K.A. is financed by PhD-Program Molecular Medicine of the Medical University of Graz. M.R.S. and M.O. are both supported by the European Commission (GENINCA, contract number 202230). M.F. and Z.T. are supported by the GEN-AU program Bioinformatics Integration Network from the Austrian Ministry for Science and Research.
Evolution of genomic instability in diethylnitrosamine-induced hepatocarcinogenesis in mice†
Article first published online: 2 MAR 2011
Copyright © 2010 American Association for the Study of Liver Diseases
Volume 53, Issue 3, pages 895–904, March 2011
How to Cite
Aleksic, K., Lackner, C., Geigl, J. B., Schwarz, M., Auer, M., Ulz, P., Fischer, M., Trajanoski, Z., Otte, M. and Speicher, M. R. (2011), Evolution of genomic instability in diethylnitrosamine-induced hepatocarcinogenesis in mice. Hepatology, 53: 895–904. doi: 10.1002/hep.24133
Potential conflict of interest: Nothing to report.
See Editorial on Page 723.
- Issue published online: 2 MAR 2011
- Article first published online: 2 MAR 2011
- Accepted manuscript online: 17 DEC 2010 02:46PM EST
- Manuscript Accepted: 9 DEC 2010
- Manuscript Received: 16 NOV 2010
Additional Supporting Information may be found in the online version of this article.
|HEP_24133_sm_suppinfofig1.tif||3854K||Supporting Information Figure 1|
|HEP_24133_sm_suppinfofig2.tif||1687K||Supporting Information Figure 2|
|HEP_24133_sm_suppinfofig3.tif||2932K||Supporting Information Figure 3|
|HEP_24133_sm_suppinfofig4.tif||3847K||Supporting Information Figure 4|
|HEP_24133_sm_suppinfofig5.tif||220K||Supporting Information Figure 5|
|HEP_24133_sm_suppinfofig6.tif||2967K||Supporting Information Figure 6|
|HEP_24133_sm_suppinfotable1.doc||117K||Supporting Table 1: Known tumor suppressor genes in the three most frequently deleted regions of chromosome 4.|
|HEP_24133_sm_suppinfotable2.doc||22K||Supporting Table 2 Percentage of tumors with specific mutations observed in all tumors with β-catenin mutations.|
|HEP_24133_sm_suppinfotable3.doc||20K||Supporting Table 3 H-Ras sequencing results|
|HEP_24133_sm_suppinfotable4.doc||25K||Supporting Table 4 Results of immunohistochemical β-catenin- and Ki67-staining in early and late stage liver tumors induced by DEN and PB.|
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