Additional supporting information may be found in the online version of this article.

HEP_24110_sm_suppinfofig.tif123KSupporting Figure 1. Sum of intensities (SI) and mRNA (as determined by real-time PCR) box plots for claudin-1 and occludin over time. In HCV-infected patients (A,D), there was a significant increase in the levels of claudin-1 and occludin 12 months after LT (p= 0.007 and p= 0.03, respectively). In HCV-negative patients, the levels of both proteins remained unchanged over time (B,E). In contrast, mRNA claudin-1 levels remained unchanged (C); occludin mRNA levels increased overtime; however, the difference was not statistically significant (F).
HEP_24110_sm_suppinfotable.doc27KSupporting Table 1. Quantification of the levels of claudin-1 and occludin over time. The numbers represent the sum of intensities of claudin-1 and occludin at each time point. Values are depicted as median (ranges) in a logarithmic scale. Pre-LT: biopsies obtained at time of graft reperfusion; 3M: 3 months after liver transplantation; 12M: 12 months after liver transplantation.

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