Version of Record online: 29 MAY 2012
Copyright © 2012 American Association for the Study of Liver Diseases
Volume 55, Issue 6, pages 1876–1888, June 2012
How to Cite
Komuta, M., Govaere, O., Vandecaveye, V., Akiba, J., Van Steenbergen, W., Verslype, C., Laleman, W., Pirenne, J., Aerts, R., Yano, H., Nevens, F., Topal, B. and Roskams, T. (2012), Histological diversity in cholangiocellular carcinoma reflects the different cholangiocyte phenotypes. Hepatology, 55: 1876–1888. doi: 10.1002/hep.25595
Potential conflict of interest: Nothing to report.
Supported by an Interuniversity Attraction Pole (IUAP) grant from Belspo Belgium.
- Issue online: 29 MAY 2012
- Version of Record online: 29 MAY 2012
- Accepted manuscript online: 23 JAN 2012 06:11AM EST
- Manuscript Accepted: 23 DEC 2011
- Manuscript Received: 30 JUL 2011
- Interuniversity Attraction Pole (IUAP) grant from Belspo Belgium
Additional Supporting Information may be found in the online version of this article.
|HEP_25595_sm_SuppFig1.tif||7676K||Supplementary Figure 1. The different features of stroma in the different subtypes of Cholangiocellular carcinomas (CCs). (A) Hepatocytic differentiation area. (B) Ductular area. (C) Mucin-producing CC area.|
|HEP_25595_sm_SuppFig2.tif||3194K||Supplementary Figure 2. Gene expression profiling. Box-plots of RT-PCR results for hepatic progenitor cell (HPC)/biliary markers (KRT19/7,and EpCAM). Hilar bile duct (BD) (n=6), segmental BD (n=4), and ductular reaction (DR) (n=8).|
|HEP_25595_sm_SuppFig3.tif||3566K||Supplementary Figure 3. Gene expression profiling. Box-plots of RT-PCR results for hepatic progenitor cell (HPC)/biliary markers (KRT7, ANXA3, and TACSTD2). Hilar cholangiocellular carcinomas (Hilar CCs) (n=5), mucin-producing intrahepatic CCs (muc-ICCs) (n=6), ICC with mixed features (mixed-ICCs) (n=7), and cholangiolocellular carcinomas (CLCs) (n=7).|
|HEP_25595_sm_SuppFig4.tif||5642K||Supplementary Figure 4. The overall survival rate in patients with hilar cholangiocellular carcinomas (Hilar CCs), mucin-producing intrahepatic CCs (muc-ICCs), ICCs with mixed features (mixed-ICCs) and cholangiolocellular carcinomas (CLCs). Hilar CC and muc-ICC group tended to show worse prognosis compared with mixed-ICC and CLC group.|
|HEP_25595_sm_SuppTab.doc||36K||Supporting Information Tables|
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