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Additional Supporting Information may be found in the online version of this article.

FilenameFormatSizeDescription
HEP_25905_sm_SuppFig1.tif3594KSupporting Information Figure 1. Impaired liver regeneration of ?L-FXR mice and FXR KO mice after CCl4-induced liver injury. (A) BrdU staining of liver sections from FXR Fl/Fl, ΔL-FXR and FXR KO mice at 24h, 40h, 48h and 72h after CCl4 injection. (B): H&E staining showing liver necrosis in FXR Fl/Fl, ΔL-FXR and FXR KO mice at 24h, 40h, 48h and 72h after CCl4 injection.
HEP_25905_sm_SuppFig2.tif2424KSupporting Information Figure 2. Impaired liver regeneration in ΔIN-FXR mice after CCl4-induced liver injury. H & E staining of liver sections from FXR Fl/Fl and ΔIN-FXR mice was performed at indicated time points after CCl4 treatment.
HEP_25905_sm_SuppFig3.tif1481KSupporting Information Figure 3. Ectopic expression of FGF15 rescued defective liver repair in ΔIN-FXR and FXR KO mice BrdU staining of liver sections of the BrdU positive hepatocytes at 0h and 40h after CCl4 injection in ?IN-FXR and FXR KO mice infected with control and FGF15 adenovirus.
HEP_25905_sm_SuppTab1.tif138KSupporting Information Table 1.

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