Steatohepatitis/Metabolic Liver Disease
Article first published online: 30 JAN 2012
Copyright © 2011 American Association for the Study of Liver Diseases
Volume 55, Issue 3, pages 790–799, March 2012
How to Cite
Jourdan, T., Demizieux, L., Gresti, J., Djaouti, L., Gaba, L., Vergès, B. and Degrace, P. (2012), Antagonism of peripheral hepatic cannabinoid receptor-1 improves liver lipid metabolism in mice: Evidence from cultured explants. Hepatology, 55: 790–799. doi: 10.1002/hep.24733
Potential conflict of interest: Nothing to report.
This work was supported by grants from Sanofi-Aventis and the Région Bourgogne.
- Issue published online: 23 FEB 2012
- Article first published online: 30 JAN 2012
- Accepted manuscript online: 10 OCT 2011 11:04AM EST
- Manuscript Accepted: 26 SEP 2011
- Manuscript Received: 16 DEC 2010
Additional Supporting Information may be found in the online version of this article.
|HEP_24733_sm_SuppFig1.eps||6442K||Supporting Information Figure 1. Competitive effect of SR141716 on AEA inhibition of FA oxidation rates in lean mice. Liver explants were treated for 21 hours with AEA (5 μM) and increasing concentrations of SR141716 (0-500 nM) or only with vehicle (CON). Results are expressed as means ± SEM (n = 5). *P < 0.05, different from CON; †P < 0.05, different from 0 nM of SR141716.|
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