Article first published online: 2 JUL 2012
Copyright © 2012 American Association for the Study of Liver Diseases
Volume 56, Issue 2, pages 532–543, August 2012
How to Cite
D'Ambrosio, R., Aghemo, A., Rumi, M. G., Ronchi, G., Donato, M. F., Paradis, V., Colombo, M. and Bedossa, P. (2012), A morphometric and immunohistochemical study to assess the benefit of a sustained virological response in hepatitis C virus patients with cirrhosis. Hepatology, 56: 532–543. doi: 10.1002/hep.25606
Potential conflict of interest: Alessio Aghemo is on an advisory committee for Roche. Maria Grazia Rumi is on advisory committees for Tibotec, Roche, and Janssen Cilag. Massimo Colombo has received grant and research support from Merck, Roche, BMS, and Gilead Science; is on advisory committees for Merck, Roche, Novartis, Bayer, BMS, Gilead Science, Tibotec, Vertex, and Achillion; and has received speaking and teaching engagements from Tibotec, Roche, Novartis, Bayer, BMS, Gilead Science, and Vertex.
Dr. D'Ambrosio received a research grant from Università degli Studi di Milano (FSE, Regione Lombardia).
- Issue published online: 25 JUL 2012
- Article first published online: 2 JUL 2012
- Accepted manuscript online: 23 JAN 2012 07:02AM EST
- Manuscript Accepted: 7 JAN 2012
- Manuscript Received: 14 OCT 2011
Additional Supporting Information may be found in the online version of this article.
|HEP_25606_sm_SuppFig1.tif||12799K||Supporting Information Figure 1: A-D: lymphocyte immunophenotyping on liver biopsies from the same patient obtained after the achievement of an SVR. (A) B-cells are mainly confined within the lymphoid follicle (CD20 immunostaining, original magnification 200X). (B) CD8+ T-cells are expressed within the lymphoid follicle and the portal tract (CD8 immunostaining, original magnification 200X). (C) CD4+ T-cells are present only in the portal tract, whereas no cells are labeled at the interface (CD4 immunostaining, original magnification 200X). (D) TReg FoxP3+ cells are rare in the portal tract (arrows; FoxPs immunostaining, original magnification 200X).|
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