These authors contributed equally to this study.
Article first published online: 13 DEC 2010
Copyright © 2010 American Association for the Study of Liver Diseases
Volume 53, Issue 1, pages 293–305, January 2011
How to Cite
Wang, Y., Cui, C.-B., Yamauchi, M., Miguez, P., Roach, M., Malavarca, R., Costello, M. J., Cardinale, V., Wauthier, E., Barbier, C., Gerber, D. A., Alvaro, D. and Reid, L. M. (2011), Lineage restriction of human hepatic stem cells to mature fates is made efficient by tissue-specific biomatrix scaffolds. Hepatology, 53: 293–305. doi: 10.1002/hep.24012
Potential conflict of interest: Nothing to report.
Author contributions: Y.W. and C.C.: Conception and design, collection and assembly of data, data analyses and interpretation, article writing; M.Y. and P.M.: collection and/or assembly of data and analyses on collagen chemistry; M.R. and R.M.: collection and assembly of data on cultures on ground biomatrix scaffolds; M.J.C.: data analysis on the TEM and SEM studies; V.C. and D.A.: collection of data onbiomatrix scaffolds of biliary tree tissue (supplement); E.W. and C.B.: isolation of human hepatic stem cells and assistance with cultures; D.G.: help with some of the editing of article; L.M.R.: conception and design, assembly of data, data analyses and interpretation, article writing and editing, final approval of article and financial suppor
Supported by a grant from the North Carolina Biotechnology Center (NCBC), Zenith Biotech (Guilford, CT), Vesta Therapeutics (Bethesda, MD), and from NIH grants (AA014243, IP30-DK065933), NIDDK Grant (DK34987), and an NCI grant (CA016086). A patent application on biomatrix scaffolds has been submitted. V. Cardinale received salary support with a scholarship from Sapienza University of Rome for studies done at UNC. D. Alvaro is supported by MIUR (Italian Minister of University and Research) grants: PRIN #2007, prot. 2007HPT7BA-003.
- Issue published online: 12 JAN 2011
- Article first published online: 13 DEC 2010
- Accepted manuscript online: 24 SEP 2010 10:36AM EST
- Manuscript Accepted: 19 SEP 2010
- Manuscript Received: 28 JUN 2010
- North Carolina Biotechnology Center (NCBC)
- Zenith Biotech (Guilford, CT)
- Vesta Therapeutics (Bethesda, MD), and from NIH. Grant Numbers: AA014243, IP30-DK065933
- NIDDK. Grant Number: DK34987
- NCI. Grant Number: CA016086
- MIUR (Italian Minister of University and Research. Grant Numbers: PRIN #2007, prot. 2007HPT7BA-003
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