Potential conflict of interest: Nothing to report.
Article first published online: 4 DEC 2012
Copyright © 2012 American Association for the Study of Liver Diseases
Volume 56, Issue 6, pages 2336–2343, December 2012
How to Cite
Zhang, L., Wang, Y.-D., Chen, W.-D., Wang, X., Lou, G., Liu, N., Lin, M., Forman, B. M. and Huang, W. (2012), Promotion of liver regeneration/repair by farnesoid X receptor in both liver and intestine in mice. Hepatology, 56: 2336–2343. doi: 10.1002/hep.25905
L.Z. and W.H. supported by Ibrahim training grant and NCI R01-139158.
- Issue published online: 4 DEC 2012
- Article first published online: 4 DEC 2012
- Accepted manuscript online: 18 JUN 2012 11:57AM EST
- Manuscript Accepted: 3 JUN 2012
- Manuscript Received: 29 JAN 2012
Additional Supporting Information may be found in the online version of this article.
|HEP_25905_sm_SuppFig1.tif||3594K||Supporting Information Figure 1. Impaired liver regeneration of ?L-FXR mice and FXR KO mice after CCl4-induced liver injury. (A) BrdU staining of liver sections from FXR Fl/Fl, ΔL-FXR and FXR KO mice at 24h, 40h, 48h and 72h after CCl4 injection. (B): H&E staining showing liver necrosis in FXR Fl/Fl, ΔL-FXR and FXR KO mice at 24h, 40h, 48h and 72h after CCl4 injection.|
|HEP_25905_sm_SuppFig2.tif||2424K||Supporting Information Figure 2. Impaired liver regeneration in ΔIN-FXR mice after CCl4-induced liver injury. H & E staining of liver sections from FXR Fl/Fl and ΔIN-FXR mice was performed at indicated time points after CCl4 treatment.|
|HEP_25905_sm_SuppFig3.tif||1481K||Supporting Information Figure 3. Ectopic expression of FGF15 rescued defective liver repair in ΔIN-FXR and FXR KO mice BrdU staining of liver sections of the BrdU positive hepatocytes at 0h and 40h after CCl4 injection in ?IN-FXR and FXR KO mice infected with control and FGF15 adenovirus.|
|HEP_25905_sm_SuppTab1.tif||138K||Supporting Information Table 1.|
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