fax: (81)-3-5803-5829.
Liver Biology/Pathobiology
You have full text access to this OnlineOpen article
Retinoic acid signaling positively regulates liver specification by inducing wnt2bb gene expression in medaka†
Article first published online: 22 OCT 2009
DOI: 10.1002/hep.23387
Copyright © 2009 American Association for the Study of Liver Diseases
Additional Information
How to Cite
Negishi, T., Nagai, Y., Asaoka, Y., Ohno, M., Namae, M., Mitani, H., Sasaki, T., Shimizu, N., Terai, S., Sakaida, I., Kondoh, H., Katada, T., Furutani-Seiki, M. and Nishina, H. (2010), Retinoic acid signaling positively regulates liver specification by inducing wnt2bb gene expression in medaka. Hepatology, 51: 1037–1045. doi: 10.1002/hep.23387
- †
Potential conflict of interest: Nothing to report.
- ‡
fax: (81)-3-5803-5829.
Publication History
- Issue published online: 2 MAR 2010
- Article first published online: 22 OCT 2009
- Accepted manuscript online: 22 OCT 2009 12:00AM EST
- Manuscript Accepted: 9 OCT 2009
- Manuscript Received: 11 AUG 2009
Funded by
- Ministry of Education, Culture, Sport, Science and Technology of Japan
- Ministry of Health, Labor and Welfare of Japan
References
- 1. Hepatocyte differentiation: from the endoderm and beyond. Curr Opin Genet Dev 2001; 11: 568–574.
- 2. Regulatory phases of early liver development: paradigms of organogenesis. Nat Rev Genet 2002; 3: 499–512.
- 3, , , , , , et al. A systematic genome-wide screen for mutations affecting organogenesis in Medaka, Oryzias latipes. Mech Dev 2004; 121: 647–658.
- 4, , , , , , et al. Mutations affecting liver development and function in Medaka, Oryzias latipes, screened by multiple criteria. Mech Dev 2004; 121: 791–802.
- 5, , . Liver development and regeneration: from laboratory study to clinical therapy. Dev Growth Differ 2007; 49: 163–170.
- 6. Stages of normal development in the medaka Oryzias latipes. Mech Dev 2004; 121: 605–618.
- 7, , . Prdm1 acts downstream of a sequential RA, Wnt and Fgf signaling cascade during zebrafish forelimb induction. Development 2006; 133: 2805–2815.
- 8, , , , . The zebrafish neckless mutation reveals a requirement for raldh2 in mesodermal signals that pattern the hindbrain. Development 2001; 128: 3081–3094.
- 9, , , . Differential distribution of retinoic acid synthesis in the chicken embryo as determined by immunolocalization of the retinoic acid synthetic enzyme, RALDH-2. Dev Biol 1999; 210: 288–304.
- 10, , , , , , et al. Retinoic acid signalling in the zebrafish embryo is necessary during pre-segmentation stages to pattern the anterior-posterior axis of the CNS and to induce a pectoral fin bud. Development 2002; 129: 2851–2865.
- 11, , , . Raldh2 expression in optic vesicle generates a retinoic acid signal needed for invagination of retina during optic cup formation. Dev Dyn 2004; 231; 270–277.
- 12, , , , . Restricted expression and retinoic acid-induced downregulation of the retinaldehyde dehydrogenase type 2 (RALDH-2) gene during mouse development. Mech Dev 1997; 62: 67–78.
- 13, , , . Embryonic retinoic acid synthesis is essential for early mouse post-implantation development. Nat Genet 1999; 21: 444–448.
- 14, , . Hoxb-8 has a role in establishing early anterior-posterior polarity in chick forelimb but not hindlimb. Development 1997; 124: 4225–4234.
- 15, , , . Independent roles for retinoic acid in segmentation and neuronal differentiation in the zebrafish hindbrain. Dev Biol 2004; 270: 186–199.
- 16, , , , , , et al. The limb identity gene Tbx5 promotes limb initiation by interacting with Wnt2b and Fgf10. Development 2002; 129: 5161–5170.
- 17, , , . Mesodermal Wnt2b signalling positively regulates liver specification. Nature 2006; 442: 688–691.
- 18, , , , , , et al. Bmp and Fgf signaling are essential for liver specification in zebrafish. Development 2007; 134: 2041–2050.
- 19, , , , , , et al. The hotei mutation of medaka in the anti-Mullerian hormone receptor causes the dysregulation of germ cell and sexual development. Proc Natl Acad Sci U S A 2007; 104: 9691–9696.
- 20, , , , , , et al. Fibin, a novel secreted lateral plate mesoderm signal, is essential for pectoral fin bud initiation in zebrafish. Dev Biol 2007; 303: 527–535.
- 21, , , , , , et al. Genetic analysis of digestive physiology using fluorescent phospholipid reporters. Science 2001; 292: 1385–1388.
- 22, . Retinoic acid signaling is required for a critical early step in zebrafish pancreatic development. Curr Biol 2002; 12: 1215–1220.
- 23, , , . Retinoic acid regulates morphogenesis and patterning of posterior foregut derivatives. Dev Biol 2006; 297: 433–445.
- 24, , , , . Tbx3 controls the fate of hepatic progenitor cells in liver development by suppressing p19ARF expression. Development 2008; 135: 1589–1595.
- 25, , , , , , et al. Fgf10 is essential for limb and lung formation. Nat Genet 1999; 21: 138–141.
- 26, , , , , , et al. Fibroblast growth factor 10 is critical for liver growth during embryogenesis and controls hepatoblast survival via beta-catenin activation. HEPATOLOGY 2007; 46: 1187–1197.
- 27, , , , , , et al. Fgf10 regulates hepatopancreatic ductal system patterning and differentiation. Nat Genet 2007; 39: 397–402.
- 28, . Medaka and zebrafish, an evolutionary twin study. Mech Dev 2004; 121: 629–637.
- 29, . The structure of retinal dehydrogenase type II at 2.7 A resolution: implications for retinal specificity. Biochemistry 1999; 38: 6003–6011.
- 30, , . Hepatocyte migration during liver development requires Prox1. Nature Genet 2000; 25: 254–255.

1527-3350/asset/olbannerleft.gif?v=1&s=4b2409f9534ed500d3c8da1940a23842e2b9932d)
1527-3350/asset/olbannerright.gif?v=1&s=141b9a8485298533c3e2016e937b0404f7d933e1)
