Joint senior authors
Liver Failure/Cirrhosis/Portal Hypertension
Version of Record online: 12 DEC 2012
Copyright © 2012 American Association for the Study of Liver Diseases
Volume 57, Issue 3, pages 1142–1152, March 2013
How to Cite
Taylor, N. J., Nishtala, A., Manakkat Vijay, G. K., Abeles, R. D., Auzinger, G., Bernal, W., Ma, Y., Wendon, J. A. and Shawcross, D. L. (2013), Circulating neutrophil dysfunction in acute liver failure. Hepatology, 57: 1142–1152. doi: 10.1002/hep.26102
Potential conflict of interest: Nothing to report.
Supported by a Young Investigator Grant awarded to Dr. D.L Shawcross and Professor J.A Wendon from the Intensive Care Society in 2008. Additional laboratory consumables were also funded from the Institute of Liver Studies Liver Intensive Care Charitable Fund. Dr. D.L. Shawcross is funded by a 5-year Department of Health HEFCE Clinical Senior Lectureship and Dr. R.D. Abeles holds a Department of Health NIHR Clinical Research PhD Fellowship.
- Issue online: 28 FEB 2013
- Version of Record online: 12 DEC 2012
- Accepted manuscript online: 18 OCT 2012 12:00AM EST
- Manuscript Accepted: 3 OCT 2012
- Manuscript Received: 22 MAY 2012
Additional Supporting Information may be found in the online version of this article.
|HEP_26102_sm_SuppFig6.tif||8507K||Supporting Information Figure 6a demonstrates the correlation between impaired neutrophil phagocytic activity (%) and elevated arterial ammonia (μmol/L) in the SALF cohort (r2=0.677; p=0.001). Figure 6b demonstrates the correlation between impaired neutrophil phagocytic activity (%) and plasma IL-10 (pg/ml) in the SALF cohort (r2=0.407; p=0.019). Figure 6c demonstrates the correlation between impaired neutrophil phagocytic activity (%) and plasma IL-17 (pg/ml) in the SALF cohort (r2=0.403; p=0.02).|
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