Version of Record online: 14 OCT 2012
Copyright © 2012 American Association for the Study of Liver Diseases
Volume 56, Issue 5, pages 1602–1610, November 2012
How to Cite
Holz, L. E., Yoon, J. C., Raghuraman, S., Moir, S., Sneller, M. C. and Rehermann, B. (2012), B cell homeostasis in chronic hepatitis C virus–related mixed cryoglobulinemia is maintained through naïve B cell apoptosis. Hepatology, 56: 1602–1610. doi: 10.1002/hep.25821
Potential conflict of interest: Nothing to report.
Supported by the National Institutes of Health intramural research program (National Institute of Diabetes and Digestive and Kidney Diseases and National Institute of Allergy and Infectious Diseases).
- Issue online: 31 OCT 2012
- Version of Record online: 14 OCT 2012
- Accepted manuscript online: 4 MAY 2012 05:39AM EST
- Manuscript Accepted: 28 APR 2012
- Manuscript Received: 12 NOV 2011
Additional Supporting Information may be found in the online version of this article.
|HEP_25821_sm_SuppFig1.tif||4732K||Supporting Information Figure 1: HCV-infected patients with MC display reduced numbers of CD19+ B cells, mature B cells and naïve mature B cells in the peripheral blood. (A-B) White blood cell (WBC) and total lymphocyte count in the blood. (C-F) Number of CD19+ B cells (C), mature B cells (D), naïve mature B cells (E) and activated B cells (F) per microliter blood in HCV-infected patients with and without MC and HBV-infected patients. Data were not available from healthy blood donors because differential blood counts are not performed under the protocol for research blood donations from healthy controls. B cell populations were identified based on markers described in Fig. 1. Results represent mean ± S.E.M. * indicates p<0.05, *** p<0.001.|
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