Hepatobiliary Malignancies

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c-Jun mediates hepatitis C virus hepatocarcinogenesis through signal transducer and activator of transcription 3 and nitric oxide–dependent impairment of oxidative DNA repair†

  1. Keigo Machida1,4,‡,*,
  2. Hidekazu Tsukamoto2,4,5,
  3. Jian-Chang Liu1,
  4. Yuan-Ping Han3,
  5. Sugantha Govindarajan2,4,
  6. Michael M. C. Lai1,7,
  7. Shizuo Akira6,
  8. Jing-hsiung James Ou1

Article first published online: 26 MAR 2010

DOI: 10.1002/hep.23697

Issue

Hepatology

Hepatology

Volume 52, Issue 2, pages 480–492, August 2010

Additional Information

How to Cite

Machida, K., Tsukamoto, H., Liu, J.-C., Han, Y.-P., Govindarajan, S., Lai, M. M. C., Akira, S. and Ou, J.-h. J. (2010), c-Jun mediates hepatitis C virus hepatocarcinogenesis through signal transducer and activator of transcription 3 and nitric oxide–dependent impairment of oxidative DNA repair. Hepatology, 52: 480–492. doi: 10.1002/hep.23697

Author Information

  1. 1

    Molecular Microbiology and Immunology, University of Southern California, Keck School of Medicine, Los Angeles, CA

  2. 2

    Pathology, University of Southern California, Keck School of Medicine, Los Angeles, CA

  3. 3

    Surgery, University of Southern California, Keck School of Medicine, Los Angeles, CA

  4. 4

    Southern California Research Center for Alcoholic Liver and Pancreatic Diseases and Cirrhosis, University of Southern California, Keck School of Medicine, Los Angeles, CA

  5. 5

    Department of Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, CA

  6. 6

    Osaka University, Osaka, Japan

  7. 7

    National Chun Kung University, Tainan, Taiwan

  1. ‡

    fax: 323-442-1721

*Department of Molecular Microbiology and Immunology, University of Southern California, Keck School of Medicine, 211 Zonal Avenue, Los Angeles, CA 90033

  1. †

    Potential conflict of interest: Nothing to report.

  2. ‡

    fax: 323-442-1721

Publication History

  1. Issue published online: 23 JUL 2010
  2. Article first published online: 26 MAR 2010
  3. Manuscript Accepted: 13 MAR 2010
  4. Manuscript Received: 2 OCT 2009

Funded by

  • National Institutes of Health. Grant Numbers: AI40038, 1R01 AA018857-01, P50AA11999
  • Animal Care, Morphology Care, and Pilot Project Program. Grant Number: P01CA123328
  • Zumberge Fellowship, Wright Foundation, American Cancer Society pilot funding
  • Research Center for Liver Diseases. Grant Number: CA108302

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