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FilenameFormatSizeDescription
HEP_23516_sm_SupportingFigure1.tif6398KSupporting Figure 1. A. Representative microphotographs of liver specimens from all groups of rats. Hematoxilin and eosin, 100x magnification. B. Effects of cigarette smoking on serum aminotransferases in control and obese rats. Cigarette smoking did not modify ALT serum levels obese rats, while it only induced minor changes in control rats *p<0.01 vs control non-smoker rats. Abbreviations: NS: non-smoker. S: smoker.
HEP_23516_sm_SupportingFigure2.tif6399KSupporting Figure 2. A. Representative microphotographs of liver specimens from all groups of rats. 200x magnification. Fixed liver sections were stained for Sirius Red, as described in Methods. Sirius red staining showed no sign of fibrosis in any of the studied groups. B and C. Hepatic gene expression of procollagen (I)α2 and TIMP-1 from all groups of rats. Acute cigarette exposure did not modify the hepatic expression of fibrogenic genes. Abbreviations: NS: non-smoker. S: smoker. TIMP-1: tissue inhibitor of metalloproteinases 1.
HEP_23516_sm_SupportingFigure3.tif6397KSupporting Figure 3. Representative microphotographs of liver specimens from all groups of rats. 200x magnification. Fixed liver sections were stained for pSMAD2, as described in Methods. Smoking slightly increased the expression of phospho-SMAD2 in hepatocytes in both control and obese rats, especially in those located in pericentral areas. Abbreviations: NS: non-smoker. S: smoker.

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