Potential conflict of interest: Nothing to report.
Article first published online: 7 APR 2011
Copyright © 2011 American Association for the Study of Liver Diseases
Volume 53, Issue 4, page 1405, April 2011
How to Cite
Ratziu, V., Caldwell, S. and Neuschwander-Tetri, B. A. (2011), Reply:. Hepatology, 53: 1405. doi: 10.1002/hep.24233
- Issue published online: 7 APR 2011
- Article first published online: 7 APR 2011
- Accepted manuscript online: 11 FEB 2011 09:42AM EST
- Manuscript Accepted: 26 JAN 2011
We acknowledge the pioneering work on the therapeutic value of glitazones in nonalcoholic steatohepatitis by Cusi, Harrison, Schenker, and their coworkers. We thank them for the correction related to the inclusion criteria of Belfort et al.'s study,1 and we apologize to the readers for this error in our article.2 We welcome the additional information on the calculation of the combined necroinflammation score. This information, though clearly relevant, does not appear in the online or print edition of the article, which simply refers to the Kleiner classification with no further detail. Critical details of the methodology or results should not be omitted despite the inevitable space constraints still invoked by journals in the digital era. We look forward to seeing the results of their ongoing studies, and we anticipate that the metabolic studies undertaken by them will continue to shed light on the pathogenesis of nonalcoholic steatohepatitis and potential treatment options.
- 1A placebo-controlled trial of pioglitazone in patients with nonalcoholic steatohepatitis. N Engl J Med 2006; 355: 2297-2307., , , , , , et al.
- 2Therapeutic trials in nonalcoholic steatohepatitis: insulin sensitizers and related methodological issues. HEPATOLOGY 2010; 52: 2206-2215., , .
Vlad Ratziu M.D.*, Stephen Caldwell M.D., Brent A. Neuschwander-Tetri M.D., * Institut National de la Santé et de la Recherche Médicale, Unités Mixtes de Recherche en Santé 893, Hôpital Pitié Salpêtrière, (Assistance Publique Hôpitaux de Paris), Université Pierre et Marie Curie, Paris, France, Division of Gastroenterology and Hepatology, University of Virginia, Charlottesville, VA, Division of Gastroenterology and Hepatology, Saint Louis University, St. Louis, MO.