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Viral Hepatitis
Association of gene expression involving innate immunity and genetic variation in interleukin 28B with antiviral response†‡
Article first published online: 29 NOV 2011
DOI: 10.1002/hep.24623
Copyright © 2011 American Association for the Study of Liver Diseases
Additional Information
How to Cite
Asahina, Y., Tsuchiya, K., Muraoka, M., Tanaka, K., Suzuki, Y., Tamaki, N., Hoshioka, Y., Yasui, Y., Katoh, T., Hosokawa, T., Ueda, K., Nakanishi, H., Itakura, J., Takahashi, Y., Kurosaki, M., Enomoto, N., Nitta, S., Sakamoto, N. and Izumi, N. (2012), Association of gene expression involving innate immunity and genetic variation in interleukin 28B with antiviral response. Hepatology, 55: 20–29. doi: 10.1002/hep.24623
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Potential conflict of interest: Nothing to report.
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Supported by grants from the Japanese Ministry of Education, Culture, Sports, Science and Technology and the Japanese Ministry of Welfare, Health and Labor. The funding source had no role in the collection, analysis, or interpretation of the data, or in the decision to submit the article for publication.
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Publication History
- Issue published online: 21 DEC 2011
- Article first published online: 29 NOV 2011
- Accepted manuscript online: 24 AUG 2011 01:53PM EST
- Manuscript Accepted: 16 AUG 2011
- Manuscript Received: 14 MAY 2011
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This article has been cited by:
- 1, , , , , , , , , , , , , , , , , , , , , , , , A variant upstream of IFNL3 (IL28B) creating a new interferon gene IFNL4 is associated with impaired clearance of hepatitis C virus, Nature Genetics, 2013, 45, 2, 164
- 2, , , , , , , , , Association between hepatic steatosis and hepatic expression of genes involved in innate immunity in patients with chronic hepatitis C, Cytokine, 2013,
- 3, , , , , , , , , , , , , , , , Differential effects of donor and recipient IL28B and DDX58 SNPs on severity of HCV after liver transplantation, Journal of Hepatology, 2013, 58, 5, 969
- 4, , , , , , , , , , , , , , , , Dysregulation of innate immunity in hepatitis C virus genotype 1 IL28B-unfavorable genotype patients: Impaired viral kinetics and therapeutic response, Hepatology, 2012, 56, 2Direct Link:
- 5, , , , Genetics of IL28B and HCV—response to infection and treatment, Nature Reviews Gastroenterology & Hepatology, 2012, 9, 7, 406
- 6, , IL28B Polymorphisms as a Pretreatment Predictor of Response to HCV Treatment, Infectious Disease Clinics of North America, 2012, 26, 4, 863
- You have free access to this content7, , , Impact of interleukin-28B genotype on in vitro and in vivo systems of hepatitis C virus replication, Hepatology Research, 2012, 42, 9Direct Link:
- 8, , , , , , , Response-guided peginterferon-alpha-2b plus ribavirin therapy for chronic hepatitis C patients with genotype 2 and high viral loads, Hepatology Research, 2012, 42, 9Direct Link:

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