These authors contributed equally to this work.
Autoimmune, Cholestatic and Biliary Disease
Version of Record online: 19 DEC 2011
Copyright © 2011 American Association for the Study of Liver Diseases
Volume 55, Issue 3, pages 833–845, March 2012
How to Cite
Ho, C., Wang, C., Mattu, S., Destefanis, G., Ladu, S., Delogu, S., Armbruster, J., Fan, L., Lee, S. A., Jiang, L., Dombrowski, F., Evert, M., Chen, X. and Calvisi, D. F. (2012), AKT (v-akt murine thymoma viral oncogene homolog 1) and N-Ras (neuroblastoma ras viral oncogene homolog) coactivation in the mouse liver promotes rapid carcinogenesis by way of mTOR (mammalian target of rapamycin complex 1), FOXM1 (forkhead box M1)/SKP2, and c-Myc pathways. Hepatology, 55: 833–845. doi: 10.1002/hep.24736
Potential conflict of interest: Nothing to report.
Supported by NIH grants R21CA131625 and R01CA136606 to XC; P30DK026743 for UCSF Liver Center; the Deutsche Forschungsgemeinschaft DFG (grant number Do622/2-1) to FD and (grant number Ev168/2-1) to ME. SM and GD were supported in part by a fellowship from the Master and Back Program, Sardegna Ricerche, RAS.
- Issue online: 23 FEB 2012
- Version of Record online: 19 DEC 2011
- Accepted manuscript online: 12 OCT 2011 12:50PM EST
- Manuscript Accepted: 29 SEP 2011
- Manuscript Received: 6 JUL 2011
Additional Supporting Information may be found in the online version of this article.
|HEP_24736_sm_SuppFig1.tif||5936K||Supplementary Figure 1.|
|HEP_24736_sm_SuppFig2.tif||16956K||Supplementary Figure 2.|
|HEP_24736_sm_SuppFig3.tif||11223K||Supplementary Figure 3.|
|HEP_24736_sm_SuppFig4.tif||9098K||Supplementary Figure 4.|
|HEP_24736_sm_SuppFig5.tif||925K||Supplementary Figure 5.|
|HEP_24736_sm_SuppFig6.tif||761K||Supplementary Figure 6.|
|HEP_24736_sm_SuppFig7.tif||912K||Supplementary Figure 7.|
|HEP_24736_sm_SuppFig8.tif||837K||Supplementary Figure 8.|
|HEP_24736_sm_SuppFig9.tif||948K||Supplementary Figure 9.|
|HEP_24736_sm_SuppFig10.tif||628K||Supplementary Figure 10.|
|HEP_24736_sm_SuppTab1.doc||44K||Supporting Table 1. List of the primary antibodies used for immunoblotting and immunoprecipitation analysis.|
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