrosis-cancer axis. HEPATOLOGY 2007; 46: 590597.
  • 2
    Sun B, Karin M. NF-κB signaling, liver disease and hepatoprotective agents. Oncogene 2008; 27: 62286244.
  • 3
    Hayden MS, West AP, Ghosh S. NF-κB and the immune response. Oncogene 2006; 25: 67586780.
  • 4
    Sakurai T, Maeda S, Chang L, Karin M. Loss of hepatic NF-κB activity enhances chemical hepatocarcingenesis through sustained c-Jun N-terminal kinase 1 activation. Proc Natl Acad Sci U S A 2006; 103: 1054410551.
  • 5
    Luedde T, Beraza N, Kotsikoris V, van Loo G, Nenci A, De Vos R, et al. Deletion of NEMO/IKKγ in liver parenchymal cells causes steatohepatitis and hepatocellular carcinoma. Cancer Cell 2007; 11: 119132.
  • 6
    Pikarsky E, Porat RM, Stein I, Abramovitch R, Amit S, Kasem S, et al. NF-κB functions as a tumour promoter in inflammation-associated cancer. Nature 2004; 431: 462466.
  • 7
    Gerondakis S, Grumont R, Gugasyan R, Wong L, Isomura I, Ho W, et al. Unravelling the complexities of the NF-κB signalling pathway using mouse knockout and transgenic models. Oncogene 2006; 25: 67816799.
  • 8
    Beg AA, Sha WC, Bronson RT, Ghosh S, Baltimore D. Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB. Nature 1995; 376: 167170.
  • 9
    Köntgen F, Grumont RJ, Strasser A, Metcalf D, Li R, Tarlinton D, et al. Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity and interleukin-2 expression. Genes Dev 1995; 9: 19651977.
  • 10
    Weih F, Carrasco D, Durham SK, Barton DS, Rizzo CA, Ryseck RP, et al. Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NF-κB family. Cell 1995; 80: 331340.
  • 11
    Sha WC, Liou HC, Tuomanen EI, Baltimore D. Targeted disruption of the p50 subunit of NF-κB leads to multifocal defects in immune responses. Cell 1995; 80: 321330.
  • 12
    Caamaño JH, Rizzo CA, Durham SK, Barton DS, Raventós-Suárez C, Snapper CM, et al. Nuclear factor (NF)-κB2 (p100/p52) is required for normal splenic microarchitecture and B cell-mediated immune responses. J Exp Med 1998; 187: 185196.
  • 13
    Oakley F, Mann J, Nailard S, Smart DE, Mungalsingh N, Constandinou C, et al. Nuclear factor-κB1 (p50) limits the inflammatory and fibrogenic responses to chronic injury. Am J Pathol 2005; 166: 695708.
  • 14
    Campbell SJ, Anthony DC, Oakley F, Carlsen H, Elsharkawy AM, Blomhoff R, et al. Hepatic nuclear factor κB regulates neutrophil recruitment to the injured brain. J Neuropathol Exp Neurol 2008; 67: 223230.
  • 15
    Carrasco D, Weih F, Bravo R. Developmental expression of the mouse c-rel proto-oncogene in hematopoietic organs. Development 1994; 120: 29913004.
  • 16
    Liou H-C, Hsia CY. Distinctions between c-Rel and other NF-κB proteins in immunity and disease. Bioessays 2003; 25: 767780.
  • 17
    Boffa DJ, Feng B, Sharma V, Dematteo R, Miller G, Suthanthiran M, et al. Selective loss of c-rel compromises dendritic cell activation of T lymphocytes. Cell Immunol 2003; 222: 105115.
  • 18
    Grumont R, Hochrein H, O'Keeffe M, Gugasyan R, White C, Caminschi I, et al. c-Rel regulates interleukin 12 p70 expression in CD*(+) dendritic cells by specifically inducing p5 gene transcription. J Exp Med 2001; 194: 10211032.
  • 19
    Sanjabi S, Hoffmann A, Liou HC, Baltimore D, Smale ST. Selective requirement for c-Rel during IL-12 p40 gene induction in macrophages. Proc Natl Acad Sci U S A 2000; 97: 1270512710.
  • 20
    Belguise K, Sonenshein GE. PKCθ promotes c-Rel-driven mammary tumorigenesis in mice and humans by repressing estrogen receptor α synthesis. J Clin Invest 2007; 117: 40094021.
  • 21
    Liou HC, Jin Z, Tumang J, Andjelic S, Smith KA, Liou ML. c-Rel is crucial for lymphocyte proliferation but dispensible for T cell effector function. Int Immunol 1999; 11: 361371.
  • 22
    Iredale JP. Models of liver fibrosis; exploring the dyamic nature of inflammation and repair in a solid organ. J Clin Invest 2007; 117: 539548.
  • 23
    Liu J, Ma X. Interferon regulator factor 8 regulates RANTES gene transcription in cooperation with interferon regulator factor-1, NF-κB and PU.1. J Biol Chem 2006; 281: 1918819195.
  • 24
    Pan ZZ, Parkyn L, Ray A, Ray P. Inducible lung-specific expression of RANTES: preferential recruitment of neutrophils. Am J Physiol Lung Cell Mol Physiol 2000; 279: L658L666.
  • 25
    Duffield JS, Forbes SJ, Constandinou CM, Clay S, Partolina M, Vuthoori S, et al. Selective depletion of macrophages reveals distinct opposing roles during liver injury and repair. J Clin Invest 2005; 115: 5665.
  • 26
    Maeda S, Kamata H, Luo JL, Leffert H, Karin M. IKKβ couples hepatocyte death to cytokine-driven compensatory proliferation that promotes chemical hepatocarcinogenesis. Cell 2005; 121: 977990.
  • 27
    Fausto N, Campbell JS, Riehle KJ. Liver regeneration. HEPATOLOGY 2006; 43( 2 Suppl. 1): S45S53.
  • 28
    Ye H, Holterman AX, Yoo KW, Franks RR, Costa RH. Premature expression of the winged helix transcription factor HFH-11B in regenerating liver accelerates hepatocyte entry into S phase. Mol Cell Biol 1999; 19: 85708580.
  • 29
    Wang X, Quail E, Hung NJ, Tan Y, Ye H, Costa RH. Increased levels of forkhead box M1B transcription factor in transgenic mouse hepatocytes prevent age-related proliferation defects in regenerating liver. Proc Natl Acad Sci U S A 2001; 98: 1146811473.
  • 30
    Seki E, De Minicis S, Gwak GY, Kluwe J, Inokuchi S, Bursill CA, et al. CCR1 and CCR5 promote hepatic fibrosis in mice. J Clin Invest 2009; 119: 18581870.
  • 31
    Hellerbrand C, Jobin C, Iimuro Y, Licato L, Sartor RB, Brenner DA. Inhibition of NF-κB in activated rat hepatic stellate cells by proteasome inhibitors and an IκB super-repressor. HEPATOLOGY 1998; 27: 12851295.
  • 32
    Oakley F, Meso M, Iredale JP, Green K, Marek CJ, Zhou X, et al. Inhibition of inhibitor of kappaB kinases stimulates hepatic stellate cell apoptosis and recovery from rat liver fibrosis. Gastroenterology 2005; 128: 108120.
  • 33
    Watson MR, Wallace K, Gieling RG, Manas DM, Jaffray E, Hay RT, et al. NF-κB is a critical regulator of the survival of rodent and human hepatic myofibroblasts. J Hepatol 2008; 48: 589597.
  • 34
    Passino MA, Adams RA, Sikorski SL, Akassoglou K. Regulation of hepatic stellate cell differentiation by the neurotrophin receptor p75NTR. Science 2007; 315: 18531856.
  • 35
    Hsia CY, Cheng S, Owyang AM, Dowdy SF, Liou HC. c-Rel regulation of the cell cycle in primary mouse B lymphocytes. Int Immunol 2002; 14: 905916.
  • 36
    Korver W, Schilham MW, Moerer P, van den Hoff MJ, Dam K, Lamers WH, et al. Uncoupling of S phase and mitosis in cardiomyocytes and hepatocytes lacking the winged-helix transcription factor trident. Curr Biol 1998; 8: 13271330.
  • 37
    Laoukili J, Kooistra MR, Brás A, Kauw J, Kerkhoven RM, Morrison A, et al. FoxM1 is required for execution of the mitotic programme and chromosome stability. Nat Cell Biol 2005; 7: 108110.
  • 38
    Krupczak-Hollis K, Wang X, Kalinichenko VV, Gusarova GA, Wang IC, Dennewitz MB, et al. The forkhead box M1 transcription factor is essential for hepatocyte DNA replication and mitosis during mouse liver regeneration. Proc Natl Acad Sci U S A 2002; 99: 1688116886.
  • 39
    Iimuro Y, Nishiura T, Hellerbrand C, Behrns KE, Schoonhoven R, Grisham JW, et al. NF-κB prevents apoptosis and liver dysfunction during liver regeneration. J Clin Invest 1998; 101: 802811.
  • 40
    Chaisson ML, Brooling JT, Ladiges W, Tsai S, Fausto N. Hepatocyte-specific inhibition of NF-κB leads to apoptosis after TNF treatment, but not after partial hepatectomy. J Clin Invest 2002; 110: 193202.
  • 41
    Malato Y, Sander LE, Liedtke C, Al-Masaoudi M, Tacke F, Trautwein C, et al. Hepatocyte-specific inhibitor-of-κB-kinase deletion triggers the innate immune response and promotes earlier cell proliferation during liver regeneration. HEPATOLOGY 2008; 47: 20362050.
  • 42
    Perkins ND. Integrating cell-signalling pathways with NF-κB and IKK function. Nat Rev Mol Cell Biol 2007; 8: 4962.