Version of Record online: 14 OCT 2012
Copyright © 2012 American Association for the Study of Liver Diseases
Volume 56, Issue 5, pages 1622–1630, November 2012
How to Cite
Hulskotte, E., Gupta, S., Xuan, F., van Zutven, M., O'Mara, E., Feng, H.-P., Wagner, J. and Butterton, J. (2012), Pharmacokinetic interaction between the hepatitis C virus protease inhibitor boceprevir and cyclosporine and tacrolimus in healthy volunteers. Hepatology, 56: 1622–1630. doi: 10.1002/hep.25831
Potential conflict of interest: Drs. Xuan, Butterton, and Feng own stock in Merck.
Funded by Merck & Co., Inc.
Presented at the 16th Annual Meeting of HEP DART, December 4-8, 2011, Kauai, Hawaii.
- Issue online: 31 OCT 2012
- Version of Record online: 14 OCT 2012
- Accepted manuscript online: 11 MAY 2012 04:36AM EST
- Manuscript Accepted: 4 MAY 2012
- Manuscript Received: 7 FEB 2012
- 4In vitro assessment of drug-drug interaction potential of boceprevir as an inhibitor and inducer of drug metabolizing enzymes and transporters [Abstract]. HEPATOLOGY 2011; 54( Suppl. 4): 547A., , , , , , et al.
- 6Prograf tacrolimus capsules, tacrolimus injection (for intravenous infusion only) [prescribing information]. Deerfield, IL: Astellas Pharma US, Inc.; 2006.
- 7Neoral soft gelatin capsules (cyclosporine capsules, USP) modified Neoral oral solution (cyclosporine oral solution, USP) modified. East Hanover, NJ: Novartis Pharmaceuticals Corporation; 2005.
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- 15Coadministration of the HCV protease inhibitor boceprevir has no clinically meaningful effect on the pharmacokinetics of the selective serotonin reuptake inhibitor escitalopram in healthy volunteers. Presented at: 16th Annual Meeting of HEP DART; December 4-8, 2011; Koloa, Hawaii., , , , , , et al.
- 16Victrelis (boceprevir) capsules [prescribing information]. Whitehouse Station, NJ: Merck & Co., Inc; 2011.
- 23Triple therapy using telaprevir in the treatment of hepatitis C recurrence after liver transplantation: an early single center experience. Presented at: 16th Annual Meeting of HEP DART; December 4-8, 2011; Koloa, Hawaii., , , , , , et al.
- 24Rebetol (ribavirin UPS) capsules, oral solution [prescribing information]. Kenilworth, NJ: Schering Plough; 2009.
- 25PegIntron (peginterferon alfa-2b) injection [prescribing information]. Kenilworth, NJ: Schering Plough; 2009.