Autoimmune, Cholestatic and Biliary Disease

Oxidative stress plays a major role in chlorpromazine-induced cholestasis in human HepaRG cells†

  1. Sébastien Anthérieu1,2,§,
  2. Pamela Bachour-El Azzi1,2,3,§,
  3. Julie Dumont1,2,‡,
  4. Ziad Abdel-Razzak3,
  5. Christiane Guguen-Guillouzo1,2,4,
  6. Bernard Fromenty1,2,
  7. Marie-Anne Robin1,2,
  8. André Guillouzo1,2,¶,*

Article first published online: 4 MAR 2013

DOI: 10.1002/hep.26160

Issue

Hepatology

Hepatology

Volume 57, Issue 4, pages 1518–1529, April 2013

Additional Information

How to Cite

Anthérieu, S., Azzi, P. B.-E., Dumont, J., Abdel-Razzak, Z., Guguen-Guillouzo, C., Fromenty, B., Robin, M.-A. and Guillouzo, A. (2013), Oxidative stress plays a major role in chlorpromazine-induced cholestasis in human HepaRG cells. Hepatology, 57: 1518–1529. doi: 10.1002/hep.26160

Author Information

  1. 1

    Inserm UMR991, Liver Metabolisms and Cancer, Rennes, France

  2. 2

    Université de Rennes 1, Rennes, France

  3. 3

    Université Libanaise, EDST-PRASE and EDST-AZM-center-LBA3B, Lebanon

  4. 4

    Biopredic International, St Grégoire, France

  1. ‡

    Inserm UMR 744, Université Lille Nord de France, Institut Pasteur, Lille, France

  1. §

    These authors contributed equally to this work.

  2. fax: +33 223235385

*Inserm UMR 991, Faculté des Sciences Pharmaceutiques et Biologiques, 35043 Rennes Cedex, France

  1. †

    Potential conflict of interest: Nothing to report.

  2. §

    These authors contributed equally to this work.

  3. fax: +33 223235385

Publication History

  1. Issue published online: 8 APR 2013
  2. Article first published online: 4 MAR 2013
  3. Accepted manuscript online: 23 NOV 2012 04:11AM EST
  4. Manuscript Accepted: 24 OCT 2012
  5. Manuscript Received: 24 JAN 2012

Funded by

  • European Community Contracts. Grant Numbers: LIINTOP-STREP-037499, Predict-IV-202222
  • Pamela Bachour-El Azzi was provided by Lebanese University, Lebanese CNRS, Philippe Jabre association and the Ecole Doctorale VAS Rennes

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