Article first published online: 10 JAN 2013
Copyright © 2012 American Association for the Study of Liver Diseases
Volume 57, Issue 2, pages 775–784, February 2013
How to Cite
Turner, R. A., Wauthier, E., Lozoya, O., McClelland, R., Bowsher, J. E., Barbier, C., Prestwich, G., Hsu, E., Gerber, D. A. and Reid, L. M. (2013), Successful transplantation of human hepatic stem cells with restricted localization to liver using hyaluronan grafts. Hepatology, 57: 775–784. doi: 10.1002/hep.26065
Potential conflict of interest: A patent on the grafting strategies has been filed, is owned by the University of North Carolina, and has been licensed to Vesta Therapeutics for eventual use in clinical programs. None of the authors have equity or a position in Vesta, and none are paid consulting fees by the company. Dr. Reid owns stock in, is a co-founder of, and holds intellectual property rights with Phoenix Sonap Biologicals. Dr. Prestwich is consultant for, received grants from, and holds intellectual property rights with Echelon Biosciences. He owns stock in, consults for, and holds intellectual property rights with BioTime. He owns stock in and holds intellectual property rights with Carbylan and SentrX Animal Care. He owns stock in, is an employee of, received grants from, and holds intellectual property rights with Glycominds.
This work was supported by grants from Vesta Therapeutics, the North Carolina Translational and Clinical Sciences Institute (Grant 2KR50905), the North Carolina Biotechnology Center, the National Institutes of Health (Grant CA016086), and the Department of Energy (Grant 03-SC-DOE-1017). Positron emission tomography studies were performed at the Duke Center for In Vivo Microscopy, a National Center for Research Resources Biomedical Technology Resource Center (P41 RR005959) and Small Animal Imaging Resource Program (U24 CA092656).
Randall McClelland is currently affiliated with SciKon Innovation, Inc., Research Triangle Park, NC.
Edward Hsu is currently affiliated with the Department of Bioengineering, University of Utah, Salt Lake City, UT.
- Issue published online: 5 FEB 2013
- Article first published online: 10 JAN 2013
- Accepted manuscript online: 19 SEP 2012 11:32AM EST
- Manuscript Accepted: 14 AUG 2012
- Manuscript Received: 28 MAR 2012
This article has been cited by:
- 1Cell therapy for liver diseases: current medicine and future promises, Expert Review of Gastroenterology & Hepatology, 2015, 1, , ,
- 3Exploiting the unique regenerative capacity of the liver to underpin cell and gene therapy strategies for genetic and acquired liver disease, The International Journal of Biochemistry & Cell Biology, 2014, 56, 141, , , ,
- 4Thiolated hyaluronan-based hydrogels crosslinked using oxidized glutathione: An injectable matrix designed for ophthalmic applications, Acta Biomaterialia, 2014, 10, 1, 94, , , , , ,
- 5Stem Cells in Development and Disease, 2014,, ,
- 7Percutaneous Intraportal Application of Adipose Tissue–derived Mesenchymal Stem Cells Using a Balloon Occlusion Catheter in a Porcine Model of Liver Fibrosis, Journal of Vascular and Interventional Radiology, 2013, 24, 12, 1871, , , , , , , ,