Steatohepatitis/Metabolic Liver Disease

In Vivo hyperpolarized carbon-13 magnetic resonance spectroscopy reveals increased pyruvate carboxylase flux in an insulin-resistant mouse model†‡

  1. Philip Lee1,2,§,*,
  2. Waifook Leong1,3,
  3. Trish Tan1,3,
  4. Miangkee Lim1,
  5. Weiping Han1,3,4,
  6. George K. Radda1

Article first published online: 10 JAN 2013

DOI: 10.1002/hep.26028

Issue

Hepatology

Hepatology

Volume 57, Issue 2, pages 515–524, February 2013

Additional Information

How to Cite

Lee, P., Leong, W., Tan, T., Lim, M., Han, W. and Radda, G. K. (2013), In Vivo hyperpolarized carbon-13 magnetic resonance spectroscopy reveals increased pyruvate carboxylase flux in an insulin-resistant mouse model. Hepatology, 57: 515–524. doi: 10.1002/hep.26028

Author Information

  1. 1

    Singapore Bioimaging Consortium, Singapore

  2. 2

    Clinical Imaging Research Centre, National University of Singapore, Center for Translation Medicine, Singapore

  3. 3

    Metabolism in Human Diseases, Institute of Molecular and Cell Biology, Singapore

  4. 4

    Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore

  1. §

    fax: +65 64789957

*Singapore Bioimaging Consortium, 11 Biopolis Way, #02-01 Helios, 138667 Singapore

  1. †

    Potential conflict of interest: Nothing to report.

  2. ‡

    This study was supported by an intramural funding from the A*STAR Biomedical Research Council.

  3. §

    fax: +65 64789957

Publication History

  1. Issue published online: 5 FEB 2013
  2. Article first published online: 10 JAN 2013
  3. Accepted manuscript online: 22 AUG 2012 03:23AM EST
  4. Manuscript Accepted: 8 AUG 2012
  5. Manuscript Received: 16 APR 2012

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