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References

  • 1
    Adams PC, Barton JC. How I treat hemochromatosis. Blood 2010; 116: 317-325.
  • 2
    Adams PC, Reboussin DM, Barton JC, McLaren CE, Eckfeldt JH, McLaren GD, et al. Hemochromatosis and iron-overload screening in a racially diverse population. N Engl J Med 2005; 352: 1769-1778.
  • 3
    McLaren GD, McLaren CE, Adams PC, Barton JC, Reboussin DM, Gordeuk VR, et al. Clinical manifestations of hemochromatosis in HFE homozygotes identified by screening. Can J Gastroenterol 2008; 22: 923-930.
  • 4
    Adams PC, Barton JC, McLaren GD, Acton RT, Speechley M, McLaren CE, et al. Screening for iron overload: lessons from the HEIRS Study. Can J Gastroenterol 2009; 23: 771-774.
  • 5
    Adams PC, Passmore L, Chakrabarti S, Reboussin D, Acton R, Barton J, et al. Liver diseases in the Hemochromatosis and Iron Overload Screening Study. Clin Gastroenterol Hepatol 2006; 4: 918-923.
  • 6
    Beaton M, Adams PC. Assessment of silent liver fibrosis in hemochromatosis C282Y homozygotes with normal transaminase levels. Clin Gastroenterol Hepatol 2008; 6: 713-714.
  • 7
    Lin E, Adams PC. Biochemical liver profile in hemochromatosis. A survey of 100 patients. J Clin Gastroenterol 1991; 13: 316-320.
  • 8
    Powell EE, Ali A, Clouston AD, Dixon JL, Lincoln DJ, Purdie DM, et al. Steatosis is a cofactor in liver injury in hemochromatosis. Gastroenterology 2005; 129: 1937-1943.
  • 9
    Adams PC, Barton JC. A diagnostic approach to hyperferritinemia with a non-elevated transferrin saturation. J Hepatol 2011; 55: 453-458.
  • 10
    Hultcrantz R, Glaumann H, Lindberg G, Nilsson LH. Liver investigation in 149 asymptomatic patients with moderately elevated activities of serum aminotransferases. Scand J Gastroenterol 1986; 21: 109-113.
  • 11
    Friedman LS, Dienstag JL, Watkins E, Hinkle CA, Spiers JA, Rieder SV, et al. Evaluation of blood donors with elevated serum alanine aminotransferase levels. Ann Intern Med 1987; 107: 137-144.
  • 12
    Hay JE, Czaja AJ, Rakela J, Ludwig J. The nature of unexplained chronic aminotransferase elevations of a mild to moderate degree in asymptomatic patients. Hepatology 1989; 9: 193-197.
  • 13
    Daniel S, Ben-Menachem T, Vasudevan G, Ma CK, Blumenkehl M. Prospective evaluation of unexplained chronic liver transaminase abnormalities in asymptomatic and symptomatic patients. Am J Gastroenterol 1999; 94: 3010-3014.
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  • 14
    Bhavnani M, Lloyd D, Bhattacharyya A, Marples J, Elton P, Worwood M. Screening for genetic haemochromatosis in blood samples with raised alanine aminotransferase. Gut 2000; 46: 707-710.
  • 15
    Meyer TJ, Van Kooten D, Prochazka AV. Pursuing mild elevations of liver enzyme values to exclude hemochromatosis. South Med J 1990; 83: 1277-1279.
  • 16
    Adams P, Zaccaro D, Moses G, Eckfeldt J, Leiendecker-Foster C, McLaren C, et al. Comparison of the unsaturated iron binding capacity with transferrin saturation as a screening test to detect C282Y homozygotes for hemochromatosis in 101,168 participants in the HEIRS study. Clin Chem 2005; 51: 1048-1051.
  • 17
    Acton RT, Barton JC, Passmore LV, Adams PC, McLaren GD, Leiendecker-Foster C, et al. Accuracy of family history of hemochromatosis or iron overload: the hemochromatosis and iron overload screening study. Clin Gastroenterol Hepatol 2008; 6: 934-938.
  • 18
    Assy N, Adams PC. Predictive value of family history in diagnosis of hereditary hemochromatosis. Dig Dis Sci 1997; 42: 1312-1315.